Engineered in vitro disease models KH Benam, S Dauth, B Hassell, A Herland, A Jain, KJ Jang, K Karalis, ... Annual Review of Pathology: Mechanisms of Disease 10 (1), 195-262, 2015 | 617 | 2015 |
Autocrine or paracrine inflammatory actions of corticotropin-releasing hormone in vivo K Karalis, H Sano, J Redwine, S Listwak, RL Wilder, GP Chrousos Science 254 (5030), 421-423, 1991 | 573 | 1991 |
Cardiovascular disease, chronic kidney disease, and diabetes mortality burden of cardiometabolic risk factors from 1980 to 2010: a comparative risk assessment G Danaei, Y Lu, GM Singh, E Carnahan, GA Stevens, MJ Cowan, ... Lancet Diabetes & Endocrinology, 2014 | 476 | 2014 |
TNF-α and obesity T Tzanavari, P Giannogonas, KP Karalis TNF Pathophysiology 11, 145-156, 2010 | 464 | 2010 |
Reproducing human and cross-species drug toxicities using a Liver-Chip KJ Jang, MA Otieno, J Ronxhi, HK Lim, L Ewart, KR Kodella, ... Science translational medicine 11 (517), eaax5516, 2019 | 371 | 2019 |
Deciphering osteoarthritis genetics across 826,690 individuals from 9 populations CG Boer, K Hatzikotoulas, L Southam, L Stefánsdóttir, Y Zhang, ... Cell 184 (18), 4784-4818. e17, 2021 | 340 | 2021 |
Cortisol blockade of progesterone: a possible molecular mechanism involved in the initiation of human labor K Karalis, G Goodwin, JA Majzoub Nature medicine 2 (5), 556-560, 1996 | 324 | 1996 |
Corticotropin-releasing hormone in synovial fluids and tissues of patients with rheumatoid arthritis and osteoarthritis. LJ Crofford, H Sano, K Karalis, TC Friedman, HR Epps, EF Remmers, ... Journal of immunology (Baltimore, Md.: 1950) 151 (3), 1587-1596, 1993 | 259 | 1993 |
CRH and the immune system K Karalis, LJ Muglia, D Bae, H Hilderbrand, JA Majzoub Journal of neuroimmunology 72 (2), 131-136, 1997 | 250 | 1997 |
Local secretion of corticotropin-releasing hormone in the joints of Lewis rats with inflammatory arthritis. LJ Crofford, H Sano, K Karalis, EL Webster, EA Goldmuntz, GP Chrousos, ... The Journal of clinical investigation 90 (6), 2555-2564, 1992 | 243 | 1992 |
Somatostatin analogues suppress the inflammatory reaction in vivo. K Karalis, G Mastorakos, GP Chrousos, G Tolis The Journal of clinical investigation 93 (5), 2000-2006, 1994 | 224 | 1994 |
Mechanisms of obesity and related pathology: linking immune responses to metabolic stress KP Karalis, P Giannogonas, E Kodela, Y Koutmani, M Zoumakis, T Teli The FEBS journal 276 (20), 5747-5754, 2009 | 211 | 2009 |
Placental corticotropin-releasing hormone: function and regulation JA Majzoub, KP Karalis American journal of obstetrics and gynecology 180 (1), S242-S246, 1999 | 201 | 1999 |
Sequencing of 640,000 exomes identifies GPR75 variants associated with protection from obesity P Akbari, A Gilani, O Sosina, JA Kosmicki, L Khrimian, YY Fang, ... Science 373 (6550), eabf8683, 2021 | 199 | 2021 |
Lymphocytes in obesity-related adipose tissue inflammation A Chatzigeorgiou, KP Karalis, SR Bornstein, T Chavakis Diabetologia 55 (10), 2583-2592, 2012 | 181 | 2012 |
Duodenum Intestine-Chip for preclinical drug assessment in a human relevant model M Kasendra, R Luc, J Yin, DV Manatakis, G Kulkarni, C Lucchesi, J Sliz, ... Elife 9, e50135, 2020 | 178 | 2020 |
Corticotropin-releasing hormone regulates IL-6 expression during inflammation M Venihaki, P Dikkes, A Carrigan, KP Karalis The Journal of Clinical Investigation 108 (8), 1159-1166, 2001 | 172 | 2001 |
Mapping metabolic changes by noninvasive, multiparametric, high-resolution imaging using endogenous contrast Z Liu, D Pouli, CA Alonzo, A Varone, S Karaliota, KP Quinn, K Münger, ... Science advances 4 (3), eaap9302, 2018 | 169 | 2018 |
A self-sustained loop of inflammation-driven inhibition of beige adipogenesis in obesity KJ Chung, A Chatzigeorgiou, M Economopoulou, R Garcia-Martin, ... Nature immunology 18 (6), 654-664, 2017 | 162 | 2017 |
Bioengineered human organ-on-chip reveals intestinal microenvironment and mechanical forces impacting Shigella infection A Grassart, V Malardé, S Gobaa, A Sartori-Rupp, J Kerns, K Karalis, ... Cell host & microbe 26 (3), 435-444. e4, 2019 | 158 | 2019 |