Structural and mechanistic insights into bisphenols action provide guidelines for risk assessment and discovery of bisphenol A substitutes V Delfosse, M Grimaldi, JL Pons, A Boulahtouf, A Le Maire, V Cavailles, ... Proceedings of the National Academy of Sciences 109 (37), 14930-14935, 2012 | 388 | 2012 |
Peroxisome proliferator-activated receptor γ is a target for halogenated analogs of bisphenol A A Riu, M Grimaldi, A Le Maire, G Bey, K Phillips, A Boulahtouf, E Perdu, ... Environmental health perspectives 119 (9), 1227-1232, 2011 | 319 | 2011 |
Activation of RXR–PPAR heterodimers by organotin environmental endocrine disruptors A Le Maire, M Grimaldi, D Roecklin, S Dagnino, V Vivat‐Hannah, ... EMBO reports 10 (4), 367-373, 2009 | 288 | 2009 |
A unique secondary-structure switch controls constitutive gene repression by retinoic acid receptor A Le Maire, C Teyssier, C Erb, M Grimaldi, S Alvarez, AR De Lera, ... Nature structural & molecular biology 17 (7), 801-807, 2010 | 168 | 2010 |
Characterization of novel ligands of ERα, Erβ, and PPARγ: the case of halogenated bisphenol A and their conjugated metabolites A Riu, A Le Maire, M Grimaldi, M Audebert, A Hillenweck, W Bourguet, ... Toxicological Sciences 122 (2), 372-382, 2011 | 156 | 2011 |
A structural view of nuclear hormone receptor: endocrine disruptor interactions A Le Maire, W Bourguet, P Balaguer Cellular and molecular life sciences 67, 1219-1237, 2010 | 138 | 2010 |
A structural perspective on nuclear receptors as targets of environmental compounds V Delfosse, A Maire, P Balaguer, W Bourguet Acta Pharmacologica Sinica 36 (1), 88-101, 2015 | 126 | 2015 |
Retinoid receptors and therapeutic applications of RAR/RXR modulators A le Maire, S Alvarez, P Shankaranarayanan, A R de Lera, W Bourguet, ... Current topics in medicinal chemistry 12 (6), 505-527, 2012 | 111 | 2012 |
Nuclear receptor profiling of bisphenol-A and its halogenated analogues V Delfosse, M Grimaldi, A Le Maire, W Bourguet, P Balaguer Vitamins & Hormones 94, 229-251, 2014 | 104 | 2014 |
In-plate protein crystallization, in situ ligand soaking and X-ray diffraction A Le Maire, M Gelin, S Pochet, F Hoh, M Pirocchi, JF Guichou, JL Ferrer, ... Acta Crystallographica Section D: Biological Crystallography 67 (9), 747-755, 2011 | 93 | 2011 |
Regulation of RXR-RAR heterodimers by RXR-and RAR-specific ligands and their combinations A Le Maire, C Teyssier, P Balaguer, W Bourguet, P Germain Cells 8 (11), 1392, 2019 | 81 | 2019 |
Interplay of protein disorder in retinoic acid receptor heterodimer and its corepressor regulates gene expression TN Cordeiro, N Sibille, P Germain, P Barthe, A Boulahtouf, F Allemand, ... Structure 27 (8), 1270-1285. e6, 2019 | 52 | 2019 |
The human mixed lineage leukemia 5 (MLL5), a sequentially and structurally divergent SET domain-containing protein with no intrinsic catalytic activity S Mas-y-Mas, M Barbon, C Teyssier, H Déméné, JE Carvalho, LE Bird, ... PloS one 11 (11), e0165139, 2016 | 50 | 2016 |
Retinoic acid receptors: structural basis for coregulator interaction and exchange A le Maire, W Bourguet The Biochemistry of Retinoic Acid Receptors I: Structure, Activation, and …, 2014 | 39 | 2014 |
Screening for PPAR non-agonist ligands followed by characterization of a hit, AM-879, with additional no-adipogenic and cdk5-mediated phosphorylation inhibition properties HV Ribeiro Filho, N Bernardi Videira, AV Bridi, TH Tittanegro, ... Frontiers in endocrinology 9, 11, 2018 | 31 | 2018 |
A tandem of SH3-like domains participates in RNA binding in KIN17, a human protein activated in response to genotoxics A Le Maire, M Schiltz, EA Stura, G Pinon-Lataillade, J Couprie, M Moutiez, ... Journal of molecular biology 364 (4), 764-776, 2006 | 27 | 2006 |
Solution structure of the region 51–160 of human KIN17 reveals an atypical winged helix domain L Carlier, J Couprie, A Le Maire, L Guilhaudis, I Milazzo‐Segalas, ... Protein Science 16 (12), 2750-2755, 2007 | 26 | 2007 |
Two Novel Cases of Resistance to Thyroid Hormone Due to THRA Mutation A Le Maire, N Bouhours-Nouet, J Soamalala, D Mirebeau-Prunier, ... Thyroid 30 (8), 1217-1221, 2020 | 24 | 2020 |
Exploring the mechanism of PPARγ phosphorylation mediated by CDK5 HV Ribeiro Filho, JV Guerra, R Cagliari, FAH Batista, A Le Maire, ... Journal of Structural Biology 207 (3), 317-326, 2019 | 16 | 2019 |
Structural insights into the interaction of the intrinsically disordered co-activator TIF2 with retinoic acid receptor heterodimer (RXR/RAR) L Senicourt, A Le Maire, F Allemand, JÃE Carvalho, L Guee, P Germain, ... Journal of molecular biology 433 (9), 166899, 2021 | 15 | 2021 |