| Enantioselective dichlorination of allylic alcohols KC Nicolaou, NL Simmons, Y Ying, PM Heretsch, JS Chen Journal of the American Chemical Society 133 (21), 8134-8137, 2011 | 252 | 2011 |
| Carbonylative Cross-Coupling of ortho-Disubstituted Aryl Iodides. Convenient Synthesis of Sterically Hindered Aryl Ketones BM O’Keefe, N Simmons, SF Martin Organic letters 10 (22), 5301-5304, 2008 | 125 | 2008 |
| A Mild, DNA-Compatible Nitro Reduction Using B2(OH)4 HC Du, N Simmons, JC Faver, Z Yu, M Palaniappan, K Riehle, ... Organic Letters 21 (7), 2194-2199, 2019 | 65 | 2019 |
| Quantitative comparison of enrichment from DNA-encoded chemical library selections JC Faver, K Riehle, DR Lancia Jr, JBJ Milbank, CS Kollmann, N Simmons, ... ACS combinatorial science 21 (2), 75-82, 2019 | 61 | 2019 |
| Total synthesis and biological evaluation of marinopyrrole A and analogs KC Nicolaou, NL Simmons, JS Chen, NM Haste, V Nizet Tetrahedron letters 52 (17), 2041-2043, 2011 | 51 | 2011 |
| Discovery of potent thrombin inhibitors from a protease-focused DNA-encoded chemical library S Dawadi, N Simmons, G Miklossy, KM Bohren, JC Faver, MN Ucisik, ... Proceedings of the National Academy of Sciences 117 (29), 16782-16789, 2020 | 50 | 2020 |
| Discovery and characterization of bromodomain 2–specific inhibitors of BRDT Z Yu, AF Ku, JL Anglin, R Sharma, MN Ucisik, JC Faver, F Li, ... Proceedings of the National Academy of Sciences 118 (9), e2021102118, 2021 | 49 | 2021 |
| Facile access to sterically hindered aryl ketones via carbonylative cross-coupling: application to the total synthesis of luteolin BM O’Keefe, N Simmons, SF Martin Tetrahedron 67 (24), 4344-4351, 2011 | 47 | 2011 |
| C–N coupling of DNA-conjugated (hetero) aryl bromides and chlorides for DNA-encoded chemical library synthesis YC Chen, JC Faver, AF Ku, G Miklossy, K Riehle, KM Bohren, MN Ucisik, ... Bioconjugate Chemistry 31 (3), 770-780, 2020 | 46 | 2020 |
| Identifying oxacillinase-48 carbapenemase inhibitors using DNA-encoded chemical libraries DM Taylor, J Anglin, S Park, MN Ucisik, JC Faver, N Simmons, Z Jin, ... ACS infectious diseases 6 (5), 1214-1227, 2020 | 37 | 2020 |
| Homogeneous and functional group tolerant ring-closing metathesis for DNA-encoded chemical libraries OBC Monty, P Nyshadham, KM Bohren, M Palaniappan, MM Matzuk, ... ACS combinatorial science 22 (2), 80-88, 2020 | 35 | 2020 |
| Synthesis and antioxidant evaluation of (S, S)-and (R, R)-secoisolariciresinol diglucosides (SDGs) OP Mishra, N Simmons, S Tyagi, R Pietrofesa, VV Shuvaev, RA Valiulin, ... Bioorganic & medicinal chemistry letters 23 (19), 5325-5328, 2013 | 35 | 2013 |
| Trends in hit-to-lead optimization following DNA-encoded library screens CA Reiher, DP Schuman, N Simmons, SE Wolkenberg ACS Medicinal Chemistry Letters 12 (3), 343-350, 2021 | 31 | 2021 |
| Palladium-catalyzed hydroxycarbonylation of (hetero) aryl halides for DNA-encoded chemical library synthesis JY Li, G Miklossy, RK Modukuri, KM Bohren, Z Yu, M Palaniappan, ... Bioconjugate chemistry 30 (8), 2209-2215, 2019 | 28 | 2019 |
| Multistep synthesis of 1, 2, 4-oxadiazoles via DNA-conjugated aryl nitrile substrates HC Du, MC Bangs, N Simmons, MM Matzuk Bioconjugate chemistry 30 (5), 1304-1308, 2019 | 27 | 2019 |
| Discovery of potent BET bromodomain 1 stereoselective inhibitors using DNA-encoded chemical library selections RK Modukuri, Z Yu, Z Tan, HM Ta, MN Ucisik, Z Jin, JL Anglin, KL Sharma, ... Proceedings of the National Academy of Sciences 119 (22), e2122506119, 2022 | 22 | 2022 |
| Solution-phase Fmoc-based peptide synthesis for DNA-encoded chemical libraries: reaction conditions, protecting group strategies, and pitfalls OBC Monty, N Simmons, S Chamakuri, MM Matzuk, DW Young ACS Combinatorial Science 22 (12), 833-843, 2020 | 20 | 2020 |
| Cyclic Marinopyrrole Derivatives as Disruptors of Mcl-1 and Bcl-xL Binding to Bim C Cheng, Y Liu, ME Balasis, NL Simmons, J Li, H Song, L Pan, Y Qin, ... Marine drugs 12 (3), 1335-1348, 2014 | 20 | 2014 |
| Palladium-Mediated C–N Coupling of DNA-Conjugated (Hetero) aryl Halides with Aliphatic and (Hetero) aromatic Amines PR Chheda, N Simmons, DP Schuman, Z Shi Organic Letters 24 (18), 3401-3406, 2022 | 16 | 2022 |
| Marinopyrrole derivatives with sulfide spacers as selective disruptors of Mcl-1 binding to pro-apoptotic protein Bim C Cheng, Y Liu, ME Balasis, TP Garner, J Li, NL Simmons, N Berndt, ... Marine Drugs 12 (8), 4311-4325, 2014 | 14 | 2014 |
