Structure-based discovery of fiber-binding compounds that reduce the cytotoxicity of amyloid beta L Jiang, C Liu, D Leibly, M Landau, M Zhao, MP Hughes, DS Eisenberg Elife 2, e00857, 2013 | 155 | 2013 |
Stabilizing additives added during cell lysis aid in the solubilization of recombinant proteins DJ Leibly, TN Nguyen, LT Kao, SN Hewitt, LK Barrett, WC Van Voorhis PloS one 7 (12), e52482, 2012 | 145 | 2012 |
Transmission of malaria to mosquitoes blocked by bumped kinase inhibitors KK Ojo, C Pfander, NR Mueller, C Burstroem, ET Larson, CM Bryan, ... The Journal of clinical investigation 122 (6), 2301-2305, 2012 | 115 | 2012 |
Immobilized metal-affinity chromatography protein-recovery screening is predictive of crystallographic structure success R Choi, A Kelley, D Leibly, S Nakazawa Hewitt, A Napuli, W Van Voorhis Acta Crystallographica Section F: Structural Biology and Crystallization …, 2011 | 96 | 2011 |
Identification of inhibitors for putative malaria drug targets among novel antimalarial compounds GJ Crowther, AJ Napuli, JH Gilligan, K Gagaring, R Borboa, C Francek, ... Molecular and biochemical parasitology 175 (1), 21-29, 2011 | 96 | 2011 |
High-throughput protein production and purification at the Seattle Structural Genomics Center for Infectious Disease CM Bryan, J Bhandari, AJ Napuli, DJ Leibly, R Choi, A Kelley, ... Acta Crystallographica Section F: Structural Biology and Crystallization …, 2011 | 94 | 2011 |
Multiple determinants for selective inhibition of apicomplexan calcium-dependent protein kinase CDPK1 ET Larson, KK Ojo, RC Murphy, SM Johnson, Z Zhang, JE Kim, DJ Leibly, ... Journal of Medicinal Chemistry 55 (6), 2803-2810, 2012 | 75 | 2012 |
Buffer Optimization of Thermal Melt Assays of Plasmodium Proteins for Detection of Small-Molecule Ligands GJ Crowther, AJ Napuli, AP Thomas, DJ Chung, KV Kovzun, DJ Leibly, ... Journal of biomolecular screening 14 (6), 700-707, 2009 | 55 | 2009 |
A suite of engineered GFP molecules for oligomeric scaffolding DJ Leibly, MA Arbing, I Pashkov, N DeVore, GS Waldo, TC Terwilliger, ... Structure 23 (9), 1754-1768, 2015 | 43 | 2015 |
Structure of a Burkholderia pseudomallei trimeric autotransporter adhesin head TE Edwards, I Phan, J Abendroth, SH Dieterich, A Masoudi, W Guo, ... PLoS One 5 (9), e12803, 2010 | 39 | 2010 |
An allosteric model for control of pore opening by substrate binding in the E ut L microcompartment shell protein MC Thompson, D Cascio, DJ Leibly, TO Yeates Protein Science 24 (6), 956-975, 2015 | 38 | 2015 |
Use of thermal melt curves to assess the quality of enzyme preparations GJ Crowther, P He, PP Rodenbough, AP Thomas, KV Kovzun, DJ Leibly, ... Analytical biochemistry 399 (2), 268-275, 2010 | 37 | 2010 |
Structure of a novel 13 nm dodecahedral nanocage assembled from a redesigned bacterial microcompartment shell protein J Jorda, DJ Leibly, MC Thompson, TO Yeates Chemical Communications 52 (28), 5041-5044, 2016 | 35 | 2016 |
Biocatalytic synthesis of α-amino ketones SW Chun, ARH Narayan Synlett 30 (11), 1269-1274, 2019 | 22 | 2019 |
Structures of phosphopantetheine adenylyltransferase from Burkholderia pseudomallei TE Edwards, DJ Leibly, J Bhandari, JB Statnekov, I Phan, SH Dieterich, ... Acta Crystallographica Section F: Structural Biology and Crystallization …, 2011 | 16 | 2011 |
Structure of the cystathionine γ-synthase MetB from Mycobacterium ulcerans MC Clifton, J Abendroth, TE Edwards, DJ Leibly, AK Gillespie, M Ferrell, ... Acta Crystallographica Section F: Structural Biology and Crystallization …, 2011 | 14 | 2011 |
Structural characterization of a ribose-5-phosphate isomerase B from the pathogenic fungus Coccidioides immitis TE Edwards, AB Abramov, ER Smith, RO Baydo, JT Leonard, DJ Leibly, ... BMC Structural Biology 11, 1-9, 2011 | 8 | 2011 |
Structure of triosephosphate isomerase from Cryptosporidium parvum TN Nguyen, J Abendroth, DJ Leibly, KP Le, W Guo, A Kelley, L Stewart, ... Acta Crystallographica Section F: Structural Biology and Crystallization …, 2011 | 6 | 2011 |
Structures of a putative ζ-class glutathione S-transferase from the pathogenic fungus Coccidioides immitis TE Edwards, CM Bryan, DJ Leibly, SH Dieterich, J Abendroth, B Sankaran, ... Acta Crystallographica Section F: Structural Biology and Crystallization …, 2011 | 5 | 2011 |
Structure of thymidylate kinase from Ehrlichia chaffeensis DJ Leibly, J Abendroth, CM Bryan, B Sankaran, A Kelley, LK Barrett, ... Acta Crystallographica Section F: Structural Biology and Crystallization …, 2011 | 2 | 2011 |