Genetic interactions contribute less than additive effects to quantitative trait variation in yeast JS Bloom, I Kotenko, MJ Sadhu, S Treusch, FW Albert, L Kruglyak Nature communications 6 (1), 8712, 2015 | 161 | 2015 |
Accounting for genetic interactions improves modeling of individual quantitative trait phenotypes in yeast SKG Forsberg, JS Bloom, MJ Sadhu, L Kruglyak, Ö Carlborg Nature genetics 49 (4), 497-503, 2017 | 143 | 2017 |
CRISPR-directed mitotic recombination enables genetic mapping without crosses MJ Sadhu, JS Bloom, L Day, L Kruglyak Science 352 (6289), 1113-1116, 2016 | 120 | 2016 |
Highly parallel genome variant engineering with CRISPR–Cas9 MJ Sadhu, JS Bloom, L Day, JJ Siegel, S Kosuri, L Kruglyak Nature genetics 50 (4), 510-514, 2018 | 87 | 2018 |
Rare variants contribute disproportionately to quantitative trait variation in yeast JS Bloom, J Boocock, S Treusch, MJ Sadhu, L Day, H Oates-Barker, ... Elife 8, e49212, 2019 | 78 | 2019 |
Nutritional control of epigenetic processes in yeast and human cells MJ Sadhu, Q Guan, F Li, J Sales-Lee, AT Iavarone, MC Hammond, ... Genetics 195 (3), 831-844, 2013 | 69 | 2013 |
Multiple inputs control sulfur-containing amino acid synthesis in Saccharomyces cerevisiae MJ Sadhu, JJ Moresco, AD Zimmer, JR Yates III, J Rine Molecular biology of the cell 25 (10), 1653-1665, 2014 | 40 | 2014 |
Ancient balancing selection maintains incompatible versions of the galactose pathway in yeast J Boocock, MJ Sadhu, A Durvasula, JS Bloom, L Kruglyak Science 371 (6527), 415-419, 2021 | 28 | 2021 |
Genome-wide base editor screen identifies regulators of protein abundance in yeast OT Schubert, JS Bloom, MJ Sadhu, L Kruglyak Elife 11, e79525, 2022 | 13 | 2022 |
Identification of genes regulating sensory neuron genesis and differentiation in the avian dorsal root ganglia BR Nelson, M Sadhu, JC Kasemeier, LW Anderson, F Lefcort Developmental Dynamics: An Official Publication of the American Association …, 2004 | 12 | 2004 |
Evolutionary Analysis of Heterochromatin Protein Compatibility by Interspecies Complementation in Saccharomyces OA Zill, DR Scannell, J Kuei, M Sadhu, J Rine Genetics 192 (3), 1001-1014, 2012 | 8 | 2012 |
Highly complete long-read genomes reveal pangenomic variation underlying yeast phenotypic diversity CA Weller, I Andreev, MJ Chambers, M Park, JS Bloom, MJ Sadhu, ... Genome Research 33 (5), 729-740, 2023 | 3* | 2023 |
Discovery of a rapidly evolving yeast defense factor, KTD1, against the secreted killer toxin K28 I Andreev, KME Laidlaw, SM Giovanetti, G Urtecho, D Shriner, JS Bloom, ... Proceedings of the National Academy of Sciences 120 (8), e2217194120, 2023 | 3* | 2023 |
Analysis of the genetic basis of height in large Jewish nuclear families D Zeevi, JS Bloom, MJ Sadhu, A Ben Yehuda, D Zangen, E Levy-Lahad, ... PLoS genetics 15 (7), e1008082, 2019 | 3 | 2019 |
How low can you go? MJ Sadhu, L Kruglyak The CRISPR Journal 1, 312-313, 2018 | 1 | 2018 |
Systematic genetic characterization of the human PKR kinase domain highlights its functional malleability to escape a viral substrate mimic MJ Chambers, SB Scobell, MJ Sadhu bioRxiv, 2024.05. 29.596416, 2024 | | 2024 |
Improved vectors for retron-mediated CRISPR-Cas9 genome editing in Saccharomyces cerevisiae TN Stuecker, SE Hood, J Molina Pineda, S Lenaduwe, J Winter, ... bioRxiv, 2024.08. 06.606807, 2024 | | 2024 |
Comprehensive deletion scan of anti-CRISPR AcrIIA4 reveals essential and dispensable domains for Cas9 inhibition AB Iturralde, CA Weller, MJ Sadhu bioRxiv, 2024.07. 09.602757, 2024 | | 2024 |
Genetics without crosses: Quantitative trait mapping with CRISPR M Sadhu, J Bloom, L Kruglyak YEAST 32, S269-S269, 2015 | | 2015 |
Interactions between Nutrition, Chromatin, and Gene Regulation in Yeasts MJ Sadhu UC Berkeley, 2012 | | 2012 |