Blood phosphorylated tau 181 as a biomarker for Alzheimer's disease: a diagnostic performance and prediction modelling study using data from four prospective cohorts TK Karikari, TA Pascoal, NJ Ashton, S Janelidze, AL Benedet, ... The Lancet Neurology 19 (5), 422-433, 2020 | 927 | 2020 |
Plasma p-tau231: a new biomarker for incipient Alzheimer’s disease pathology NJ Ashton, TA Pascoal, TK Karikari, AL Benedet, J Lantero-Rodriguez, ... Acta neuropathologica 141, 709-724, 2021 | 419 | 2021 |
Microglial activation and tau propagate jointly across Braak stages TA Pascoal, AL Benedet, NJ Ashton, MS Kang, J Therriault, M Chamoun, ... Nature medicine 27 (9), 1592-1599, 2021 | 338 | 2021 |
A multicentre validation study of the diagnostic value of plasma neurofilament light NJ Ashton, S Janelidze, A Al Khleifat, A Leuzy, EL van der Ende, ... Nature communications 12 (1), 3400, 2021 | 314 | 2021 |
Differences between plasma and cerebrospinal fluid glial fibrillary acidic protein levels across the Alzheimer disease continuum AL Benedet, M Milà-Alomà, A Vrillon, NJ Ashton, TA Pascoal, F Lussier, ... JAMA neurology 78 (12), 1471-1483, 2021 | 279 | 2021 |
Diagnostic performance and prediction of clinical progression of plasma phospho-tau181 in the Alzheimer’s Disease Neuroimaging Initiative TK Karikari, AL Benedet, NJ Ashton, J Lantero Rodriguez, A Snellman, ... Molecular psychiatry 26 (2), 429-442, 2021 | 256 | 2021 |
The diagnostic and prognostic capabilities of plasma biomarkers in Alzheimer's disease J Simrén, A Leuzy, TK Karikari, A Hye, AL Benedet, J Lantero‐Rodriguez, ... Alzheimer's & Dementia 17 (7), 1145-1156, 2021 | 231 | 2021 |
Plasma p-tau231 and p-tau217 as state markers of amyloid-β pathology in preclinical Alzheimer’s disease M Milà-Alomà, NJ Ashton, M Shekari, G Salvadó, P Ortiz-Romero, ... Nature Medicine 28 (9), 1797-1801, 2022 | 230 | 2022 |
Association of apolipoprotein E ε4 with medial temporal tau independent of amyloid-β J Therriault, AL Benedet, TA Pascoal, S Mathotaarachchi, M Chamoun, ... JAMA neurology 77 (4), 470-479, 2020 | 198 | 2020 |
18F-MK-6240 PET for early and late detection of neurofibrillary tangles TA Pascoal, J Therriault, AL Benedet, M Savard, FZ Lussier, M Chamoun, ... Brain 143 (9), 2818-2830, 2020 | 181 | 2020 |
Blood phospho-tau in Alzheimer disease: analysis, interpretation, and clinical utility TK Karikari, NJ Ashton, G Brinkmalm, WS Brum, AL Benedet, ... Nature Reviews Neurology 18 (7), 400-418, 2022 | 153 | 2022 |
In vivo quantification of neurofibrillary tangles with [18F]MK-6240 TA Pascoal, M Shin, MS Kang, M Chamoun, D Chartrand, ... Alzheimer's research & therapy 10, 1-14, 2018 | 153 | 2018 |
Amyloid-β and hyperphosphorylated tau synergy drives metabolic decline in preclinical Alzheimer’s disease TA Pascoal, S Mathotaarachchi, S Mohades, AL Benedet, CO Chung, ... Molecular psychiatry 22 (2), 306-311, 2017 | 139 | 2017 |
Mild behavioral impairment is associated with β‐amyloid but not tau or neurodegeneration in cognitively intact elderly individuals FZ Lussier, TA Pascoal, M Chamoun, J Therriault, C Tissot, M Savard, ... Alzheimer's & dementia 16 (1), 192-199, 2020 | 134 | 2020 |
Biomarker modeling of Alzheimer’s disease using PET-based Braak staging J Therriault, TA Pascoal, FZ Lussier, C Tissot, M Chamoun, G Bezgin, ... Nature aging 2 (6), 526-535, 2022 | 133 | 2022 |
Identifying incipient dementia individuals using machine learning and amyloid imaging S Mathotaarachchi, TA Pascoal, M Shin, AL Benedet, MS Kang, ... Neurobiology of aging 59, 80-90, 2017 | 121 | 2017 |
Synergistic interaction between amyloid and tau predicts the progression to dementia TA Pascoal, S Mathotaarachchi, M Shin, AL Benedet, S Mohades, ... Alzheimer's & Dementia 13 (6), 644-653, 2017 | 119 | 2017 |
Tracking neuroinflammation in Alzheimer’s disease: the role of positron emission tomography imaging ER Zimmer, A Leuzy, AL Benedet, J Breitner, S Gauthier, P Rosa-Neto Journal of neuroinflammation 11, 1-12, 2014 | 117 | 2014 |
Astrocyte reactivity influences amyloid-β effects on tau pathology in preclinical Alzheimer’s disease B Bellaver, G Povala, PCL Ferreira, JP Ferrari-Souza, DT Leffa, ... Nature medicine 29 (7), 1775-1781, 2023 | 103 | 2023 |
Cerebrospinal fluid p-tau231 as an early indicator of emerging pathology in Alzheimer's disease NJ Ashton, AL Benedet, TA Pascoal, TK Karikari, J Lantero-Rodriguez, ... EBioMedicine 76, 2022 | 103 | 2022 |