Articles with public access mandates - Arnoud BootLearn more
Available somewhere: 29
Review
The repertoire of mutational signatures in human cancer
LB Alexandrov, J Kim, NJ Haradhvala, MN Huang, AW Tian Ng, Y Wu, ...
Nature 578 (7793), 94-101, 2020
Mandates: US National Institutes of Health, Cancer Research UK, Wellcome Trust …
Review
Pan-cancer analysis of whole genomes
Nature 578 (7793), 82-93, 2020
Mandates: US National Institutes of Health, Cancer Research UK, UK Medical Research …
Review
Whole-genome and epigenomic landscapes of etiologically distinct subtypes of cholangiocarcinoma
A Jusakul, I Cutcutache, CH Yong, JQ Lim, MN Huang, N Padmanabhan, ...
Cancer discovery 7 (10), 1116-1135, 2017
Mandates: US Department of Energy, US National Institutes of Health, National Natural …
Review
Aristolochic acids and their derivatives are widely implicated in liver cancers in Taiwan and throughout Asia
AWT Ng, SL Poon, MN Huang, JQ Lim, A Boot, W Yu, Y Suzuki, ...
Science translational medicine 9 (412), eaan6446, 2017
Mandates: National Medical Research Council, Singapore, Ministry of Health, Singapore
Review
Somatic POLE proofreading domain mutation, immune response, and prognosis in colorectal cancer: a retrospective, pooled biomarker study
E Domingo, L Freeman-Mills, E Rayner, M Glaire, S Briggs, L Vermeulen, ...
The lancet Gastroenterology & hepatology 1 (3), 207-216, 2016
Mandates: Academy of Medical Sciences, UK, Cancer Research UK, National Institute for …
Review
Genomic and transcriptomic profiling of combined hepatocellular and intrahepatic cholangiocarcinoma reveals distinct molecular subtypes
R Xue, LU Chen, C Zhang, M Fujita, R Li, SM Yan, CK Ong, X Liao, Q Gao, ...
Cancer cell 35 (6), 932-947. e8, 2019
Mandates: US National Institutes of Health, National Natural Science Foundation of China
Review
In-depth characterization of the cisplatin mutational signature in human cell lines and in esophageal and liver tumors
A Boot, MN Huang, AWT Ng, SC Ho, JQ Lim, Y Kawakami, K Chayama, ...
Genome research 28 (5), 654-665, 2018
Mandates: National Medical Research Council, Singapore
Review
Genome-scale mutational signatures of aflatoxin in cells, mice, and human tumors
MN Huang, W Yu, WW Teoh, M Ardin, A Jusakul, AWT Ng, A Boot, ...
Genome research 27 (9), 1475-1486, 2017
Mandates: US National Institutes of Health, National Institute of Health and Medical …
Review
Multiomic analysis and immunoprofiling reveal distinct subtypes of human angiosarcoma
JY Chan, JQ Lim, J Yeong, V Ravi, P Guan, A Boot, TKY Tay, ...
The Journal of clinical investigation 130 (11), 5833-5846, 2020
Mandates: National Medical Research Council, Singapore
Review
Characterization of colibactin-associated mutational signature in an Asian oral squamous cell carcinoma and in other mucosal tumor types
A Boot, AWT Ng, FT Chong, SC Ho, W Yu, DSW Tan, NG Iyer, SG Rozen
Genome Research 30 (6), 803-813, 2020
Mandates: National Medical Research Council, Singapore
Review
The mutational landscape of early‐and typical‐onset oral tongue squamous cell carcinoma
BR Campbell, Z Chen, DL Faden, N Agrawal, RJ Li, GJ Hanna, NG Iyer, ...
Cancer 127 (4), 544-553, 2021
Mandates: US National Institutes of Health
Review
A tumor-associated splice-isoform of MAP2K7 drives dedifferentiation in MBNL1-low cancers via JNK activation
D Ray, YC Yun, M Idris, S Cheng, A Boot, TBH Iain, SG Rozen, P Tan, ...
Proceedings of the National Academy of Sciences 117 (28), 16391-16400, 2020
Mandates: National Medical Research Council, Singapore
Review
Recurrent coding sequence variation explains only a small fraction of the genetic architecture of colorectal cancer
MN Timofeeva, B Kinnersley, SM Farrington, N Whiffin, C Palles, V Svinti, ...
Scientific reports 5 (1), 16286, 2015
Mandates: UK Biotechnology and Biological Sciences Research Council, Cancer Research …
Review
Recurrent mutations in topoisomerase IIα cause a previously undescribed mutator phenotype in human cancers
A Boot, M Liu, N Stantial, V Shah, W Yu, KC Nitiss, JL Nitiss, ...
Proceedings of the National Academy of Sciences 119 (4), e2114024119, 2022
Mandates: US National Institutes of Health, National Medical Research Council, Singapore
Review
ROS-induced near-homozygous genomes in thyroid cancer
WE Corver, J Demmers, J Oosting, S Sahraeian, A Boot, D Ruano, ...
Endocrine-related cancer 25 (1), 83-97, 2018
Mandates: Dutch Cancer Society
Review
Monoallelic NTHL1 loss-of-function variants and risk of polyposis and colorectal cancer
FA Elsayed, JE Grolleman, A Ragunathan, A Boot, MS Stojovska, ...
Gastroenterology 159 (6), 2241-2243. e6, 2020
Mandates: US National Institutes of Health, National Health and Medical Research …
Review
Recurrent APC splice variant c. 835-8A> G in patients with unexplained colorectal polyposis fulfilling the colibactin mutational signature
D Terlouw, M Suerink, A Boot, T van Wezel, M Nielsen, H Morreau
Gastroenterology 159 (4), 1612-1614. e5, 2020
Mandates: Dutch Cancer Society
Review
Highly recurrent CBS epimutations in gastric cancer CpG island methylator phenotypes and inflammation
N Padmanabhan, HK Kyon, A Boot, K Lim, S Srivastava, S Chen, Z Wu, ...
Genome biology 22, 1-29, 2021
Mandates: US National Institutes of Health, National Medical Research Council, Singapore
Review
Evidence for genetic association between chromosome 1q loci and predisposition to colorectal neoplasia
SA Schubert, D Ruano, FA Elsayed, A Boot, S Crobach, AF Sarasqueta, ...
British journal of cancer 117 (8), 1215-1223, 2017
Mandates: Cancer Research UK, UK Medical Research Council, National Institute for …
Review
Toward clinical understanding of aristolochic acid upper-tract urothelial carcinoma
A Boot, N Jiang, SG Rozen
Theranostics 10 (12), 5578, 2020
Mandates: National Medical Research Council, Singapore, Ministry of Health, Singapore
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