Thin-Film Hydration Followed by Extrusion Method for Liposome Preparation H Zhang Methods In Molecular Biology 1522, 17-22, 2017 | 485 | 2017 |
Several rAAV vectors efficiently cross the blood–brain barrier and transduce neurons and astrocytes in the neonatal mouse central nervous system H Zhang, B Yang, X Mu, SS Ahmed, Q Su, R He, H Wang, C Mueller, ... Molecular Therapy 19 (8), 1440-1448, 2011 | 341 | 2011 |
Global CNS transduction of adult mice by intravenously delivered rAAVrh. 8 and rAAVrh. 10 and nonhuman primates by rAAVrh. 10 B Yang, S Li, H Wang, Y Guo, DJ Gessler, C Cao, Q Su, J Kramer, ... Molecular Therapy 22 (7), 1299-1309, 2014 | 252 | 2014 |
Long-term, efficient inhibition of microRNA function in mice using rAAV vectors J Xie, SL Ameres, R Friedline, JH Hung, Y Zhang, Q Xie, L Zhong, Q Su, ... Nature Methods, 2012 | 234 | 2012 |
MicroRNA-regulated, systemically delivered rAAV9: a step closer to CNS-restricted transgene expression J Xie, Q Xie, H Zhang, SL Ameres, JH Hung, Q Su, R He, X Mu, ... Molecular therapy 19 (3), 526-535, 2011 | 201 | 2011 |
CNS targeting AAV vectors and methods of use thereof G Gao, H Zhang, H Wang, Z Xu US Patent 9,102,949, 2015 | 176 | 2015 |
In vivo delivery of CRISPR-Cas9 therapeutics: Progress and challenges M Behr, J Zhou, B Xu, H Zhang Acta Pharmaceutica Sinica B 11 (8), 2150-2171, 2021 | 155 | 2021 |
CNS targeting AAV vectors and methods of use thereof G Gao, H Zhang, H Wang, Z Xu US Patent 9,701,984, 2017 | 105 | 2017 |
A single intravenous rAAV injection as late as P20 achieves efficacious and sustained CNS Gene therapy in Canavan mice SS Ahmed, H Li, C Cao, EM Sikoglu, AR Denninger, Q Su, S Eaton, ... Molecular therapy 21 (12), 2136-2147, 2013 | 98 | 2013 |
Adenovirus–adeno-associated virus hybrid for large-scale recombinant adeno-associated virus production H Zhang, J Xie, Q Xie, JM Wilson, G Gao Human gene therapy 20 (9), 922-929, 2009 | 61 | 2009 |
Short biodegradable polyamines for gene delivery and transfection of brain capillary endothelial cells H Zhang, SV Vinogradov Journal of controlled release 143 (3), 359-366, 2010 | 59 | 2010 |
Efficient transfection of blood− brain barrier endothelial cells by lipoplexes and polyplexes in the presence of nuclear targeting NLS-PEG-acridine conjugates H Zhang, A Mitin, SV Vinogradov Bioconjugate Chemistry 20 (1), 120-128, 2009 | 40 | 2009 |
Liposomes: methods and protocols H Zhang Springer, 2017 | 33 | 2017 |
Multifunctional peptide-PEG intercalating conjugates: programmatic of gene delivery to the blood-brain barrier H Zhang, T Gerson, ML Varney, RK Singh, SV Vinogradov Pharmaceutical research 27, 2528-2543, 2010 | 33 | 2010 |
Cytosolic delivery of the immunological adjuvant Poly I: C and cytotoxic drug crystals via a carrier-free strategy significantly amplifies immune response X Du, Y Hou, J Huang, Y Pang, C Ruan, W Wu, C Xu, H Zhang, L Yin, ... Acta Pharmaceutica Sinica B 11 (10), 3272-3285, 2021 | 29 | 2021 |
Enzymatic noncovalent synthesis for mitochondrial genetic engineering of cancer cells H He, X Lin, D Wu, J Wang, J Guo, DR Green, H Zhang, B Xu Cell Reports Physical Science 1 (12), 2020 | 20 | 2020 |
CNS targeting AAV vectors and methods of use thereof G Gao, H Zhang, H Wang, Z Xu US Patent 10,731,178, 2020 | 20 | 2020 |
Successful transfection of hepatoma cells after encapsulation of plasmid DNA into negatively charged liposomes HW Zhang, L Zhang, X Sun, ZR Zhang Biotechnology and bioengineering 96 (1), 118-124, 2007 | 20 | 2007 |
Growth inhibition of the pulmonary metastatic tumors by systemic delivery of the p27kip1 gene using lyophilized lipid‐polycation‐DNA complexes X Sun, HW Zhang, ZR Zhang The Journal of Gene Medicine: A cross‐disciplinary journal for research on …, 2009 | 16 | 2009 |
Transfection efficiency of pORF lacZ plasmid lipopolyplex to hepatocytes and hepatoma cells X Sun, HW Zhang, ZR Zhang World Journal of Gastroenterology 10 (4), 531, 2004 | 16 | 2004 |