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Hans Cools
Hans Cools
Verified email at syngenta.com
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Year
Finished Genome of the Fungal Wheat Pathogen Mycosphaerella graminicola Reveals Dispensome Structure, Chromosome Plasticity, and Stealth Pathogenesis
SB Goodwin, S Ben M'Barek, B Dhillon, AHJ Wittenberg, CF Crane, ...
PLoS genetics 7 (6), e1002070, 2011
5712011
Update on mechanisms of azole resistance in Mycosphaerella graminicola and implications for future control
HJ Cools, BA Fraaije
Pest management science 69 (2), 150-155, 2013
2972013
Role of ascospores in further spread of QoI-resistant cytochrome b alleles (G143A) in field populations of Mycosphaerella graminicola
BA Fraaije, HJ Cools, J Fountaine, DJ Lovell, J Motteram, JS West, ...
Phytopathology 95 (8), 933-941, 2005
2762005
Risk assessment studies on succinate dehydrogenase inhibitors, the new weapons in the battle to control Septoria leaf blotch in wheat
BA Fraaije, C Bayon, S Atkins, HJ Cools, JA Lucas, MW Fraaije
Molecular Plant Pathology 13 (3), 263-275, 2012
2272012
Overexpression of the sterol 14α‐demethylase gene (MgCYP51) in Mycosphaerella graminicola isolates confers a novel azole fungicide sensitivity phenotype
HJ Cools, C Bayon, S Atkins, JA Lucas, BA Fraaije
Pest management science 68 (7), 1034-1040, 2012
1922012
A novel substitution I381V in the sterol 14α‐demethylase (CYP51) of Mycosphaerella graminicola is differentially selected by azole fungicides
BA Fraaije, HJ Cools, SH Kim, J Motteram, WS Clark, JA Lucas
Molecular plant pathology 8 (3), 245-254, 2007
1832007
Are azole fungicides losing ground against Septoria wheat disease? Resistance mechanisms in Mycosphaerella graminicola
HJ Cools, BA Fraaije
Pest Management Science: Formerly Pesticide Science 64 (7), 681-684, 2008
1812008
Characterization of the sterol 14α‐demethylases of Fusarium graminearum identifies a novel genus‐specific CYP51 function
J Fan, M Urban, JE Parker, HC Brewer, SL Kelly, KE Hammond‐Kosack, ...
New Phytologist 198 (3), 821-835, 2013
1802013
Constraints on the evolution of azole resistance in plant pathogenic fungi
HJ Cools, NJ Hawkins, BA Fraaije
Plant Pathology 62, 36-42, 2013
1592013
Impact of recently emerged sterol 14α-demethylase (CYP51) variants of Mycosphaerella graminicola on azole fungicide sensitivity
HJ Cools, JGL Mullins, BA Fraaije, JE Parker, DE Kelly, JA Lucas, ...
Applied and environmental microbiology 77 (11), 3830-3837, 2011
1542011
Pre-treatment of cucumber plants with acibenzolar-S-methyl systemically primes a phenylalanine ammonia lyase gene (PAL1) for enhanced expression upon attack with a pathogenic …
HJ Cools, H Ishii
Physiological and Molecular Plant Pathology 61 (5), 273-280, 2002
1242002
Mechanism of Binding of Prothioconazole to Mycosphaerella graminicola CYP51 Differs from That of Other Azole Antifungals
JE Parker, AGS Warrilow, HJ Cools, CM Martel, WD Nes, BA Fraaije, ...
Applied and environmental microbiology 77 (4), 1460-1465, 2011
1092011
Heterologous Expression of Mutated Eburicol 14α-Demethylase (CYP51) Proteins of Mycosphaerella graminicola To Assess Effects on Azole Fungicide Sensitivity …
HJ Cools, JE Parker, DE Kelly, JA Lucas, BA Fraaije, SL Kelly
Applied and Environmental Microbiology 76 (9), 2866-2872, 2010
1062010
Molecular modelling of the emergence of azole resistance in Mycosphaerella graminicola
JGL Mullins, JE Parker, HJ Cools, RC Togawa, JA Lucas, BA Fraaije, ...
PloS one 6 (6), e20973, 2011
1052011
Paralog re-emergence: a novel, historically contingent mechanism in the evolution of antimicrobial resistance
NJ Hawkins, HJ Cools, H Sierotzki, MW Shaw, W Knogge, SL Kelly, ...
Molecular Biology and Evolution 31 (7), 1793-1802, 2014
992014
Prothioconazole and prothioconazole-desthio activities against Candida albicans sterol 14-α-demethylase
JE Parker, AGS Warrilow, HJ Cools, BA Fraaije, JA Lucas, K Rigdova, ...
Applied and environmental microbiology 79 (5), 1639-1645, 2013
932013
Proposal for a unified nomenclature for target‐site mutations associated with resistance to fungicides
W Mair, F Lopez‐Ruiz, G Stammler, W Clark, F Burnett, D Hollomon, ...
Pest management science 72 (8), 1449-1459, 2016
862016
Exploitation of genomics in fungicide research: current status and future perspectives
HJ Cools, KE Hammond‐Kosack
Molecular plant pathology 14 (2), 197-210, 2013
802013
Alterations in the predicted regulatory and coding regions of the sterol 14α‐demethylase gene (CYP51) confer decreased azole sensitivity in the oilseed rape pathogen P …
HE Carter, BA Fraaije, JS West, SL Kelly, A Mehl, MW Shaw, HJ Cools
Molecular plant pathology 15 (5), 513-522, 2014
722014
Menadione sodium bisulphite: a novel plant defence activator which enhances local and systemic resistance to infection by Leptosphaeria maculans in oilseed rape
AA Borges, HJ Cools, JA Lucas
Plant Pathology 52 (4), 429-436, 2003
682003
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