Strategies for bypassing the membrane barrier in multidrug resistant Gram-negative bacteria JM Bolla, S Alibert-Franco, J Handzlik, J Chevalier, A Mahamoud, ... FEBS letters 585 (11), 1682-1690, 2011 | 308 | 2011 |
Recent Advances in Multi-Drug Resistance (MDR) Efflux Pump Inhibitors of Gram-Positive Bacteria S. aureus J Handzlik, A Matys, K Kieć-Kononowicz Antibiotics 2 (1), 28-45, 2013 | 191 | 2013 |
Anticancer thiopyrano [2, 3-d][1, 3] thiazol-2-ones with norbornane moiety. Synthesis, cytotoxicity, physico-chemical properties, and computational studies R Lesyk, B Zimenkovsky, D Atamanyuk, F Jensen, K Kieć-Kononowicz, ... Bioorganic & medicinal chemistry 14 (15), 5230-5240, 2006 | 142 | 2006 |
Synthesis of 5-arylidene-2-amino-4-azolones and evaluation of their anticancer activity I Subtel’na, D Atamanyuk, E Szymańska, K Kieć-Kononowicz, ... Bioorganic & medicinal chemistry 18 (14), 5090-5102, 2010 | 128 | 2010 |
Antimycobacterial activity of 5-arylidene derivatives of hydantoin K Kieć-Kononowicz, E Szymańska Il Farmaco 57 (11), 909-916, 2002 | 99 | 2002 |
Molecular and functional interaction between GPR18 and cannabinoid CB2 G-protein-coupled receptors. Relevance in neurodegenerative diseases I Reyes-Resina, G Navarro, D Aguinaga, EI Canela, CT Schoeder, ... Biochemical pharmacology 157, 169-179, 2018 | 78 | 2018 |
The histamine H3R antagonist DL77 attenuates autistic behaviors in a prenatal valproic acid-induced mouse model of autism N Eissa, P Jayaprakash, S Azimullah, SK Ojha, M Al-Houqani, FY Jalal, ... Scientific reports 8 (1), 13077, 2018 | 78 | 2018 |
Synthesis and evaluation of in vivo activity of diphenylhydantoin basic derivatives T Dyla, M Zygmunt, D Macia, J Handzlik, M Bednarski, B Filipek, ... European journal of medicinal chemistry 39 (12), 1013-1027, 2004 | 73 | 2004 |
Natural selenium particles from Staphylococcus carnosus: Hazards or particles with particular promise? EC Estevam, S Griffin, MJ Nasim, P Denezhkin, R Schneider, R Lilischkis, ... Journal of hazardous materials 324, 22-30, 2017 | 70 | 2017 |
Amine–alkyl derivatives of hydantoin: New tool to combat resistant bacteria J Handzlik, E Szymańska, J Chevalier, E Otrębska, K Kieć-Kononowicz, ... European journal of medicinal chemistry 46 (12), 5807-5816, 2011 | 67 | 2011 |
Identification of selenocompounds with promising properties to reverse cancer multidrug resistance E Domínguez-Álvarez, M Gajdács, G Spengler, JA Palop, MA Marć, ... Bioorganic & medicinal chemistry letters 26 (12), 2821-2824, 2016 | 66 | 2016 |
Recent advances in histamine H3 receptor antagonists/inverse agonists D Łażewska, K Kieć-Kononowicz Expert Opinion on Therapeutic Patents 20 (9), 1147-1169, 2010 | 64 | 2010 |
Antimycobacterial activity of 5-arylidene aromatic derivatives of hydantoin E Szymańska, K Kieć-Kononowicz Il Farmaco 57 (5), 355-362, 2002 | 62 | 2002 |
Design, synthesis and biological evaluation of new hybrid anticonvulsants derived from N-benzyl-2-(2, 5-dioxopyrrolidin-1-yl) propanamide and 2-(2, 5-dioxopyrrolidin-1-yl … K Kamiński, A Rapacz, JJ Łuszczki, G Latacz, J Obniska, ... Bioorganic & Medicinal Chemistry 23 (10), 2548-2561, 2015 | 61 | 2015 |
Antimicrobial activity of 5-arylidene aromatic derivatives of hydantoin. Part 2 E Szymańska, K Kieć-Kononowicz, A Białecka, A Kasprowicz Il Farmaco 57 (1), 39-44, 2002 | 61 | 2002 |
Synthesis, α1-adrenoceptor antagonist activity, and SAR study of novel arylpiperazine derivatives of phenytoin J Handzlik, D Maciąg, M Kubacka, S Mogilski, B Filipek, K Stadnicka, ... Bioorganic & medicinal chemistry 16 (11), 5982-5998, 2008 | 56 | 2008 |
The dual-active histamine H3 receptor antagonist and acetylcholine esterase inhibitor E100 ameliorates stereotyped repetitive behavior and neuroinflammmation in sodium … N Eissa, S Azimullah, P Jayaprakash, RL Jayaraj, D Reiner, SK Ojha, ... Chemico-biological interactions 312, 108775, 2019 | 55 | 2019 |
Ether derivatives of 3-piperidinopropan-1-ol as non-imidazole histamine H3 receptor antagonists D Łażewska, X Ligneau, JC Schwartz, W Schunack, H Stark, ... Bioorganic & medicinal chemistry 14 (10), 3522-3529, 2006 | 55 | 2006 |
Aryl-1, 3, 5-triazine derivatives as histamine H4 receptor ligands D Łażewska, M Więcek, J Ner, K Kamińska, T Kottke, JS Schwed, ... European Journal of Medicinal Chemistry 83, 534-546, 2014 | 52 | 2014 |
Biological activity of hydantoin derivatives on P-glycoprotein (ABCB1) of mouse lymphoma cells G Spengler, M Evaristo, J Handzlik, J Serly, J Molnar, M Viveiros, ... Anticancer Research 30 (12), 4867-4871, 2010 | 52 | 2010 |