A time-and cost-efficient system for high-level protein production in mammalian cells AR Aricescu, W Lu, EY Jones Acta Crystallographica Section D: Biological Crystallography 62 (10), 1243-1250, 2006 | 875 | 2006 |
Crystal structure of a human GABAA receptor PS Miller, AR Aricescu Nature 512 (7514), 270-275, 2014 | 821 | 2014 |
Single-particle cryo-EM at atomic resolution T Nakane, A Kotecha, A Sente, G McMullan, S Masiulis, PMGE Brown, ... Nature 587 (7832), 152-156, 2020 | 775 | 2020 |
GABAA receptor signalling mechanisms revealed by structural pharmacology S Masiulis, R Desai, T Uchański, I Serna Martin, D Laverty, D Karia, ... Nature 565 (7740), 454-459, 2019 | 501 | 2019 |
Factors influencing success of clinical genome sequencing across a broad spectrum of disorders JC Taylor, HC Martin, S Lise, J Broxholme, JB Cazier, A Rimmer, ... Nature genetics 47 (7), 717-726, 2015 | 425 | 2015 |
Proteoglycan-specific molecular switch for RPTPσ clustering and neuronal extension CH Coles, Y Shen, AP Tenney, C Siebold, GC Sutton, W Lu, JT Gallagher, ... Science 332 (6028), 484-488, 2011 | 369 | 2011 |
Glycoprotein structural genomics: solving the glycosylation problem VT Chang, M Crispin, AR Aricescu, DJ Harvey, JE Nettleship, JA Fennelly, ... Structure 15 (3), 267-273, 2007 | 346 | 2007 |
Initiation of T cell signaling by CD45 segregation at'close contacts' VT Chang, RA Fernandes, KA Ganzinger, SF Lee, C Siebold, J McColl, ... Nature immunology 17 (5), 574-582, 2016 | 316 | 2016 |
Cryo-EM structure of the human α1β3γ2 GABAA receptor in a lipid bilayer D Laverty, R Desai, T Uchański, S Masiulis, WJ Stec, T Malinauskas, ... Nature 565 (7740), 516-520, 2019 | 309 | 2019 |
Heparan sulfate proteoglycans are ligands for receptor protein tyrosine phosphatase σ AR Aricescu, IW McKinnell, W Halfter, AW Stoker Molecular and cellular biology 22 (6), 1881-1892, 2002 | 271 | 2002 |
Atomic-resolution monitoring of protein maturation in live human cells by NMR L Banci, L Barbieri, I Bertini, E Luchinat, E Secci, Y Zhao, AR Aricescu Nature chemical biology 9 (5), 297-299, 2013 | 250 | 2013 |
An extracellular steric seeding mechanism for Eph-ephrin signaling platform assembly E Seiradake, K Harlos, G Sutton, AR Aricescu, EY Jones Nature structural & molecular biology 17 (4), 398-402, 2010 | 244 | 2010 |
Structural basis of Nipah and Hendra virus attachment to their cell-surface receptor ephrin-B2 TA Bowden, AR Aricescu, RJC Gilbert, JM Grimes, EY Jones, DI Stuart Nature structural & molecular biology 15 (6), 567-572, 2008 | 234 | 2008 |
Lentiviral transduction of mammalian cells for fast, scalable and high-level production of soluble and membrane proteins J Elegheert, E Behiels, B Bishop, S Scott, RE Woolley, SC Griffiths, ... Nature protocols 13 (12), 2991-3017, 2018 | 186 | 2018 |
Structural basis for GABAA receptor potentiation by neurosteroids PS Miller, S Scott, S Masiulis, L De Colibus, E Pardon, J Steyaert, ... Nature structural & molecular biology 24 (11), 986-992, 2017 | 185 | 2017 |
Protein tyrosine phosphatases: structure–function relationships L Tabernero, AR Aricescu, EY Jones, SE Szedlacsek The FEBS journal 275 (5), 867-882, 2008 | 183 | 2008 |
Astrocyte-secreted glypican 4 regulates release of neuronal pentraxin 1 from axons to induce functional synapse formation I Farhy-Tselnicker, ACM van Casteren, A Lee, VT Chang, AR Aricescu, ... Neuron 96 (2), 428-445. e13, 2017 | 180 | 2017 |
Modular mechanism of Wnt signaling inhibition by Wnt inhibitory factor 1 T Malinauskas, AR Aricescu, W Lu, C Siebold, EY Jones Nature structural & molecular biology 18 (8), 886-893, 2011 | 178 | 2011 |
Anterograde C1ql1 signaling is required in order to determine and maintain a single-winner climbing fiber in the mouse cerebellum W Kakegawa, N Mitakidis, E Miura, M Abe, K Matsuda, YH Takeo, ... Neuron 85 (2), 316-329, 2015 | 167 | 2015 |
Immunoglobulin superfamily cell adhesion molecules: zippers and signals AR Aricescu, EY Jones Current opinion in cell biology 19 (5), 543-550, 2007 | 166 | 2007 |