Identification of long noncoding RNA H19 as a new biomarker and therapeutic target in right ventricular failure in pulmonary arterial hypertension J Omura, K Habbout, T Shimauchi, WH Wu, S Breuils-Bonnet, E Tremblay, ... Circulation 142 (15), 1464-1484, 2020 | 125 | 2020 |
Basigin mediates pulmonary hypertension by promoting inflammation and vascular smooth muscle cell proliferation K Satoh, T Satoh, N Kikuchi, J Omura, R Kurosawa, K Suzuki, K Sugimura, ... Circulation research 115 (8), 738-750, 2014 | 116 | 2014 |
Protective roles of endothelial AMP-activated protein kinase against hypoxia-induced pulmonary hypertension in mice J Omura, K Satoh, N Kikuchi, T Satoh, R Kurosawa, M Nogi, T Otsuki, ... Circulation research 119 (2), 197-209, 2016 | 107 | 2016 |
Selenoprotein P promotes the development of pulmonary arterial hypertension: possible novel therapeutic target N Kikuchi, K Satoh, R Kurosawa, N Yaoita, M Elias-Al-Mamun, ... Circulation 138 (6), 600-623, 2018 | 101 | 2018 |
Long-term dietary nitrite and nitrate deficiency causes the metabolic syndrome, endothelial dysfunction and cardiovascular death in mice M Kina-Tanada, M Sakanashi, A Tanimoto, T Kaname, T Matsuzaki, ... Diabetologia 60, 1138-1151, 2017 | 95 | 2017 |
Metabolic syndrome exacerbates pulmonary hypertension due to left heart disease B Ranchoux, V Nadeau, A Bourgeois, S Provencher, É Tremblay, ... Circulation research 125 (4), 449-466, 2019 | 90 | 2019 |
Crucial role of Rho-kinase in pressure overload–induced right ventricular hypertrophy and dysfunction in mice S Ikeda, K Satoh, N Kikuchi, S Miyata, K Suzuki, J Omura, T Shimizu, ... Arteriosclerosis, thrombosis, and vascular biology 34 (6), 1260-1271, 2014 | 86 | 2014 |
Different roles of myocardial ROCK1 and ROCK2 in cardiac dysfunction and postcapillary pulmonary hypertension in mice S Sunamura, K Satoh, R Kurosawa, T Ohtsuki, N Kikuchi, ... Proceedings of the National Academy of Sciences 115 (30), E7129-E7138, 2018 | 83 | 2018 |
17β-Estradiol and estrogen receptor α protect right ventricular function in pulmonary hypertension via BMPR2 and apelin AL Frump, M Albrecht, B Yakubov, S Breuils-Bonnet, V Nadeau, ... The Journal of clinical investigation 131 (6), 2021 | 72 | 2021 |
ADAMTS8 promotes the development of pulmonary arterial hypertension and right ventricular failure: a possible novel therapeutic target J Omura, K Satoh, N Kikuchi, T Satoh, R Kurosawa, M Nogi, T Ohtsuki, ... Circulation research 125 (10), 884-906, 2019 | 59 | 2019 |
Basigin promotes cardiac fibrosis and failure in response to chronic pressure overload in mice K Suzuki, K Satoh, S Ikeda, S Sunamura, T Otsuki, T Satoh, N Kikuchi, ... Arteriosclerosis, thrombosis, and vascular biology 36 (4), 636-646, 2016 | 54 | 2016 |
Pulmonary arterial hypertension: New pathophysiological insights and emerging therapeutic targets A Bourgeois, J Omura, K Habbout, S Bonnet, O Boucherat The international journal of biochemistry & cell biology 104, 9-13, 2018 | 53 | 2018 |
Activated TAFI promotes the development of chronic thromboembolic pulmonary hypertension: a possible novel therapeutic target T Satoh, K Satoh, N Yaoita, N Kikuchi, J Omura, R Kurosawa, K Numano, ... Circulation Research 120 (8), 1246-1262, 2017 | 50 | 2017 |
Prognostic impacts of plasma levels of cyclophilin A in patients with coronary artery disease T Ohtsuki, K Satoh, J Omura, N Kikuchi, T Satoh, R Kurosawa, M Nogi, ... Arteriosclerosis, thrombosis, and vascular biology 37 (4), 685-693, 2017 | 49 | 2017 |
Identification of adipsin as a novel prognostic biomarker in patients with coronary artery disease T Ohtsuki, K Satoh, T Shimizu, S Ikeda, N Kikuchi, T Satoh, R Kurosawa, ... Journal of the American Heart Association 8 (23), e013716, 2019 | 44 | 2019 |
Small GTP-binding protein GDP dissociation stimulator prevents thoracic aortic aneurysm formation and rupture by phenotypic preservation of aortic smooth muscle cells M Nogi, K Satoh, S Sunamura, N Kikuchi, T Satoh, R Kurosawa, J Omura, ... Circulation 138 (21), 2413-2433, 2018 | 44 | 2018 |
Identification of celastramycin as a novel therapeutic agent for pulmonary arterial hypertension: high-throughput screening of 5562 compounds R Kurosawa, K Satoh, N Kikuchi, H Kikuchi, D Saigusa, ME Al-Mamun, ... Circulation research 125 (3), 309-327, 2019 | 42 | 2019 |
SmgGDS as a crucial mediator of the inhibitory effects of statins on cardiac hypertrophy and fibrosis: novel mechanism of the pleiotropic effects of statins S Kudo, K Satoh, M Nogi, K Suzuki, S Sunamura, J Omura, N Kikuchi, ... Hypertension 67 (5), 878-889, 2016 | 40 | 2016 |
PARP1-PKM2 axis mediates right ventricular failure associated with pulmonary arterial hypertension T Shimauchi, O Boucherat, T Yokokawa, Y Grobs, WH Wu, M Orcholski, ... Basic to Translational Science 7 (4), 384-403, 2022 | 28 | 2022 |
Identification of emetine as a therapeutic agent for pulmonary arterial hypertension: novel effects of an old drug MAH Siddique, K Satoh, R Kurosawa, N Kikuchi, M Elias-Al-Mamun, ... Arteriosclerosis, Thrombosis, and Vascular Biology 39 (11), 2367-2385, 2019 | 28 | 2019 |