Human umbilical cord blood–derived mesenchymal stem cells undergo cellular senescence in response to oxidative stress E Ko, KY Lee, DS Hwang Stem cells and development 21 (11), 1877-1886, 2012 | 139 | 2012 |
The MCM8-MCM9 complex promotes RAD51 recruitment at DNA damage sites to facilitate homologous recombination J Park, DT Long, KY Lee, T Abbas, E Shibata, M Negishi, Y Luo, ... Molecular and cellular biology, 2013 | 129 | 2013 |
A new lncRNA, APTR, associates with and represses the CDKN1A/p21 promoter by recruiting polycomb proteins M Negishi, SP Wongpalee, S Sarkar, J Park, KY Lee, Y Shibata, BJ Reon, ... PLoS One 9 (4), e95216, 2014 | 101 | 2014 |
MCM8-9 complex promotes resection of double-strand break ends by MRE11-RAD50-NBS1 complex KY Lee, JS Im, E Shibata, J Park, N Handa, SC Kowalczykowski, A Dutta Nature communications 6 (1), 7744, 2015 | 90 | 2015 |
TopBP1 deficiency causes an early embryonic lethality and induces cellular senescence in primary cells Y Jeon, E Ko, KY Lee, MJ Ko, SY Park, J Kang, CH Jeon, H Lee, ... Journal of Biological Chemistry 286 (7), 5414-5422, 2011 | 80 | 2011 |
Targeted CRISPR screening identifies PRMT5 as synthetic lethality combinatorial target with gemcitabine in pancreatic cancer cells X Wei, J Yang, SJ Adair, H Ozturk, C Kuscu, KY Lee, WJ Kane, PE O’Hara, ... Proceedings of the National Academy of Sciences 117 (45), 28068-28079, 2020 | 67 | 2020 |
Phosphorylation of ORC2 protein dissociates origin recognition complex from chromatin and replication origins KY Lee, SW Bang, SW Yoon, SH Lee, JB Yoon, DS Hwang Journal of Biological Chemistry 287 (15), 11891-11898, 2012 | 61 | 2012 |
The deubiquitinase USP46 is essential for proliferation and tumor growth of HPV-transformed cancers S Kiran, A Dar, SK Singh, KY Lee, A Dutta Molecular cell 72 (5), 823-835. e5, 2018 | 53 | 2018 |
Human TopBP1 participates in cyclin E/CDK2 activation and preinitiation complex assembly during G1/S transition Y Jeon, KY Lee, MJ Ko, YS Lee, S Kang, DS Hwang Journal of Biological Chemistry 282 (20), 14882-14890, 2007 | 50 | 2007 |
ASF1a promotes non-homologous end joining repair by facilitating phosphorylation of MDC1 by ATM at double-strand breaks KY Lee, JS Im, E Shibata, A Dutta Molecular cell 68 (1), 61-75. e5, 2017 | 44 | 2017 |
ATR checkpoint kinase and CRL1βTRCP collaborate to degrade ASF1a and thus repress genes overlapping with clusters of stalled replication forks JS Im, M Keaton, KY Lee, P Kumar, J Park, A Dutta Genes & development 28 (8), 875-887, 2014 | 35 | 2014 |
The pan-cancer landscape of prognostic germline variants in 10,582 patients A Chatrath, R Przanowska, S Kiran, Z Su, S Saha, B Wilson, ... Genome medicine 12, 1-18, 2020 | 29 | 2020 |
Dimeric configuration of SeqA protein bound to a pair of hemi-methylated GATC sequences S Kang, JS Han, KP Kim, HY Yang, KY Lee, CB Hong, DS Hwang Nucleic acids research 33 (5), 1524-1531, 2005 | 26 | 2005 |
Chk1 promotes non-homologous end joining in G1 through direct phosphorylation of ASF1A KY Lee, A Dutta Cell reports 34 (4), 2021 | 12 | 2021 |
Dephosphorylation of Orc2 by protein phosphatase 1 promotes the binding of the origin recognition complex to chromatin KY Lee, JS Bae, S Yoon, DS Hwang Biochemical and Biophysical Research Communications 448 (4), 385-389, 2014 | 10 | 2014 |
Human Primpol1: a novel guardian of stalled replication forks JS Im, KY Lee, LW Dillon, A Dutta EMBO reports 14 (12), 1032-1033, 2013 | 8 | 2013 |
Protein phosphatase 1 dephosphorylates Orc2 KY Lee, JS Bae, GS Kim, DS Hwang Biochemical and Biophysical Research Communications 447 (3), 437-440, 2014 | 4 | 2014 |
Initiation of replication in Xenopus egg extracts at a spatially defined origin KY Lee, A Dutta Cell Cycle 14 (15), 2391-2391, 2015 | | 2015 |