End‐to‐end continuous manufacturing of pharmaceuticals: integrated synthesis, purification, and final dosage formation S Mascia, PL Heider, H Zhang, R Lakerveld, B Benyahia, PI Barton, ... Angewandte Chemie 125 (47), 12585-12589, 2013 | 709 | 2013 |
Membrane-based, liquid–liquid separator with integrated pressure control A Adamo, PL Heider, N Weeranoppanant, KF Jensen Industrial & Engineering Chemistry Research 52 (31), 10802-10808, 2013 | 204 | 2013 |
Development of a multi-step synthesis and workup sequence for an integrated, continuous manufacturing process of a pharmaceutical PL Heider, SC Born, S Basak, B Benyahia, R Lakerveld, H Zhang, ... Organic Process Research & Development 18 (3), 402-409, 2014 | 187 | 2014 |
Rapid flow‐based peptide synthesis MD Simon, PL Heider, A Adamo, AA Vinogradov, SK Mong, X Li, T Berger, ... ChemBioChem 15 (5), 713-720, 2014 | 176 | 2014 |
A Teflon microreactor with integrated piezoelectric actuator to handle solid forming reactions S Kuhn, T Noël, L Gu, PL Heider, KF Jensen Lab on a Chip 11 (15), 2488-2492, 2011 | 164 | 2011 |
The application of an automated control strategy for an integrated continuous pharmaceutical pilot plant R Lakerveld, B Benyahia, PL Heider, H Zhang, A Wolfe, CJ Testa, ... Organic Process Research & Development 19 (9), 1088-1100, 2015 | 105 | 2015 |
Application of continuous crystallization in an integrated continuous pharmaceutical pilot plant H Zhang, R Lakerveld, PL Heider, M Tao, M Su, CJ Testa, AN D’Antonio, ... Crystal growth & design 14 (5), 2148-2157, 2014 | 89 | 2014 |
Selective precipitation‐assisted recovery of immunoglobulins from bovine serum using controlled‐fouling crossflow membrane microfiltration A Venkiteshwaran, P Heider, L Teysseyre, G Belfort Biotechnology and bioengineering 101 (5), 957-966, 2008 | 45 | 2008 |
B, Jamison TF, Jensen KF, Myerson AS, Trout BL S Mascia, PL Heider, H Zhang, R Lakerveld, B Benyahia, PI Barton, ... Angew. Chem. Int. Ed 52, 12359, 2013 | 44 | 2013 |
Reconfiguration of a Continuous Flow Platform for Extended Operation: Application to a Cryogenic Fluorine-Directed ortho-Lithiation Reaction JA Newby, DW Blaylock, PM Witt, RM Turner, PL Heider, BH Harji, ... Organic Process Research & Development 18 (10), 1221-1228, 2014 | 38 | 2014 |
Solid phase peptide synthesis processes and associated systems MD Simon, BL Pentelute, A Adamo, PL Heider, KF Jensen US Patent 9,169,287, 2015 | 33 | 2015 |
Averaging level control to reduce off-spec material in a continuous pharmaceutical pilot plant R Lakerveld, B Benyahia, PL Heider, H Zhang, RD Braatz, PI Barton Processes 1 (3), 330-348, 2013 | 22 | 2013 |
Optimized Removal of Soluble Host Cell Proteins for the Recovery of met‐Human Growth Hormone Inclusion Bodies from Escherichia coli Cell Lysate Using … A Venkiteshwaran, P Heider, S Matosevic, A Bogsnes, A Staby, ... Biotechnology progress 23 (3), 667-672, 2007 | 21 | 2007 |
Solid phase peptides synthesis processes and associated systems MD Simon, BL Pentelute, A Adamo, PL Heider, KF Jensen US Patent 9,868,759, 2018 | 17 | 2018 |
Solid phase peptide synthesis methods and associated systems DA Thomas III, AJ Mijalis, BL Pentelute, MD Simon, A Adamo, PL Heider, ... US Patent App. 15/267,995, 2017 | 15 | 2017 |
Solid phase peptide synthesis processes and associated systems MD Simon, BL Pentelute, A Adamo, PL Heider, KF Jensen US Patent 10,988,504, 2021 | 14 | 2021 |
Solid phase peptide synthesis processes and associated systems MD Simon, BL Pentelute, A Adamo, PL Heider, KF Jensen US Patent 10,889,613, 2021 | 13 | 2021 |
Flow electrochemical cyclizations via amidyl radicals: easy access to cyclic ureas N Ahmed, A Vgenopoulou SynOpen 3 (01), 46-48, 2019 | 12 | 2019 |
Continuous-flow synthesis of tramadol from cyclohexanone TM Monos, JN Jaworski, JC Stephens, TF Jamison Synlett 31 (19), 1888-1893, 2020 | 11 | 2020 |
Development of a Scalable Process for the Insecticidal Candidate Tyclopyrazoflor. Part 3. A Scalable Synthesis of Methyl 3-((3, 3, 3-Trifluoropropyl) thio) propanoate via Thiol … KC Gray, P Heider, P McGough, M Ondari, J Devaraj, Q Yang, G Frycek, ... Organic Process Research & Development 23 (10), 2142-2147, 2019 | 11 | 2019 |