Encoded self-assembling chemical libraries S Melkko, J Scheuermann, CE Dumelin, D Neri Nature biotechnology 22 (5), 568-574, 2004 | 378 | 2004 |
A portable albumin binder from a DNA‐encoded chemical library CE Dumelin, S Trüssel, F Buller, E Trachsel, F Bootz, Y Zhang, ... Angewandte Chemie 120 (17), 3240-3245, 2008 | 252 | 2008 |
High-throughput sequencing allows the identification of binding molecules isolated from DNA-encoded chemical libraries L Mannocci, Y Zhang, J Scheuermann, M Leimbacher, G De Bellis, ... Proceedings of the National Academy of Sciences 105 (46), 17670-17675, 2008 | 247 | 2008 |
DNA-encoded chemical libraries: advancing beyond conventional small-molecule libraries RM Franzini, D Neri, J Scheuermann Accounts of chemical research 47 (4), 1247-1255, 2014 | 240 | 2014 |
Dual-display of small molecules enables the discovery of ligand pairs and facilitates affinity maturation M Wichert, N Krall, W Decurtins, RM Franzini, F Pretto, P Schneider, ... Nature chemistry 7 (3), 241-249, 2015 | 209 | 2015 |
Small targeted cytotoxics: current state and promises from DNA‐encoded chemical libraries N Krall, J Scheuermann, D Neri Angewandte Chemie International Edition 52 (5), 1384-1402, 2013 | 199 | 2013 |
A traceless vascular‐targeting antibody–drug conjugate for cancer therapy GJL Bernardes, G Casi, S Trüssel, I Hartmann, K Schwager, ... Angewandte Chemie International Edition 51 (4), 941-944, 2012 | 164 | 2012 |
20 years of DNA-encoded chemical libraries L Mannocci, M Leimbacher, M Wichert, J Scheuermann, D Neri Chemical communications 47 (48), 12747-12753, 2011 | 161 | 2011 |
A small-molecule inhibitor of Lin28 M Roos, U Pradère, RP Ngondo, A Behera, S Allegrini, G Civenni, ... ACS chemical biology 11 (10), 2773-2781, 2016 | 158 | 2016 |
DNA‐encoded chemical libraries–achievements and remaining challenges N Favalli, G Bassi, J Scheuermann, D Neri FEBS letters 592 (12), 2168-2180, 2018 | 148 | 2018 |
Selection of carbonic anhydrase IX inhibitors from one million DNA-encoded compounds F Buller, M Steiner, K Frey, D Mircsof, J Scheuermann, M Kalisch, ... ACS chemical biology 6 (4), 336-344, 2011 | 147 | 2011 |
Discovery of TNF inhibitors from a DNA-encoded chemical library based on diels-alder cycloaddition F Buller, Y Zhang, J Scheuermann, J Schäfer, P Bühlmann, D Neri Chemistry & biology 16 (10), 1075-1086, 2009 | 147 | 2009 |
Site-specific traceless coupling of potent cytotoxic drugs to recombinant antibodies for pharmacodelivery G Casi, N Huguenin-Dezot, K Zuberbühler, J Scheuermann, D Neri Journal of the American Chemical Society 134 (13), 5887-5892, 2012 | 145 | 2012 |
Design and synthesis of a novel DNA-encoded chemical library using Diels-Alder cycloadditions F Buller, L Mannocci, Y Zhang, CE Dumelin, J Scheuermann, D Neri Bioorganic & medicinal chemistry letters 18 (22), 5926-5931, 2008 | 132 | 2008 |
Automated screening for small organic ligands using DNA-encoded chemical libraries W Decurtins, M Wichert, RM Franzini, F Buller, MA Stravs, Y Zhang, D Neri, ... Nature protocols 11 (4), 764-780, 2016 | 129 | 2016 |
Versatile protein recognition by the encoded display of multiple chemical elements on a constant macrocyclic scaffold Y Li, R De Luca, S Cazzamalli, F Pretto, D Bajic, J Scheuermann, D Neri Nature chemistry 10 (4), 441-448, 2018 | 121 | 2018 |
Isolation of high‐affinity trypsin inhibitors from a DNA‐encoded chemical library S Melkko, Y Zhang, CE Dumelin, J Scheuermann, D Neri Angewandte Chemie 119 (25), 4755-4758, 2007 | 119 | 2007 |
Optimized reaction conditions for amide bond formation in DNA-encoded combinatorial libraries Y Li, E Gabriele, F Samain, N Favalli, F Sladojevich, J Scheuermann, ... ACS combinatorial science 18 (8), 438-443, 2016 | 115 | 2016 |
Discovery of small‐molecule interleukin‐2 inhibitors from a DNA‐encoded chemical library M Leimbacher, Y Zhang, L Mannocci, M Stravs, T Geppert, ... Chemistry–A European Journal 18 (25), 7729-7737, 2012 | 113 | 2012 |
Identification of Structure–Activity Relationships from Screening a Structurally Compact DNA‐Encoded Chemical Library RM Franzini, T Ekblad, N Zhong, M Wichert, W Decurtins, A Nauer, ... Angewandte Chemie 127 (13), 3999-4003, 2015 | 105 | 2015 |