Chemistry of boryllithium: synthesis, structure, and reactivity Y Segawa, Y Suzuki, M Yamashita, K Nozaki Journal of the American Chemical Society 130 (47), 16069-16079, 2008 | 351 | 2008 |
Synthesis, structure of borylmagnesium, and its reaction with benzaldehyde to form benzoylborane M Yamashita, Y Suzuki, Y Segawa, K Nozaki Journal of the American Chemical Society 129 (31), 9570-9571, 2007 | 222 | 2007 |
Telomeric repeat-containing RNA structure in living cells Y Xu, Y Suzuki, K Ito, M Komiyama Proceedings of the National Academy of Sciences 107 (33), 14579-14584, 2010 | 214 | 2010 |
Difference in the lipid nanoparticle technology employed in three approved siRNA (Patisiran) and mRNA (COVID-19 vaccine) drugs Y Suzuki, H Ishihara Drug Metabolism and Pharmacokinetics 41, 100424, 2021 | 167 | 2021 |
PEG shedding-rate-dependent blood clearance of PEGylated lipid nanoparticles in mice: faster PEG shedding attenuates anti-PEG IgM production T Suzuki, Y Suzuki, T Hihara, K Kubara, K Kondo, K Hyodo, K Yamazaki, ... International Journal of Pharmaceutics 588, 119792, 2020 | 107 | 2020 |
Click Chemistry for the Identification of G‐Quadruplex Structures: Discovery of a DNA–RNA G‐Quadruplex Y Xu, Y Suzuki, M Komiyama Angewandte Chemie 121 (18), 3331-3334, 2009 | 89 | 2009 |
Crystal structure of boryllithium with two THF molecules and DFT analysis of its property as a boryl anion M Yamashita, Y Suzuki, Y Segawa, K Nozaki Chemistry letters 37 (7), 802-803, 2008 | 67 | 2008 |
siRNA-lipid nanoparticles with long-term storage stability facilitate potent gene-silencing in vivo Y Suzuki, K Hyodo, Y Tanaka, H Ishihara Journal of Controlled Release 220, 44-50, 2015 | 65 | 2015 |
Human telomeric DNA sequence-specific cleaving by G-quadruplex formation Y Xu, Y Suzuki, T Lönnberg, M Komiyama Journal of the American Chemical Society 131 (8), 2871-2874, 2009 | 63 | 2009 |
Biodegradable lipid nanoparticles induce a prolonged RNA interference-mediated protein knockdown and show rapid hepatic clearance in mice and nonhuman primates Y Suzuki, K Hyodo, T Suzuki, Y Tanaka, H Kikuchi, H Ishihara International Journal of Pharmaceutics 519 (1-2), 34-43, 2017 | 56 | 2017 |
Structure, activity and uptake mechanism of siRNA-lipid nanoparticles with an asymmetric ionizable lipid Y Suzuki, H Ishihara International journal of pharmaceutics 510 (1), 350-358, 2016 | 45 | 2016 |
Design and lyophilization of lipid nanoparticles for mRNA vaccine and its robust immune response in mice and nonhuman primates Y Suzuki, T Miyazaki, H Muto, K Kubara, Y Mukai, R Watari, S Sato, ... Molecular Therapy-Nucleic Acids 30, 226-240, 2022 | 30 | 2022 |
Prompt site-selective DNA hydrolysis by Ce (iv)–EDTA using oligonucleotide multiphosphonate conjugates T Lönnberg, Y Suzuki, M Komiyama Organic & Biomolecular Chemistry 6 (19), 3580-3587, 2008 | 23 | 2008 |
Finding a human telomere DNA–RNA hybrid G-quadruplex formed by human telomeric 6-mer RNA and 16-mer DNA using click chemistry: A protective structure for telomere end Y Xu, Y Suzuki, T Ishizuka, CD Xiao, X Liu, T Hayashi, M Komiyama Bioorganic & Medicinal Chemistry 22 (16), 4419-4421, 2014 | 20 | 2014 |
A 6-mer photocontrolled oligonucleotide as an effective telomerase inhibitor Y Xu, K Ito, Y Suzuki, M Komiyama Journal of the American Chemical Society 132 (2), 631-637, 2010 | 19 | 2010 |
Lipid nanoparticle-targeted mRNA formulation as a treatment for ornithine-transcarbamylase deficiency model mice K Yamazaki, K Kubara, S Ishii, K Kondo, Y Suzuki, T Miyazaki, ... Molecular Therapy-Nucleic Acids 33, 210-226, 2023 | 16 | 2023 |
A novel approach to a fine particle coating using porous spherical silica as core particles M Ishida, J Uchiyama, K Isaji, Y Suzuki, Y Ikematsu, S Aoki Drug Development and Industrial Pharmacy 40 (8), 1054-1064, 2014 | 15 | 2014 |
Irf5 siRNA-loaded biodegradable lipid nanoparticles ameliorate concanavalin A-induced liver injury W Kawase, D Kurotaki, Y Suzuki, H Ishihara, T Ban, GR Sato, J Ichikawa, ... Molecular Therapy-Nucleic Acids 25, 708-715, 2021 | 12 | 2021 |
Differences and similarities of the Intravenously administered lipid nanoparticles in three clinical trials: potential linkage between lipid nanoparticles and extracellular … Y Suzuki, Y Katsurada, K Hyodo Molecular Pharmaceutics 20 (10), 4883-4892, 2023 | 9 | 2023 |
Novel complement C5 small-interfering RNA lipid nanoparticle prolongs graft survival in a hypersensitized rat kidney transplant model H Ishigooka, H Katsumata, K Saiga, D Tokita, S Motoi, C Matsui, Y Suzuki, ... Transplantation 106 (12), 2338-2347, 2022 | 7 | 2022 |