Insulator dysfunction and oncogene activation in IDH mutant gliomas WA Flavahan, Y Drier, BB Liau, SM Gillespie, AS Venteicher, ... Nature 529 (7584), 110-114, 2016 | 1320 | 2016 |
Adaptive chromatin remodeling drives glioblastoma stem cell plasticity and drug tolerance BB Liau, C Sievers, LK Donohue, SM Gillespie, WA Flavahan, TE Miller, ... Cell stem cell 20 (2), 233-246. e7, 2017 | 502 | 2017 |
Mediator kinase inhibition further activates super-enhancer-associated genes in AML HE Pelish, BB Liau, II Nitulescu, A Tangpeerachaikul, ZC Poss, ... Nature 526 (7572), 273-276, 2015 | 374 | 2015 |
Transcription elongation factors represent in vivo cancer dependencies in glioblastoma TE Miller, BB Liau, LC Wallace, AR Morton, Q Xie, D Dixit, DC Factor, ... Nature 547 (7663), 355-359, 2017 | 199 | 2017 |
A multiplexed system for quantitative comparisons of chromatin landscapes P van Galen, AD Viny, O Ram, RJH Ryan, MJ Cotton, L Donohue, ... Molecular cell 61 (1), 170-180, 2016 | 132 | 2016 |
Total synthesis of (+)-fastigiatine BB Liau, MD Shair J. Am. Chem. Soc 132, 9594-9595, 2010 | 101 | 2010 |
CRISPR-suppressor scanning reveals a nonenzymatic role of LSD1 in AML ME Vinyard, C Su, AP Siegenfeld, AL Waterbury, AM Freedy, PM Gosavi, ... Nature chemical biology 15 (5), 529-539, 2019 | 97 | 2019 |
A Unified Strategy for the Synthesis of 7-Membered-Ring-Containing Lycopodium Alkaloids AS Lee, BB Liau, MD Shair Journal of the American Chemical Society 136 (38), 13442-13452, 2014 | 71 | 2014 |
RBPJ maintains brain tumor–initiating cells through CDK9-mediated transcriptional elongation Q Xie, Q Wu, L Kim, TE Miller, BB Liau, SC Mack, K Yang, DC Factor, ... The Journal of clinical investigation 126 (7), 2757-2772, 2016 | 60 | 2016 |
Gain-of-function genetic alterations of G9a drive oncogenesis S Kato, QY Weng, ML Insco, KY Chen, S Muralidhar, J Pozniak, JMS Diaz, ... Cancer discovery 10 (7), 980-997, 2020 | 57 | 2020 |
Total syntheses of HMP-Y1, hibarimicinone, and HMP-P1 BB Liau, BC Milgram, MD Shair Journal of the American Chemical Society 134 (40), 16765-16772, 2012 | 54 | 2012 |
Systematic identification of anticancer drug targets reveals a nucleus-to-mitochondria ROS-sensing pathway J Zhang, CM Simpson, J Berner, HB Chong, J Fang, Z Ordulu, ... Cell 186 (11), 2361-2379. e25, 2023 | 53 | 2023 |
Profiling the landscape of drug resistance mutations in neosubstrates to molecular glue degraders PM Gosavi, KC Ngan, MJR Yeo, C Su, J Li, NZ Lue, SM Hoenig, BB Liau ACS Central Science 8 (4), 417-429, 2022 | 40 | 2022 |
Base editor scanning charts the DNMT3A activity landscape NZ Lue, EM Garcia, KC Ngan, C Lee, JG Doench, BB Liau Nature chemical biology 19 (2), 176-186, 2023 | 30 | 2023 |
Versatile synthetic route to cycloheximide and analogues that potently inhibit translation elongation Y Park, Y Koga, C Su, AL Waterbury, CL Johnny, BB Liau Angewandte Chemie 131 (16), 5441-5445, 2019 | 21 | 2019 |
Discovering new biology with drug-resistance alleles AM Freedy, BB Liau Nature chemical biology 17 (12), 1219-1229, 2021 | 19 | 2021 |
Polycomb-lamina antagonism partitions heterochromatin at the nuclear periphery AP Siegenfeld, SA Roseman, H Roh, NZ Lue, CC Wagen, E Zhou, ... Nature Communications 13 (1), 4199, 2022 | 16 | 2022 |
Gram-Scale Synthesis of the A′ B′-Subunit of Angelmicin B BC Milgram, BB Liau, MD Shair Organic letters 13 (24), 6436-6439, 2011 | 13 | 2011 |
Base editor screens for in situ mutational scanning at scale NZ Lue, BB Liau Molecular Cell 83 (13), 2167-2187, 2023 | 12 | 2023 |
Activity-based CRISPR scanning uncovers allostery in DNA methylation maintenance machinery KCH Ngan, SM Hoenig, HS Kwok, NZ Lue, PM Gosavi, DA Tanner, ... Elife 12, e80640, 2023 | 12 | 2023 |