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Brian B. Liau
Brian B. Liau
Verified email at chemistry.harvard.edu - Homepage
Title
Cited by
Cited by
Year
Insulator dysfunction and oncogene activation in IDH mutant gliomas
WA Flavahan, Y Drier, BB Liau, SM Gillespie, AS Venteicher, ...
Nature 529 (7584), 110-114, 2016
13202016
Adaptive chromatin remodeling drives glioblastoma stem cell plasticity and drug tolerance
BB Liau, C Sievers, LK Donohue, SM Gillespie, WA Flavahan, TE Miller, ...
Cell stem cell 20 (2), 233-246. e7, 2017
5022017
Mediator kinase inhibition further activates super-enhancer-associated genes in AML
HE Pelish, BB Liau, II Nitulescu, A Tangpeerachaikul, ZC Poss, ...
Nature 526 (7572), 273-276, 2015
3742015
Transcription elongation factors represent in vivo cancer dependencies in glioblastoma
TE Miller, BB Liau, LC Wallace, AR Morton, Q Xie, D Dixit, DC Factor, ...
Nature 547 (7663), 355-359, 2017
1992017
A multiplexed system for quantitative comparisons of chromatin landscapes
P van Galen, AD Viny, O Ram, RJH Ryan, MJ Cotton, L Donohue, ...
Molecular cell 61 (1), 170-180, 2016
1322016
Total synthesis of (+)-fastigiatine
BB Liau, MD Shair
J. Am. Chem. Soc 132, 9594-9595, 2010
1012010
CRISPR-suppressor scanning reveals a nonenzymatic role of LSD1 in AML
ME Vinyard, C Su, AP Siegenfeld, AL Waterbury, AM Freedy, PM Gosavi, ...
Nature chemical biology 15 (5), 529-539, 2019
972019
A Unified Strategy for the Synthesis of 7-Membered-Ring-Containing Lycopodium Alkaloids
AS Lee, BB Liau, MD Shair
Journal of the American Chemical Society 136 (38), 13442-13452, 2014
712014
RBPJ maintains brain tumor–initiating cells through CDK9-mediated transcriptional elongation
Q Xie, Q Wu, L Kim, TE Miller, BB Liau, SC Mack, K Yang, DC Factor, ...
The Journal of clinical investigation 126 (7), 2757-2772, 2016
602016
Gain-of-function genetic alterations of G9a drive oncogenesis
S Kato, QY Weng, ML Insco, KY Chen, S Muralidhar, J Pozniak, JMS Diaz, ...
Cancer discovery 10 (7), 980-997, 2020
572020
Total syntheses of HMP-Y1, hibarimicinone, and HMP-P1
BB Liau, BC Milgram, MD Shair
Journal of the American Chemical Society 134 (40), 16765-16772, 2012
542012
Systematic identification of anticancer drug targets reveals a nucleus-to-mitochondria ROS-sensing pathway
J Zhang, CM Simpson, J Berner, HB Chong, J Fang, Z Ordulu, ...
Cell 186 (11), 2361-2379. e25, 2023
532023
Profiling the landscape of drug resistance mutations in neosubstrates to molecular glue degraders
PM Gosavi, KC Ngan, MJR Yeo, C Su, J Li, NZ Lue, SM Hoenig, BB Liau
ACS Central Science 8 (4), 417-429, 2022
402022
Base editor scanning charts the DNMT3A activity landscape
NZ Lue, EM Garcia, KC Ngan, C Lee, JG Doench, BB Liau
Nature chemical biology 19 (2), 176-186, 2023
302023
Versatile synthetic route to cycloheximide and analogues that potently inhibit translation elongation
Y Park, Y Koga, C Su, AL Waterbury, CL Johnny, BB Liau
Angewandte Chemie 131 (16), 5441-5445, 2019
212019
Discovering new biology with drug-resistance alleles
AM Freedy, BB Liau
Nature chemical biology 17 (12), 1219-1229, 2021
192021
Polycomb-lamina antagonism partitions heterochromatin at the nuclear periphery
AP Siegenfeld, SA Roseman, H Roh, NZ Lue, CC Wagen, E Zhou, ...
Nature Communications 13 (1), 4199, 2022
162022
Gram-Scale Synthesis of the A′ B′-Subunit of Angelmicin B
BC Milgram, BB Liau, MD Shair
Organic letters 13 (24), 6436-6439, 2011
132011
Base editor screens for in situ mutational scanning at scale
NZ Lue, BB Liau
Molecular Cell 83 (13), 2167-2187, 2023
122023
Activity-based CRISPR scanning uncovers allostery in DNA methylation maintenance machinery
KCH Ngan, SM Hoenig, HS Kwok, NZ Lue, PM Gosavi, DA Tanner, ...
Elife 12, e80640, 2023
122023
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