Folate–vinca alkaloid conjugates for cancer therapy: A structure–activity relationship CP Leamon, IR Vlahov, JA Reddy, M Vetzel, HKR Santhapuram, F You, ... Bioconjugate chemistry 25 (3), 560-568, 2014 | 83 | 2014 |
Reducing undesirable hepatic clearance of a tumor-targeted vinca alkaloid via novel saccharopeptidic modifications CP Leamon, JA Reddy, PJ Klein, IR Vlahov, R Dorton, A Bloomfield, ... Journal of Pharmacology and Experimental Therapeutics 336 (2), 336-343, 2011 | 66 | 2011 |
Pre-clinical evaluation of EC1456, a folate-tubulysin anti-cancer therapeutic JA Reddy, R Dorton, A Bloomfield, M Nelson, C Dircksen, M Vetzel, ... Scientific reports 8 (1), 8943, 2018 | 58 | 2018 |
Preclinical evaluation of bispecific adaptor molecule controlled folate receptor CAR-T cell therapy with special focus on pediatric malignancies YJ Lu, H Chu, LW Wheeler, M Nelson, E Westrick, JF Matthaei, II Cardle, ... Frontiers in oncology 9, 151, 2019 | 53 | 2019 |
Conjugates for treating diseases caused by PSMA expressing cells IR Vlahov, JA Reddy, A Bloomfield, R Dorton, M Nelson, M Vetzel, ... US Patent 9,636,413, 2017 | 34 | 2017 |
Rational combination therapy of vintafolide (EC145) with commonly used chemotherapeutic drugs JA Reddy, R Dorton, A Bloomfield, M Nelson, M Vetzel, J Guan, ... Clinical Cancer Research 20 (8), 2104-2114, 2014 | 33 | 2014 |
Conjugates for treating diseases caused by PSMA expressing cells IR Vlahov, JA Reddy, A Bloomfield, R Dorton, M Nelson, M Vetzel, ... US Patent 9,782,493, 2017 | 28 | 2017 |
Prostate-specific membrane antigen-specific antitumor activity of a self-immolative tubulysin conjugate CP Leamon, JA Reddy, A Bloomfield, R Dorton, M Nelson, M Vetzel, ... Bioconjugate Chemistry 30 (6), 1805-1813, 2019 | 27 | 2019 |
Conjugates for treating diseases caused by psma expressing cells IR Vlahov, JA Reddy, A Bloomfield, R Dorton, M Nelson, M Vetzel, ... US Patent App. 15/245,508, 2016 | 27 | 2016 |
Conjugates for treating diseases caused by psma expressing cells IR Vlahov, JA Reddy, A Bloomfield, R Dorton, M Nelson, M Vetzel, ... US Patent App. 15/245,512, 2016 | 27 | 2016 |
Latent warheads for targeted cancer therapy: Design and synthesis of pro-pyrrolobenzodiazepines and conjugates IR Vlahov, L Qi, PJ Kleindl, HK Santhapuram, A Felten, GL Parham, ... Bioconjugate Chemistry 28 (12), 2921-2931, 2017 | 18 | 2017 |
High levels of expression of P-glycoprotein/multidrug resistance protein result in resistance to vintafolide AD Guertin, J O'Neil, A Stoeck, JA Reddy, R Cristescu, BB Haines, ... Molecular Cancer Therapeutics 15 (8), 1998-2008, 2016 | 15 | 2016 |
Pre-clinical development of EC1456: A potent Folate targeted Tubulysin SMDC JA Reddy, A Bloomfield, M Nelson, R Dorton, M Vetzel, CP Leamon Cancer research 74 (19_Supplement), 832-832, 2014 | 15 | 2014 |
Pre-clinical studies of EC2629, a highly potent folate-receptor-targeted DNA crosslinking agent JA Reddy, M Nelson, C Dircksen, M Vetzel, T Johnson, V Cross, ... Scientific reports 10 (1), 12772, 2020 | 9 | 2020 |
PSMA-specific anti-tumor activity of the targeted-tubulysin conjugate, EC1169. JA Reddy, A Bloomfield, R Dorton, M Nelson, M Vetzel, S Hahn, I Vlahov, ... Cancer research 73 (8_Supplement), 2145-2145, 2013 | 9 | 2013 |
Detecting functional and accessible folate receptor expression in cancer and polycystic kidneys H Chu, JM Shillingford, JA Reddy, E Westrick, M Nelson, EZ Wang, ... Molecular Pharmaceutics 16 (9), 3985-3995, 2019 | 8 | 2019 |
Methods of treating cancer with tubulysin conjugates CP Leamon, JA Reddy, B Nguyen, A Bloomfield, M Nelson, R Dorton US Patent App. 15/514,193, 2017 | 6 | 2017 |
Preclinical evaluation of bispecific adaptor molecule controlled folate receptor CAR-T cell therapy with special focus on pediatric malignancies. Front Oncol. 2019; 9: 151 YJ Lu, H Chu, LW Wheeler, M Nelson, E Westrick, JF Matthaei, II Cardle, ... Go to original source... Go to PubMed, 2019 | 5 | 2019 |
Openness to experience and working alliance: A preliminary report ML Nelson, CS Taylor annual meeting of the American Psychological Association, Toronto, 1993 | 5 | 1993 |
Development and validation of a UPLC–MS/MS method for the novel folate-targeted small molecule drug conjugate EC1456 and its metabolites in tumor homogenates from mice SI Rao, M Pugh, M Nelson, JA Reddy, PJ Klein, CP Leamon Journal of Pharmaceutical and Biomedical Analysis 122, 148-156, 2016 | 4 | 2016 |