Temporal control of neurogenin3 activity in pancreas progenitors reveals competence windows for the generation of different endocrine cell types KA Johansson, U Dursun, N Jordan, G Gu, F Beermann, G Gradwohl, ... Developmental cell 12 (3), 457-465, 2007 | 420 | 2007 |
Endoderm development: from patterning to organogenesis A Grapin-Botton, DA Melton Trends in genetics 16 (3), 124-130, 2000 | 405 | 2000 |
Key events of pancreas formation are triggered in gut endoderm by ectopic expression of pancreatic regulatory genes A Grapin-Botton, AR Majithia, DA Melton Genes & development 15 (4), 444-454, 2001 | 367 | 2001 |
Artificial three-dimensional niches deconstruct pancreas development in vitro C Greggio, F De Franceschi, M Figueiredo-Larsen, S Gobaa, A Ranga, ... Development 140 (21), 4452-4462, 2013 | 314 | 2013 |
Signals from lateral plate mesoderm instruct endoderm toward a pancreatic fate M Kumar, N Jordan, D Melton, A Grapin-Botton Developmental biology 259 (1), 109-122, 2003 | 304 | 2003 |
Determination of the identity of the derivatives of the cephalic neural crest: incompatibility between Hox gene expression and lower jaw development G Couly, A Grapin-Botton, P Coltey, B Ruhin, NML Douarin Development 125 (17), 3445-3459, 1998 | 289 | 1998 |
A Notch-dependent molecular circuitry initiates pancreatic endocrine and ductal cell differentiation HP Shih, JL Kopp, M Sandhu, CL Dubois, PA Seymour, A Grapin-Botton, ... Development 139 (14), 2488-2499, 2012 | 268 | 2012 |
FGF signaling is necessary for establishing gut tube domains alongthe anterior–posterior axis in vivo J Dessimoz, R Opoka, JJ Kordich, A Grapin-Botton, JM Wells Mechanisms of development 123 (1), 42-55, 2006 | 247 | 2006 |
Pancreas-specific deletion of β-catenin reveals Wnt-dependent and Wnt-independent functions during development J Dessimoz, C Bonnard, J Huelsken, A Grapin-Botton Current Biology 15 (18), 1677-1683, 2005 | 199 | 2005 |
The regeneration of the cephalic neural crest, a problem revisited: the regenerating cells originate from the contralateral or from the anterior and posterior neural fold G Couly, A Grapin-Botton, P Coltey, NML Douarin Development 122 (11), 3393-3407, 1996 | 196 | 1996 |
Plasticity of transposed rhombomeres: Hox gene induction is correlated with phenotypic modifications A Grapin-Botton, MA Bonnin, LA McNaughton, R Krumlauf, NML Douarin Development 121 (9), 2707-2721, 1995 | 179 | 1995 |
Neurogenin3 initiates stepwise delamination of differentiating endocrine cells during pancreas development M Gouzi, YH Kim, K Katsumoto, K Johansson, A Grapin‐Botton Developmental dynamics 240 (3), 589-604, 2011 | 176 | 2011 |
Ductal cells of the pancreas A Grapin-Botton The international journal of biochemistry & cell biology 37 (3), 504-510, 2005 | 169 | 2005 |
Retinoic acid signaling organizes endodermal organ specification along the entire antero-posterior axis E Bayha, MC Jørgensen, P Serup, A Grapin-Botton PloS one 4 (6), e5845, 2009 | 166 | 2009 |
The molecular and morphogenetic basis of pancreas organogenesis HL Larsen, A Grapin-Botton Seminars in cell & developmental biology 66, 51-68, 2017 | 153 | 2017 |
The EndoC-βH1 cell line is a valid model of human beta cells and applicable for screenings to identify novel drug target candidates VG Tsonkova, FW Sand, XA Wolf, LG Grunnet, AK Ringgaard, ... Molecular metabolism 8, 144-157, 2018 | 138 | 2018 |
The histone demethylase Jmjd3 sequentially associates with the transcription factors Tbx3 and Eomes to drive endoderm differentiation AER Kartikasari, JX Zhou, MS Kanji, DN Chan, A Sinha, A Grapin‐Botton, ... The EMBO journal 32 (10), 1393-1408, 2013 | 122 | 2013 |
The expression pattern of the mafB/kr gene in birds and mice reveals that the kreisler phenotype does not represent a null mutant A Eichmann, A Grapin-Botton, L Kelly, T Graf, NM Le Douarin, M Sieweke Mechanisms of development 65 (1-2), 111-122, 1997 | 114 | 1997 |
Single-cell gene expression analysis of a human ESC model of pancreatic endocrine development reveals different paths to β-cell differentiation MBK Petersen, A Azad, C Ingvorsen, K Hess, M Hansson, ... Stem cell reports 9 (4), 1246-1261, 2017 | 112 | 2017 |
Evolution of the mechanisms and molecular control of endoderm formation A Grapin-Botton, D Constam Mechanisms of development 124 (4), 253-278, 2007 | 107 | 2007 |