Tumor-derived hydrogen sulfide, produced by cystathionine-β-synthase, stimulates bioenergetics, cell proliferation, and angiogenesis in colon cancer C Szabo, C Coletta, C Chao, K Módis, B Szczesny, A Papapetropoulos, ... Proceedings of the National Academy of Sciences 110 (30), 12474-12479, 2013 | 737 | 2013 |
Hydrogen sulfide and nitric oxide are mutually dependent in the regulation of angiogenesis and endothelium-dependent vasorelaxation C Coletta, A Papapetropoulos, K Erdelyi, G Olah, K Módis, P Panopoulos, ... Proceedings of the National Academy of Sciences 109 (23), 9161-9166, 2012 | 728 | 2012 |
Regulation of mitochondrial bioenergetic function by hydrogen sulfide. Part I. Biochemical and physiological mechanisms C Szabo, C Ransy, K Módis, M Andriamihaja, B Murghes, C Coletta, ... British journal of pharmacology 171 (8), 2099-2122, 2014 | 474 | 2014 |
Intramitochondrial hydrogen sulfide production by 3‐mercaptopyruvate sulfurtransferase maintains mitochondrial electron flow and supports cellular bioenergetics K Módis, C Coletta, K Erdélyi, A Papapetropoulos, C Szabo The FASEB Journal 27 (2), 601-611, 2013 | 334 | 2013 |
Hydrogen sulfide replacement therapy protects the vascular endothelium in hyperglycemia by preserving mitochondrial function K Suzuki, G Olah, K Modis, C Coletta, G Kulp, D Gerö, P Szoleczky, ... Proceedings of the National Academy of Sciences 108 (33), 13829-13834, 2011 | 321 | 2011 |
AP39, a novel mitochondria-targeted hydrogen sulfide donor, stimulates cellular bioenergetics, exerts cytoprotective effects and protects against the loss of mitochondrial DNA … B Szczesny, K Módis, K Yanagi, C Coletta, S Le Trionnaire, A Perry, ... Nitric oxide 41, 120-130, 2014 | 291 | 2014 |
S-Sulfhydration of ATP synthase by hydrogen sulfide stimulates mitochondrial bioenergetics K Módis, YJ Ju, A Ahmad, AA Untereiner, Z Altaany, L Wu, C Szabo, ... Pharmacological research 113, 116-124, 2016 | 194 | 2016 |
Cardioprotective effects of hydrogen sulfide G Szabó, G Veres, T Radovits, D Gerő, K Módis, C Miesel-Gröschel, ... Nitric Oxide 25 (2), 201-210, 2011 | 166 | 2011 |
Regulation of mitochondrial bioenergetic function by hydrogen sulfide. Part II. Pathophysiological and therapeutic aspects K Módis, EM Bos, E Calzia, H Van Goor, C Coletta, A Papapetropoulos, ... British journal of pharmacology 171 (8), 2123-2146, 2014 | 152 | 2014 |
Pathophysiological roles of peroxynitrite in circulatory shock C Szabó, K Módis Shock 34 (7), 4-14, 2010 | 150 | 2010 |
Regulation of Vascular Tone, Angiogenesis and Cellular Bioenergetics by the 3-Mercaptopyruvate Sulfurtransferase/H2S Pathway: Functional Impairment by Hyperglycemia … C Coletta, K Módis, B Szczesny, A Brunyánszki, G Oláh, ECS Rios, ... Molecular Medicine 21, 1-14, 2015 | 138 | 2015 |
Role of endogenous and exogenous nitric oxide, carbon monoxide and hydrogen sulfide in HCT116 colon cancer cell proliferation G Oláh, K Módis, G Törö, MR Hellmich, B Szczesny, C Szabo Biochemical pharmacology 149, 186-204, 2018 | 120 | 2018 |
Upregulation of cystathionine-β-synthase in colonic epithelia reprograms metabolism and promotes carcinogenesis CNM Phillips, JR Zatarain, ME Nicholls, C Porter, SG Widen, K Thanki, ... Cancer research 77 (21), 5741-5754, 2017 | 119 | 2017 |
Endothelial dysfunction is a potential contributor to multiple organ failure and mortality in aged mice subjected to septic shock: preclinical studies in a murine model of … C Coletta, K Módis, G Oláh, A Brunyánszki, DS Herzig, ER Sherwood, ... Critical care 18, 1-15, 2014 | 109 | 2014 |
Effect of S-adenosyl-L-methionine (SAM), an allosteric activator of cystathionine-β-synthase (CBS) on colorectal cancer cell proliferation and bioenergetics in vitro K Módis, C Coletta, A Asimakopoulou, B Szczesny, C Chao, ... Nitric oxide 41, 146-156, 2014 | 105 | 2014 |
Hydrogen sulfide-mediated stimulation of mitochondrial electron transport involves inhibition of the mitochondrial phosphodiesterase 2A, elevation of cAMP and activation of … K Módis, P Panopoulos, C Coletta, A Papapetropoulos, C Szabo Biochemical Pharmacology 86 (9), 1311-1319, 2013 | 102 | 2013 |
Oxidative stress suppresses the cellular bioenergetic effect of the 3-mercaptopyruvate sulfurtransferase/hydrogen sulfide pathway K Módis, A Asimakopoulou, C Coletta, A Papapetropoulos, C Szabo Biochemical and Biophysical Research Communications 433 (4), 401-407, 2013 | 98 | 2013 |
Cellular bioenergetics is regulated by PARP1 under resting conditions and during oxidative stress K Módis, D Gerő, K Erdélyi, P Szoleczky, D DeWitt, C Szabo Biochemical pharmacology 83 (5), 633-643, 2012 | 94 | 2012 |
H2S-induced S-sulfhydration of lactate dehydrogenase a (LDHA) stimulates cellular bioenergetics in HCT116 colon cancer cells AA Untereiner, G Oláh, K Módis, MR Hellmich, C Szabo Biochemical pharmacology 136, 86-98, 2017 | 91 | 2017 |
Cystathionine-β-synthase inhibition for colon cancer: enhancement of the efficacy of aminooxyacetic acid via the prodrug approach C Chao, JR Zatarain, Y Ding, C Coletta, AA Mrazek, N Druzhyna, ... Molecular Medicine 22, 361-379, 2016 | 76 | 2016 |