| The SOFA score—development, utility and challenges of accurate assessment in clinical trials S Lambden, PF Laterre, MM Levy, B Francois Critical Care 23, 1-9, 2019 | 815 | 2019 |
| Definitions and pathophysiology of vasoplegic shock S Lambden, BC Creagh-Brown, J Hunt, C Summers, LG Forni Critical Care 22, 1-8, 2018 | 201 | 2018 |
| Observational Skill-based Clinical Assessment tool for Resuscitation (OSCAR): development and validation S Walker, S Brett, A McKay, S Lambden, C Vincent, N Sevdalis Resuscitation 82 (7), 835-844, 2011 | 127 | 2011 |
| Unannounced in situ simulations: integrating training and clinical practice ST Walker, N Sevdalis, A McKay, S Lambden, S Gautama, R Aggarwal, ... BMJ quality & safety 22 (6), 453-458, 2013 | 94 | 2013 |
| Bench to bedside review: therapeutic modulation of nitric oxide in sepsis—an update S Lambden Intensive Care Medicine Experimental 7 (1), 64, 2019 | 68 | 2019 |
| Dimethylarginine dimethylaminohydrolase 2 regulates nitric oxide synthesis and hemodynamics and determines outcome in polymicrobial sepsis S Lambden, P Kelly, B Ahmetaj-Shala, Z Wang, B Lee, M Nandi, ... Arteriosclerosis, Thrombosis, and Vascular Biology 35 (6), 1382-1392, 2015 | 52 | 2015 |
| Pharmacological inhibition of DDAH1 improves survival, haemodynamics and organ function in experimental septic shock Z Wang, S Lambden, V Taylor, E Sujkovic, M Nandi, J Tomlinson, ... Biochemical Journal 460 (2), 309-316, 2014 | 45 | 2014 |
| sTREM-1 is a specific biomarker of TREM-1 pathway activation L Jolly, K Carrasco, M Salcedo-Magguilli, JJ Garaud, S Lambden, ... Cellular & molecular immunology 18 (8), 2054-2056, 2021 | 41 | 2021 |
| Bilateral objective tinnitus secondary to congenital middle-ear myoclonus GD Howsam, A Sharma, SP Lambden, J Fitzgerald, PR Prinsley The Journal of Laryngology & Otology 119 (6), 489-491, 2005 | 37 | 2005 |
| Increased sTREM-1 plasma concentrations are associated with poor clinical outcomes in patients with COVID-19 AH de Nooijer, I Grondman, S Lambden, EJ Kooistra, NAF Janssen, ... Bioscience Reports 41 (7), BSR20210940, 2021 | 27 | 2021 |
| NMDA receptor modulation of glutamate release in activated neutrophils AG Del Arroyo, A Hadjihambi, J Sanchez, E Turovsky, V Kasymov, D Cain, ... EBioMedicine 47, 457-469, 2019 | 25 | 2019 |
| The Imperial Paediatric Emergency Training Toolkit (IPETT) for use in paediatric emergency training: development and evaluation of feasibility and validity S Lambden, C DeMunter, A Dowson, M Cooper, S Gautama, N Sevdalis Resuscitation 84 (6), 831-836, 2013 | 23 | 2013 |
| Prospective evaluation of the efficacy, safety, and optimal biomarker enrichment strategy for nangibotide, a TREM-1 inhibitor, in patients with septic shock (ASTONISH): a … B François, S Lambden, T Fivez, S Gibot, M Derive, JM Grouin, ... The Lancet Respiratory Medicine 11 (10), 894-904, 2023 | 18 | 2023 |
| Challenges in the anesthetic and intensive care management of acute ischemic stroke MA Kirkman, S Lambden, M Smith Journal of neurosurgical anesthesiology 28 (3), 214-232, 2016 | 16 | 2016 |
| Rationale and protocol for the efficacy, safety and tolerability of nangibotide in patients with septic shock (ASTONISH) phase IIb randomised controlled trial B Francois, S Lambden, S Gibot, M Derive, A Olivier, V Cuvier, S Witte, ... BMJ open 11 (7), e042921, 2021 | 14 | 2021 |
| 2-Hydroxyglutarate Metabolism Is Altered in an in vivo Model of LPS Induced Endotoxemia SF Fitzpatrick, S Lambden, D Macias, Z Puthucheary, S Pietsch, L Mendil, ... Frontiers in Physiology 11, 147, 2020 | 13 | 2020 |
| Hypoxia causes increased monocyte nitric oxide synthesis which is mediated by changes in dimethylarginine dimethylaminohydrolase 2 expression in animal and human models of … S Lambden, D Martin, K Vanezis, B Lee, J Tomlinson, S Piper, O Boruc, ... Nitric Oxide 58, 59-66, 2016 | 13 | 2016 |
| The use of computers for perioperative simulation in anesthesia, critical care, and pain medicine S Lambden, B Martin Anesthesiology Clinics 29 (3), 521-531, 2011 | 12 | 2011 |
| Acute intravascular haemolysis associated with intravenous administration of meropenem in a sixty four year old man. SP Lambden, J Akeru, NA Barrett The Canadian Journal of Clinical Pharmacology= Journal Canadien de …, 2010 | 10 | 2010 |
| Evidence for a protective role for the rs805305 single nucleotide polymorphism of dimethylarginine dimethylaminohydrolase 2 (DDAH2) in septic shock through the regulation of … S Lambden, J Tomlinson, S Piper, AC Gordon, J Leiper Critical Care 22, 1-9, 2018 | 9 | 2018 |
Charles VincentProfessor of Psychology, University of OxfordVerified email at psy.ox.ac.uk