Articles with public access mandates - Tudor OpreaLearn more
Not available anywhere: 9
Model-free drug-likeness from fragments
O Ursu, TI Oprea
Journal of chemical information and modeling 50 (8), 1387-1394, 2010
Mandates: US National Institutes of Health
Discovery of a Novel Selective PPARγ Ligand with Partial Agonist Binding Properties by Integrated in Silico/in Vitro Work Flow
I Kouskoumvekaki, RK Petersen, F Fratev, O Taboureau, TE Nielsen, ...
Journal of chemical information and modeling 53 (4), 923-937, 2013
Mandates: Danish Council for Technology and Innovation, Danish Council for Strategic …
Surely you are joking, Mr Docking!
F Gentile, TI Oprea, A Tropsha, A Cherkasov
Chemical Society Reviews 52 (3), 872-878, 2023
Mandates: US National Institutes of Health, Canadian Institutes of Health Research
Off-patent drug repositioning
S Avram, R Curpan, L Halip, A Bora, TI Oprea
Journal of chemical information and modeling 60 (12), 5746-5753, 2020
Mandates: US National Institutes of Health
Drug-like physicochemical properties
PD Leeson, TI Oprea
Mandates: US National Institutes of Health
Understanding virulence mechanisms in M. tuberculosis infection via a circuit-based simulation framework
E May, A Leitao, JL Faulon, J Joo, M Misra, TI Oprea
2008 30th Annual International Conference of the IEEE Engineering in …, 2008
Mandates: US National Institutes of Health
The ontology reference model for visual selectivity analysis in drug-target interactions
Q Cheng, FA Lopez, C Duran, C Camarillo, TI Oprea, S Schurer
2017 IEEE International Conference on Bioinformatics and Biomedicine (BIBM …, 2017
Mandates: US National Institutes of Health, US Department of Education
Learning reference-enriched approach towards large scale active ontology alignment and integration
Q Cheng, O Ursu, TI Oprea, S Schurer
2017 IEEE International Conference on Bioinformatics and Biomedicine (BIBM …, 2017
Mandates: US National Institutes of Health, US Department of Education
Cheminformatics Data Mining and Modeling for Drug Repurposing
S Avram, R Curpan, TI Oprea
Mandates: US National Institutes of Health
Available somewhere: 148
A comprehensive map of molecular drug targets
R Santos, O Ursu, A Gaulton, AP Bento, RS Donadi, CG Bologa, ...
Nature reviews Drug discovery 16 (1), 19-34, 2017
Mandates: US National Institutes of Health, Cancer Research UK, Wellcome Trust
BDDCS, the Rule of 5 and drugability
LZ Benet, CM Hosey, O Ursu, TI Oprea
Advanced drug delivery reviews 101, 89-98, 2016
Mandates: US National Institutes of Health
BDDCS applied to over 900 drugs
LZ Benet, F Broccatelli, TI Oprea
The AAPS journal 13, 519-547, 2011
Mandates: US National Institutes of Health
QSAR without borders
EN Muratov, J Bajorath, RP Sheridan, IV Tetko, D Filimonov, V Poroikov, ...
Chemical Society Reviews 49 (11), 3525-3564, 2020
Mandates: US National Science Foundation, US Department of Defense, US National …
In vivo effects of a GPR30 antagonist
MK Dennis, R Burai, C Ramesh, WK Petrie, SN Alcon, TK Nayak, ...
Nature chemical biology 5 (6), 421-427, 2009
Mandates: US National Institutes of Health
Unexplored therapeutic opportunities in the human genome
TI Oprea, CG Bologa, S Brunak, A Campbell, GN Gan, A Gaulton, ...
Nature reviews Drug discovery 17 (5), 317-332, 2018
Mandates: US National Institutes of Health, European Molecular Biology Laboratory …
Drug repurposing from an academic perspective
TI Oprea, JE Bauman, CG Bologa, T Buranda, A Chigaev, BS Edwards, ...
Drug Discovery Today: Therapeutic Strategies 8 (3-4), 61-69, 2011
Mandates: US National Institutes of Health
How many rare diseases are there?
M Haendel, N Vasilevsky, D Unni, C Bologa, N Harris, H Rehm, ...
Nature reviews drug discovery 19 (2), 77-78, 2020
Mandates: US National Institutes of Health
Novel chemical space exploration via natural products
J Rosén, J Gottfries, S Muresan, A Backlund, TI Oprea
Journal of medicinal chemistry 52 (7), 1953-1962, 2009
Mandates: US National Institutes of Health
Identification of a GPER/GPR30 antagonist with improved estrogen receptor counterselectivity
MK Dennis, AS Field, R Burai, C Ramesh, WK Petrie, CG Bologa, ...
The Journal of steroid biochemistry and molecular biology 127 (3-5), 358-366, 2011
Mandates: US National Institutes of Health
The significance of acid/base properties in drug discovery
DT Manallack, RJ Prankerd, E Yuriev, TI Oprea, DK Chalmers
Chemical Society Reviews 42 (2), 485-496, 2013
Mandates: US National Institutes of Health
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