Template-directed RNA polymerization and enhanced ribozyme catalysis inside membraneless compartments formed by coacervates RR Poudyal, RM Guth-Metzler, AJ Veenis, EA Frankel, CD Keating, ... Nature communications 10 (1), 490, 2019 | 232 | 2019 |
Polyamine/Nucleotide Coacervates Provide Strong Compartmentalization of Mg2+, Nucleotides, and RNA EA Frankel, PC Bevilacqua, CD Keating Langmuir 32 (8), 2041-2049, 2016 | 153 | 2016 |
Cellular conditions of weakly chelated magnesium ions strongly promote RNA stability and catalysis R Yamagami, JL Bingaman, EA Frankel, PC Bevilacqua Nature communications 9 (1), 2149, 2018 | 73 | 2018 |
Cooperative Interactions in the Hammerhead Ribozyme Drive pKa Shifting of G12 and Its Stacked Base C17 EA Frankel, CA Strulson, CD Keating, PC Bevilacqua Biochemistry 56 (20), 2537-2548, 2017 | 35 | 2017 |
Complexity in pH-Dependent Ribozyme Kinetics: Dark pKa Shifts and Wavy Rate–pH Profiles EA Frankel, PC Bevilacqua Biochemistry 57 (5), 483-488, 2018 | 28 | 2018 |
Encapsulation of organic materials in protocells EA Frankel, DC Dewey, CD Keating Astrobiology: An Evolutionary Approach, 217-255, 2014 | 5 | 2014 |
Eliminating blurry bands in gels with a simple cost-effective repair to the gel cassette JL Bingaman, EA Frankel, CM Hull, KA Leamy, KJ Messina, D Mitchell, ... RNA 22 (12), 1929-1930, 2016 | 1 | 2016 |
KEY CATALYTIC STRATEGIES OF RIBOZYMES PC BEVILACQUA, JL BINGAMAN, EA FRANKEL, KJ MESSINA, ... Catalysis In Chemistry And Biology-Proceedings Of The 24th International …, 2018 | | 2018 |
Towards Investigation of RNA Catalysis and Compartmentalization EA Frankel The Pennsylvania State University, 2017 | | 2017 |
Polyamine/nucleotide coacervates strongly partition RNA to mimic early Earth protocells and modern cellular compartments E Frankel, P Bevilacqua, C Keating ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 252, 2016 | | 2016 |
Uncovering catalytic driving forces in the hammerhead ribozyme: Binding of Mg2+ promotes pKa shifting of guanine towards neutrality E Frankel, C Keating, P Bevilacqua ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 251, 2016 | | 2016 |