Extracellular matrix and cell signalling: the dynamic cooperation of integrin, proteoglycan and growth factor receptor. SH Kim, J Turnbull, S Guimond The Journal of endocrinology 209 (2), 139-151, 2011 | 1426 | 2011 |
Activating and inhibitory heparin sequences for FGF-2 (basic FGF). Distinct requirements for FGF-1, FGF-2, and FGF-4. S Guimond, M Maccarana, BB Olwin, U Lindahl, AC Rapraeger Journal of Biological Chemistry 268 (32), 23906-23914, 1993 | 729 | 1993 |
Heparan sulfate: decoding a dynamic multifunctional cell regulator J Turnbull, A Powell, S Guimond Trends in cell biology 11 (2), 75-82, 2001 | 604 | 2001 |
Heparin inhibits cellular invasion by SARS-CoV-2: structural dependence of the interaction of the spike S1 receptor-binding domain with heparin CJ Mycroft-West, D Su, I Pagani, TR Rudd, S Elli, NS Gandhi, ... Thrombosis and haemostasis 120 (12), 1700-1715, 2020 | 310 | 2020 |
Fibroblast growth factor receptor signalling is dictated by specific heparan sulphate saccharides SE Guimond, JE Turnbull Current Biology 9 (22), 1343-1346, 1999 | 242 | 1999 |
The 2019 coronavirus (SARS-CoV-2) surface protein (Spike) S1 Receptor Binding Domain undergoes conformational change upon heparin binding C Mycroft-West, D Su, S Elli, Y Li, S Guimond, G Miller, J Turnbull, E Yates, ... BioRxiv, 2020.02. 29.971093, 2020 | 229 | 2020 |
Anosmin-1 modulates fibroblast growth factor receptor 1 signaling in human gonadotropin-releasing hormone olfactory neuroblasts through a heparan sulfate-dependent mechanism D González-Martínez, SH Kim, Y Hu, S Guimond, J Schofield, P Winyard, ... Journal of Neuroscience 24 (46), 10384-10392, 2004 | 181 | 2004 |
[11] Regulation by heparan sulfate in fibroblast growth factor signaling AC Rapraeger, S Guimond, A Krufka, BB Olwin Methods in enzymology 245, 219-240, 1994 | 143 | 1994 |
Localisation of specific heparan sulfate proteoglycans during the proliferative phase of brain development M Ford‐Perriss, K Turner, S Guimond, A Apedaile, HD Haubeck, ... Developmental dynamics: an official publication of the American Association …, 2003 | 118 | 2003 |
Novel mechanisms of fibroblast growth factor receptor 1 regulation by extracellular matrix protein anosmin-1 Y Hu, SE Guimond, P Travers, S Cadman, E Hohenester, JE Turnbull, ... Journal of Biological Chemistry 284 (43), 29905-29920, 2009 | 94 | 2009 |
Diversification of the structural determinants of fibroblast growth factor-heparin interactions: implications for binding specificity R Xu, A Ori, TR Rudd, KA Uniewicz, YA Ahmed, SE Guimond, ... Journal of Biological Chemistry 287 (47), 40061-40073, 2012 | 92 | 2012 |
Variant heparan sulfates synthesized in developing mouse brain differentially regulate FGF signaling M Ford-Perriss, SE Guimond, U Greferath, M Kita, K Grobe, H Habuchi, ... Glycobiology 12 (11), 721-727, 2002 | 92 | 2002 |
Influence of substitution pattern and cation binding on conformation and activity in heparin derivatives TR Rudd, SE Guimond, MA Skidmore, L Duchesne, M Guerrini, G Torri, ... Glycobiology 17 (9), 983-993, 2007 | 89 | 2007 |
Two hierarchies of FGF-2 signaling in heparin: mitogenic stimulation and high-affinity binding/receptor transphosphorylation A Krufka, S Guimond, AC Rapraeger Biochemistry 35 (34), 11131-11141, 1996 | 89 | 1996 |
Synthetic heparan sulfate mimetic pixatimod (PG545) potently inhibits SARS-CoV-2 by disrupting the spike–ACE2 interaction SE Guimond, CJ Mycroft-West, NS Gandhi, JA Tree, TT Le, CM Spalluto, ... ACS central science 8 (5), 527-545, 2022 | 81 | 2022 |
Disaccharide compositional analysis of heparan sulfate and heparin polysaccharides using UV or high-sensitivity fluorescence (BODIPY) detection MA Skidmore, SE Guimond, AF Dumax-Vorzet, EA Yates, JE Turnbull Nature protocols 5 (12), 1983-1992, 2010 | 74 | 2010 |
High sensitivity separation and detection of heparan sulfate disaccharides MA Skidmore, SE Guimond, AF Dumax-Vorzet, A Atrih, EA Yates, ... Journal of Chromatography A 1135 (1), 52-56, 2006 | 70 | 2006 |
Glycosaminoglycan origin and structure revealed by multivariate analysis of NMR and CD spectra TR Rudd, MA Skidmore, SE Guimond, C Cosentino, G Torri, DG Fernig, ... Glycobiology 19 (1), 52-67, 2009 | 65 | 2009 |
Rapid Purification and High Sensitivity Analysis of Heparan Sulfate from Cells and Tissues: TOWARD GLYCOMICS PROFILING*♦ SE Guimond, TM Puvirajesinghe, MA Skidmore, I Kalus, T Dierks, ... Journal of Biological Chemistry 284 (38), 25714-25722, 2009 | 61 | 2009 |
Differential sulfation remodelling of heparan sulfate by extracellular 6-O-sulfatases regulates fibroblast growth factor-induced boundary formation by glial cells: implications … JR Higginson, SM Thompson, A Santos-Silva, SE Guimond, JE Turnbull, ... Journal of Neuroscience 32 (45), 15902-15912, 2012 | 55 | 2012 |