The human immunoglobulin VH repertoire GP Cook, IM Tomlinson Immunology today 16 (5), 237-242, 1995 | 637 | 1995 |
Primer: inflammasomes and interleukin 1β in inflammatory disorders LD Church, GP Cook, MF McDermott Nature clinical practice Rheumatology 4 (1), 34-42, 2008 | 459 | 2008 |
The requirement for DNAM-1, NKG2D, and NKp46 in the natural killer cell-mediated killing of myeloma cells YM El-Sherbiny, JL Meade, TD Holmes, D McGonagle, SL Mackie, ... Cancer research 67 (18), 8444-8449, 2007 | 402 | 2007 |
A map of the human immunoglobulin VH locus completed by analysis of the telomeric region of chromosome 14q GP Cook, IM Tomlinson, G Walter, H Riethman, NP Carter, L Buluwela, ... Nature Genetics 7 (2), 162-168, 1994 | 326 | 1994 |
A second B cell-specific enhancer 3'of the immunoglobulin heavy-chain locus S Pettersson, GP Cook, M Brüggemann, GT Williams, MS Neuberger Nature 344 (6262), 165-168, 1990 | 313 | 1990 |
Evidence of NLRP3-inflammasome activation in rheumatoid arthritis (RA); genetic variants within the NLRP3-inflammasome complex in relation to susceptibility to RA and response … RJ Mathews, JI Robinson, M Battellino, C Wong, JC Taylor, S Eyre, ... Annals of the rheumatic diseases 73 (6), 1202-1210, 2014 | 224* | 2014 |
Human tumour immune evasion via TGF-β blocks NK cell activation but not survival allowing therapeutic restoration of anti-tumour activity EB Wilson, JJ El-Jawhari, AL Neilson, GD Hall, AA Melcher, JL Meade, ... PloS one 6 (9), e22842, 2011 | 194 | 2011 |
Organization of the human immunoglobulin lambda light-chain locus on chromosome 22q11. 2 JP Fippiat, SC Williams, LM Tomlinson, GP Cook, D Cherif, DL Paslier, ... Human Molecular Genetics 4 (6), 983-991, 1995 | 162 | 1995 |
Antibody repertoires of four-and five-feature translocus mice carrying human immunoglobulin heavy chain and κ and λ light chain yeast artificial chromosomes IC Nicholson, X Zou, AV Popov, GP Cook, EM Corps, S Humphries, ... The Journal of Immunology 163 (12), 6898-6906, 1999 | 155 | 1999 |
Creation of mice expressing human antibody light chains by introduction of a yeast artificial chromosome containing the core region of the human immunoglobulin κ locus NP Davies, IR Rosewell, JC Richardson, GP Cook, MS Neuberger, ... Bio/Technology 11 (8), 911-914, 1993 | 136 | 1993 |
Human immunoglobulin VH and D segments on chromosomes 15q11. 2 and 16p11. 2 MT Ian, GP Cook, PC Nigel, R Elaswarapu, S Smith, G Walter, L Buluwela, ... Human molecular genetics 3 (6), 853-860, 1994 | 108 | 1994 |
A family with Papillon-Lefevre syndrome reveals a requirement for cathepsin C in granzyme B activation and NK cell cytolytic activity JL Meade, EA de Wynter, P Brett, SM Sharif, CG Woods, AF Markham, ... Blood 107 (9), 3665-3668, 2006 | 105 | 2006 |
β-Catenin–mediated immune evasion pathway frequently operates in primary cutaneous melanomas J Nsengimana, J Laye, A Filia, S O’Shea, S Muralidhar, J Poźniak, ... The Journal of clinical investigation 128 (5), 2048-2063, 2018 | 91 | 2018 |
High-risk human papillomavirus E7 expression reduces cell-surface MHC class I molecules and increases susceptibility to natural killer cells G Bottley, OG Watherston, YL Hiew, B Norrild, GP Cook, GE Blair Oncogene 27 (12), 1794-1799, 2008 | 85 | 2008 |
MAFA‐L, an ITIM‐containing receptor encoded by the human NK cell gene complex and expressed by basophils and NK cells S Butcher, KL Arney, GP Cook European journal of immunology 28 (11), 3755-3762, 1998 | 85 | 1998 |
Licensed human natural killer cells aid dendritic cell maturation via TNFSF14/LIGHT TD Holmes, EB Wilson, EVI Black, AV Benest, C Vaz, B Tan, VM Tanavde, ... Proceedings of the National Academy of Sciences 111 (52), E5688-E5696, 2014 | 83 | 2014 |
TLR dependent XBP-1 activation induces an autocrine loop in rheumatoid arthritis synoviocytes S Savic, L Ouboussad, LJ Dickie, J Geiler, C Wong, GM Doody, ... Journal of autoimmunity 50, 59-66, 2014 | 80 | 2014 |
A human NK cell activation/inhibition threshold allows small changes in the target cell surface phenotype to dramatically alter susceptibility to NK cells TD Holmes, YM El-Sherbiny, A Davison, SL Clough, GE Blair, GP Cook The Journal of Immunology 186 (3), 1538-1545, 2011 | 78 | 2011 |
Cytotoxic and immune‐mediated killing of human colorectal cancer by reovirus‐loaded blood and liver mononuclear cells RA Adair, KJ Scott, S Fraser, F Errington‐Mais, H Pandha, M Coffey, ... International journal of cancer 132 (10), 2327-2338, 2013 | 77 | 2013 |
Safety and clinical effect of subcutaneous human interleukin-21 in patients with metastatic melanoma or renal cell carcinoma: a phase I trial H Schmidt, J Brown, U Mouritzen, P Selby, K Fode, IM Svane, GP Cook, ... Clinical Cancer Research 16 (21), 5312-5319, 2010 | 70 | 2010 |