Lactate influx through the endothelial cell monocarboxylate transporter MCT1 supports an NF-κB/IL-8 pathway that drives tumor angiogenesis F Végran, R Boidot, C Michiels, P Sonveaux, O Feron Cancer research 71 (7), 2550-2560, 2011 | 831 | 2011 |
The receptor NLRP3 is a transcriptional regulator of TH2 differentiation M Bruchard, C Rebé, V Derangère, D Togbé, B Ryffel, R Boidot, ... Nature immunology 16 (8), 859-870, 2015 | 388 | 2015 |
Intestinal Akkermansia muciniphila predicts clinical response to PD-1 blockade in patients with advanced non-small-cell lung cancer L Derosa, B Routy, AM Thomas, V Iebba, G Zalcman, S Friard, J Mazieres, ... Nature medicine 28 (2), 315-324, 2022 | 327 | 2022 |
Cross-reactivity between tumor MHC class I–restricted antigens and an enterococcal bacteriophage A Fluckiger, R Daillère, M Sassi, BS Sixt, P Liu, F Loos, C Richard, ... Science 369 (6506), 936-942, 2020 | 272 | 2020 |
Regulation of monocarboxylate transporter MCT1 expression by p53 mediates inward and outward lactate fluxes in tumors R Boidot, F Végran, A Meulle, A Le Breton, C Dessy, P Sonveaux, ... Cancer research 72 (4), 939-948, 2012 | 270 | 2012 |
Accumulation of MDSC and Th17 cells in patients with metastatic colorectal cancer predicts the efficacy of a FOLFOX–bevacizumab drug treatment regimen E Limagne, R Euvrard, M Thibaudin, C Rébé, V Derangère, A Chevriaux, ... Cancer research 76 (18), 5241-5252, 2016 | 250 | 2016 |
The transcription factor IRF1 dictates the IL-21-dependent anticancer functions of TH9 cells F Végran, H Berger, R Boidot, G Mignot, M Bruchard, M Dosset, ... Nature immunology 15 (8), 758-766, 2014 | 225 | 2014 |
PD-1/PD-L1 pathway: an adaptive immune resistance mechanism to immunogenic chemotherapy in colorectal cancer M Dosset, TR Vargas, A Lagrange, R Boidot, F Végran, A Roussey, ... Oncoimmunology 7 (6), e1433981, 2018 | 195 | 2018 |
Tumor infiltration by Tbet+ effector T cells and CD20+ B cells is associated with survival in gastric cancer patients A Hennequin, V Derangere, R Boidot, L Apetoh, J Vincent, D Orry, ... Oncoimmunology 5 (2), e1054598, 2016 | 194 | 2016 |
Transcriptome-wide identification of transient RNA G-quadruplexes in human cells SY Yang, P Lejault, S Chevrier, R Boidot, AG Robertson, JMY Wong, ... Nature Communications 9 (1), 4730, 2018 | 191 | 2018 |
Optimized fractionated radiotherapy with anti-PD-L1 and anti-TIGIT: a promising new combination M Grapin, C Richard, E Limagne, R Boidot, V Morgand, A Bertaut, ... Journal for immunotherapy of cancer 7, 1-12, 2019 | 182 | 2019 |
Prognostic and predictive role of CD8 and PD-L1 determination in lung tumor tissue of patients under anti-PD-1 therapy JD Fumet, C Richard, F Ledys, Q Klopfenstein, P Joubert, B Routy, ... British journal of cancer 119 (8), 950-960, 2018 | 150 | 2018 |
A natural polyphenol exerts antitumor activity and circumvents anti–PD-1 resistance through effects on the gut microbiota M Messaoudene, R Pidgeon, C Richard, M Ponce, K Diop, M Benlaifaoui, ... Cancer Discovery 12 (4), 1070-1087, 2022 | 122 | 2022 |
Sirtuin-1 activation controls tumor growth by impeding Th17 differentiation via STAT3 deacetylation E Limagne, M Thibaudin, R Euvrard, H Berger, P Chalons, F Végan, ... Cell reports 19 (4), 746-759, 2017 | 121 | 2017 |
Antibiotic use does not appear to influence response to nivolumab C Kaderbhai, C Richard, JD Fumet, A Aarnink, P Foucher, B Coudert, ... Anticancer research 37 (6), 3195-3200, 2017 | 113 | 2017 |
Association of p53 gene alterations with the expression of antiapoptotic survivin splice variants in breast cancer F Vegran, R Boidot, C Oudin, C Defrain, M Rebucci, S Lizard-Nacol Oncogene 26 (2), 290-297, 2007 | 99 | 2007 |
Transcriptional regulation of the survivin gene R Boidot, F Végran, S Lizard-Nacol Molecular biology reports 41, 233-240, 2014 | 98 | 2014 |
Overexpression of caspase-3s splice variant in locally advanced breast carcinoma is associated with poor response to neoadjuvant chemotherapy F Végran, R Boidot, C Oudin, JM Riedinger, F Bonnetain, S Lizard-Nacol Clinical cancer research 12 (19), 5794-5800, 2006 | 89 | 2006 |
Distinct expression of Survivin splice variants in breast carcinomas F Vegran, R Boidot, C Oudin, JM Riedinger, S Lizard-Nacol International journal of oncology 27 (4), 1151-1157, 2005 | 86 | 2005 |
Cleaved caspase-3 transcriptionally regulates angiogenesis-promoting chemotherapy resistance A Bernard, S Chevrier, F Beltjens, M Dosset, E Viltard, A Lagrange, ... Cancer research 79 (23), 5958-5970, 2019 | 80 | 2019 |