Targeting C-reactive protein for the treatment of cardiovascular disease MB Pepys, GM Hirschfield, GA Tennent, J Ruth Gallimore, MC Kahan, ... Nature 440 (7088), 1217-1221, 2006 | 907 | 2006 |
Pharmacological characterization of bosentan, a new potent orally active nonpeptide endothelin receptor antagonist. M Clozel, V Breu, GA Gray, B Kalina, BM Löffler, K Burri, JM Cassal, ... Journal of Pharmacology and Experimental Therapeutics 270 (1), 228-235, 1994 | 855 | 1994 |
Loss of vascular responsiveness induced by endotoxin involves L-arginine pathway G Julou-Schaeffer, GA Gray, I Fleming, C Schott, JR Parratt, JC Stoclet American Journal of Physiology-Heart and Circulatory Physiology 259 (4 …, 1990 | 678 | 1990 |
Pathophysiological role of endothelin revealed by the first orally active endothelin receptor antagonist M Clozel, V Breu, K Burri, JM Cassal, W Fischli, GA Gray, G Hirth, ... Nature 365 (6448), 759-761, 1993 | 642 | 1993 |
The endothelin ETB receptor mediates both vasodilation and vasoconstriction in vivo M Clozel, GA Gray, V Breu, BM Löffler, R Osterwalder Biochemical and biophysical research communications 186 (2), 867-873, 1992 | 520 | 1992 |
Differential effects of angiotensin II on cardiac cell proliferation and intramyocardial perivascular fibrosis in vivo PE McEwan, GA Gray, L Sherry, DJ Webb, CJ Kenyon Circulation 98 (24), 2765-2773, 1998 | 256 | 1998 |
Vasodilator Effects of Endothelin-Converting Enzyme Inhibition and Endothelin ETA Receptor Blockade in Chronic Heart Failure Patients Treated With ACE Inhibitors MP Love, WG Haynes, GA Gray, DJ Webb, JJV McMurray Circulation 94 (9), 2131-2137, 1996 | 227 | 1996 |
Incubation with endotoxin activates the L-arginine pathway in vascular tissue I Fleming, GA Gray, G Julou-Schaeffer, JR Parratt, JC Stoclet Biochemical and biophysical research communications 171 (2), 562-568, 1990 | 222 | 1990 |
Deficiency of PDK1 in cardiac muscle results in heart failure and increased sensitivity to hypoxia A Mora, AM Davies, L Bertrand, I Sharif, GR Budas, S Jovanović, ... The EMBO journal, 2003 | 218 | 2003 |
Systemic blockade of the endothelin-B receptor increases peripheral vascular resistance in healthy men FE Strachan, JC Spratt, IB Wilkinson, NR Johnston, GA Gray, DJ Webb Hypertension 33 (1), 581-585, 1999 | 195 | 1999 |
The effect of inhibitors of the l‐arginine/nitric oxide pathway on endotoxin‐induced loss of vascular responsiveness in anaesthetized rats GA Gray, C Schott, G Julou‐Schaeffer, I Fleming, JR Parratt, JC Stoclet British journal of pharmacology 103 (1), 1218-1224, 1991 | 195 | 1991 |
The endothelin system and its potential as a therapeutic target in cardiovascular disease GA Gray, DJ Webb Pharmacology & therapeutics 72 (2), 109-148, 1996 | 193 | 1996 |
Human myocardial pericytes: multipotent mesodermal precursors exhibiting cardiac specificity WCW Chen, JE Baily, M Corselli, ME Díaz, B Sun, G Xiang, GA Gray, ... Stem cells 33 (2), 557-573, 2015 | 182 | 2015 |
Single-cell transcriptome analyses reveal novel targets modulating cardiac neovascularization by resident endothelial cells following myocardial infarction Z Li, EG Solomonidis, M Meloni, RS Taylor, R Duffin, R Dobie, ... European heart journal 40 (30), 2507-2520, 2019 | 178 | 2019 |
Preventing local regeneration of glucocorticoids by 11β-hydroxysteroid dehydrogenase type 1 enhances angiogenesis GR Small, PWF Hadoke, I Sharif, AR Dover, D Armour, CJ Kenyon, ... Proceedings of the National Academy of Sciences 102 (34), 12165-12170, 2005 | 176 | 2005 |
The role of endothelin in experimental cerebral vasospasm S Roux, BM Löffler, GA Gray, U Sprecher, M Clozel, JP Clozel Neurosurgery 37 (1), 78-86, 1995 | 174 | 1995 |
Evidence that an l‐arginine/nitric oxide dependent elevation of tissue cyclic GMP content is involved in depression of vascular reactivity by endotoxin I Fleming, G Julou‐Schaeffer, GA Gray, JR Parratt, JC Stoclet British journal of pharmacology 103 (1), 1047-1052, 1991 | 169 | 1991 |
Inducible but not constitutive production of nitric oxide by vascular smooth muscle cells I Fleming, GA Gray, C Schott, JC Stoclet European journal of pharmacology 200 (2-3), 375-376, 1991 | 136 | 1991 |
Deletion of endothelial cell endothelin B receptors does not affect blood pressure or sensitivity to salt AJ Bagnall, NF Kelland, F Gulliver-Sloan, AP Davenport, GA Gray, ... Hypertension 48 (2), 286-293, 2006 | 131 | 2006 |
Nitric oxide and endotoxemia JC Stoclet, I Fleming, G Gray, G Julou-Schaeffer, F Schneider, C Schott Monograph-American Heart Association 87 (5), V77-V80, 1993 | 122 | 1993 |