Genetic studies of body mass index yield new insights for obesity biology AE Locke, B Kahali, SI Berndt, AE Justice, TH Pers, FR Day, C Powell, ... Nature 518 (7538), 197-206, 2015 | 4786 | 2015 |
A comprehensive 1000 Genomes–based genome-wide association meta-analysis of coronary artery disease Nature genetics 47 (10), 1121-1130, 2015 | 2462 | 2015 |
Defining the role of common variation in the genomic and biological architecture of adult human height AR Wood, T Esko, J Yang, S Vedantam, TH Pers, S Gustafsson, AY Chu, ... Nature genetics 46 (11), 1173-1186, 2014 | 2110 | 2014 |
TGF-β and epithelial-to-mesenchymal transitions J Zavadil, EP Böttinger Oncogene 24 (37), 5764-5774, 2005 | 2108 | 2005 |
Fine-mapping type 2 diabetes loci to single-variant resolution using high-density imputation and islet-specific epigenome maps A Mahajan, D Taliun, M Thurner, NR Robertson, JM Torres, NW Rayner, ... Nature genetics 50 (11), 1505-1513, 2018 | 1647 | 2018 |
Glucose-induced reactive oxygen species cause apoptosis of podocytes and podocyte depletion at the onset of diabetic nephropathy K Susztak, AC Raff, M Schiffer, EP Bottinger Diabetes 55 (1), 225-233, 2006 | 1384 | 2006 |
Defective fatty acid oxidation in renal tubular epithelial cells has a key role in kidney fibrosis development HM Kang, SH Ahn, P Choi, YA Ko, SH Han, F Chinga, ASD Park, J Tao, ... Nature medicine 21 (1), 37-46, 2015 | 1265 | 2015 |
The genetic architecture of type 2 diabetes C Fuchsberger, J Flannick, TM Teslovich, A Mahajan, V Agarwala, ... Nature 536 (7614), 41-47, 2016 | 1260 | 2016 |
Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits E Evangelou, HR Warren, D Mosen-Ansorena, B Mifsud, R Pazoki, H Gao, ... Nature genetics 50 (10), 1412-1425, 2018 | 1240 | 2018 |
TGF-ß signaling in renal disease EP Bo, M Bitzer Journal of the American society of nephrology 13 (10), 2600-2610, 2002 | 1075 | 2002 |
Integration of TGF‐β/Smad and Jagged1/Notch signalling in epithelial‐to‐mesenchymal transition J Zavadil, L Cermak, N Soto‐Nieves, EP Böttinger The EMBO journal 23 (5), 1155-1165, 2004 | 955 | 2004 |
Apoptosis in podocytes induced by TGF-β and Smad7 M Schiffer, M Bitzer, ISD Roberts, JB Kopp, P ten Dijke, P Mundel, ... The Journal of clinical investigation 108 (6), 807-816, 2001 | 843 | 2001 |
Genetic analyses of diverse populations improves discovery for complex traits GL Wojcik, M Graff, KK Nishimura, R Tao, J Haessler, CR Gignoux, ... Nature 570 (7762), 514-518, 2019 | 830 | 2019 |
AKI in hospitalized patients with COVID-19 L Chan, K Chaudhary, A Saha, K Chauhan, A Vaid, S Zhao, I Paranjpe, ... Journal of the American Society of Nephrology 32 (1), 151-160, 2021 | 756 | 2021 |
An expanded genome-wide association study of type 2 diabetes in Europeans RA Scott, LJ Scott, R Mägi, L Marullo, KJ Gaulton, M Kaakinen, ... Diabetes 66 (11), 2888-2902, 2017 | 750 | 2017 |
Genome‐wide molecular profiles of HCV‐induced dysplasia and hepatocellular carcinoma E Wurmbach, Y Chen, G Khitrov, W Zhang, S Roayaie, M Schwartz, I Fiel, ... Hepatology 45 (4), 938-947, 2007 | 737 | 2007 |
Genetic programs of epithelial cell plasticity directed by transforming growth factor-β J Zavadil, M Bitzer, D Liang, YC Yang, A Massimi, S Kneitz, E Piek, ... Proceedings of the National Academy of Sciences 98 (12), 6686-6691, 2001 | 686 | 2001 |
Rare and low-frequency coding variants alter human adult height E Marouli, M Graff, C Medina-Gomez, KS Lo, AR Wood, TR Kjaer, RS Fine, ... Nature 542 (7640), 186-190, 2017 | 664 | 2017 |
Mouse models of diabetic nephropathy MD Breyer, E Bo, FC Brosius III, TM Coffman, RC Harris, CW Heilig, ... Journal of the American Society of Nephrology 16 (1), 27-45, 2005 | 660 | 2005 |
Epigenetic regulation of Foxp3 expression in regulatory T cells by DNA methylation G Lal, N Zhang, W Van Der Touw, Y Ding, W Ju, EP Bottinger, SP Reid, ... The Journal of Immunology 182 (1), 259-273, 2009 | 659 | 2009 |