Atomic view of a toxic amyloid small oligomer A Laganowsky, C Liu, MR Sawaya, JP Whitelegge, J Park, M Zhao, ... Science 335 (6073), 1228-1231, 2012 | 614 | 2012 |
Amyloid fibril structure of α-synuclein determined by cryo-electron microscopy Y Li, C Zhao, F Luo, Z Liu, X Gui, Z Luo, X Zhang, D Li, C Liu, X Li Cell research 28 (9), 897-903, 2018 | 409 | 2018 |
Toxic fibrillar oligomers of amyloid-β have cross-β structure JC Stroud, C Liu, PK Teng, D Eisenberg Proceedings of the National Academy of Sciences 109 (20), 7717-7722, 2012 | 375 | 2012 |
Amyloid β-sheet mimics that antagonize protein aggregation and reduce amyloid toxicity PN Cheng, C Liu, M Zhao, D Eisenberg, JS Nowick Nature chemistry 4 (11), 927-933, 2012 | 261 | 2012 |
Liquid-liquid phase separation in biology: mechanisms, physiological functions and human diseases H Zhang, X Ji, P Li, C Liu, J Lou, Z Wang, W Wen, Y Xiao, M Zhang, X Zhu Science China Life Sciences 63, 953-985, 2020 | 235 | 2020 |
PARylation regulates stress granule dynamics, phase separation, and neurotoxicity of disease-related RNA-binding proteins Y Duan, A Du, J Gu, G Duan, C Wang, X Gui, Z Ma, B Qian, X Deng, ... Cell research 29 (3), 233-247, 2019 | 223 | 2019 |
The structured core domain of αB-crystallin can prevent amyloid fibrillation and associated toxicity GKA Hochberg, H Ecroyd, C Liu, D Cox, D Cascio, MR Sawaya, ... Proceedings of the National Academy of Sciences 111 (16), E1562-E1570, 2014 | 222 | 2014 |
Out-of-register β-sheets suggest a pathway to toxic amyloid aggregates C Liu, M Zhao, L Jiang, PN Cheng, J Park, MR Sawaya, A Pensalfini, ... Proceedings of the National Academy of Sciences, 2012 | 209 | 2012 |
Atomic structures of FUS LC domain segments reveal bases for reversible amyloid fibril formation F Luo, X Gui, H Zhou, J Gu, Y Li, X Liu, M Zhao, D Li, X Li, C Liu Nature structural & molecular biology 25 (4), 341-346, 2018 | 200 | 2018 |
Structural basis for reversible amyloids of hnRNPA1 elucidates their role in stress granule assembly X Gui, F Luo, Y Li, H Zhou, Z Qin, Z Liu, J Gu, M Xie, K Zhao, B Dai, ... Nature communications 10 (1), 2006, 2019 | 180 | 2019 |
Phase Separation of Disease-Associated SHP2 Mutants Underlies MAPK Hyperactivation G Zhu, J Xie, W Kong, J Xie, Y Li, L Du, Q Zheng, L Sun, M Guan, H Li, ... Cell 183 (2), 490-502. e18, 2020 | 172 | 2020 |
Structure-based discovery of fiber-binding compounds that reduce the cytotoxicity of amyloid beta L Jiang, C Liu, D Leibly, M Landau, M Zhao, MP Hughes, DS Eisenberg Elife 2, e00857, 2013 | 154 | 2013 |
Macrocyclic β-sheet peptides that inhibit the aggregation of a tau-protein-derived hexapeptide J Zheng, C Liu, MR Sawaya, B Vadla, S Khan, RJ Woods, D Eisenberg, ... Journal of the American Chemical Society 133 (9), 3144-3157, 2011 | 154 | 2011 |
Parkinson’s disease-related phosphorylation at Tyr39 rearranges α-synuclein amyloid fibril structure revealed by cryo-EM K Zhao, YJ Lim, Z Liu, H Long, Y Sun, JJ Hu, C Zhao, Y Tao, X Zhang, ... Proceedings of the National Academy of Sciences 117 (33), 20305-20315, 2020 | 150 | 2020 |
Stress induces dynamic, cytotoxicity-antagonizing TDP-43 nuclear bodies via paraspeckle lncRNA NEAT1-mediated liquid-liquid phase separation C Wang, Y Duan, G Duan, Q Wang, K Zhang, X Deng, B Qian, J Gu, Z Ma, ... Molecular Cell 79 (3), 443-458. e7, 2020 | 147 | 2020 |
Tunable assembly of amyloid-forming peptides into nanosheets as a retrovirus carrier B Dai, D Li, W Xi, F Luo, X Zhang, M Zou, M Cao, J Hu, W Wang, G Wei, ... Proceedings of the National Academy of Sciences 112 (10), 2996-3001, 2015 | 145 | 2015 |
Hsp27 chaperones FUS phase separation under the modulation of stress-induced phosphorylation Z Liu, S Zhang, J Gu, Y Tong, Y Li, X Gui, H Long, C Wang, C Zhao, J Lu, ... Nature Structural & Molecular Biology 27 (4), 363-372, 2020 | 134 | 2020 |
β 2-microglobulin forms three-dimensional domain-swapped amyloid fibrils with disulfide linkages C Liu, MR Sawaya, D Eisenberg Nature structural & molecular biology 18 (1), 49-55, 2011 | 134 | 2011 |
Cryo-EM structure of an amyloid fibril formed by full-length human prion protein LQ Wang, K Zhao, HY Yuan, Q Wang, Z Guan, J Tao, XN Li, Y Sun, CW Yi, ... Nature Structural & Molecular Biology 27 (6), 598-602, 2020 | 130 | 2020 |
Versatile structures of α-synuclein C Wang, C Zhao, D Li, Z Tian, Y Lai, J Diao, C Liu Frontiers in molecular neuroscience 9, 48, 2016 | 124 | 2016 |