Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ... autophagy 17 (1), 1-382, 2021 | 13466* | 2021 |
HGF receptor associates with the anti‐apoptotic protein BAG‐1 and prevents cell death. A Bardelli, P Longati, D Albero, S Goruppi, C Schneider, C Ponzetto, ... The EMBO journal 15 (22), 6205-6212, 1996 | 404 | 1996 |
Gas6, the ligand of Axl tyrosine kinase receptor, has mitogenic and survival activities for serum starved NIH3T3 fibroblasts. S Goruppi, E Ruaro, C Schneider Oncogene 12 (3), 471-480, 1996 | 326 | 1996 |
Requirement of phosphatidylinositol 3-kinase-dependent pathway and Src for Gas6-Axl mitogenic and survival activities in NIH 3T3 fibroblasts S Goruppi, E Ruaro, B Varnum, C Schneider Molecular and cellular biology, 1997 | 233 | 1997 |
Combined CSL and p53 downregulation promotes cancer-associated fibroblast activation MG Procopio, C Laszlo, D Al Labban, DE Kim, P Bordignon, SH Jo, ... Nature cell biology 17 (9), 1193-1204, 2015 | 218 | 2015 |
Gas6-mediated survival in NIH3T3 cells activates stress signalling cascade and is independent of Ras S Goruppi, E Ruaro, B Varnum, C Schneider Oncogene 18 (29), 4224-4236, 1999 | 147 | 1999 |
Stress-inducible protein p8 is involved in several physiological and pathological processes S Goruppi, JL Iovanna Journal of Biological Chemistry 285 (3), 1577-1581, 2010 | 114 | 2010 |
Signaling pathways and late‐onset gene induction associated with renal mesangial cell hypertrophy S Goruppi, JV Bonventre, JM Kyriakis The EMBO journal, 2002 | 93 | 2002 |
Gas6 induces growth, β-catenin stabilization, and T-cell factor transcriptional activation in contact-inhibited C57 mammary cells S Goruppi, C Chiaruttini, ME Ruaro, B Varnum, C Schneider Molecular and cellular biology, 2001 | 91 | 2001 |
Nupr1-aurora kinase A pathway provides protection against metabolic stress-mediated autophagic-associated cell death T Hamidi, CE Cano, D Grasso, MN Garcia, MJ Sandi, EL Calvo, ... Clinical Cancer Research 18 (19), 5234-5246, 2012 | 85 | 2012 |
The HumanSerum Deprivation ResponseGene (SDPR) Maps to 2q32–q33 and Codes for a Phosphatidylserine-Binding Protein S Gustincich, P Vatta, S Goruppi, M Wolf, S Saccone, G Della Valle, ... Genomics 57 (1), 120-129, 1999 | 83 | 1999 |
Deficiency of the transcriptional regulator p8 results in increased autophagy and apoptosis, and causes impaired heart function DK Kong, SP Georgescu, C Cano, MJ Aronovitz, JL Iovanna, RD Patten, ... Molecular biology of the cell 21 (8), 1335-1349, 2010 | 70 | 2010 |
Helix-loop-helix protein p8, a transcriptional regulator required for cardiomyocyte hypertrophy and cardiac fibroblast matrix metalloprotease induction S Goruppi, RD Patten, T Force, JM Kyriakis Molecular and cellular biology 27 (3), 993-1006, 2007 | 67 | 2007 |
Mesenchymal stroma: primary determinant and therapeutic target for epithelial cancer S Goruppi, GP Dotto Trends in cell biology 23 (12), 593-602, 2013 | 64 | 2013 |
Androgen receptor functions as transcriptional repressor of cancer-associated fibroblast activation A Clocchiatti, S Ghosh, MG Procopio, L Mazzeo, P Bordignon, P Ostano, ... The Journal of clinical investigation 128 (12), 5531-5548, 2018 | 55 | 2018 |
The pro-hypertrophic basic helix-loop-helix protein p8 is degraded by the ubiquitin/proteasome system in a protein kinase B/Akt-and glycogen synthase kinase-3-dependent manner … S Goruppi, JM Kyriakis Journal of biological chemistry 279 (20), 20950-20958, 2004 | 55 | 2004 |
Decreased metalloprotease 9 induction, cardiac fibrosis, and higher autophagy after pressure overload in mice lacking the transcriptional regulator p8 SP Georgescu, MJ Aronovitz, JL Iovanna, RD Patten, JM Kyriakis, ... American Journal of Physiology-Cell Physiology 301 (5), C1046-C1056, 2011 | 48 | 2011 |
The ULK3 kinase is critical for convergent control of cancer-associated fibroblast activation by CSL and GLI S Goruppi, MG Procopio, S Jo, A Clocchiatti, V Neel, GP Dotto Cell reports 20 (10), 2468-2479, 2017 | 47 | 2017 |
Convergent roles of ATF3 and CSL in chromatin control of cancer-associated fibroblast activation DE Kim, MG Procopio, S Ghosh, SH Jo, S Goruppi, F Magliozzi, ... Journal of Experimental Medicine 214 (8), 2349-2368, 2017 | 36 | 2017 |
NUPR1 works against the metabolic stress-induced autophagy-associated cell death in pancreatic cancer cells T Hamidi, CE Cano, D Grasso, MN Garcia, MJ Sandi, EL Calvo, ... Autophagy 9 (1), 95-97, 2013 | 36 | 2013 |