HSP70 stimulates cytokine production through a CD14-dependant pathway, demonstrating its dual role as a chaperone and cytokine A Asea, SK Kraeft, EA Kurt-Jones, MA Stevenson, LB Chen, RW Finberg, ... Nature medicine 6 (4), 435-442, 2000 | 2132 | 2000 |
Novel signal transduction pathway utilized by extracellular HSP70: role of toll-like receptor (TLR) 2 and TLR4 A Asea, M Rehli, E Kabingu, JA Boch, O Baré, PE Auron, MA Stevenson, ... Journal of Biological Chemistry 277 (17), 15028-15034, 2002 | 2041 | 2002 |
Heat shock proteins in cancer: diagnostic, prognostic, predictive, and treatment implications DR Ciocca, SK Calderwood Cell stress & chaperones 10 (2), 86, 2005 | 1844 | 2005 |
Heat shock proteins in cancer: chaperones of tumorigenesis SK Calderwood, MA Khaleque, DB Sawyer, DR Ciocca Trends in biochemical sciences 31 (3), 164-172, 2006 | 1218 | 2006 |
Sequential phosphorylation by mitogen-activated protein kinase and glycogen synthase kinase 3 represses transcriptional activation by heat shock factor-1 B Chu, F Soncin, BD Price, MA Stevenson, SK Calderwood Journal of Biological Chemistry 271 (48), 30847-30857, 1996 | 498 | 1996 |
Extracellular heat shock proteins in cell signaling SK Calderwood, SS Mambula, PJ Gray Jr, JR Theriault FEBS letters 581 (19), 3689-3694, 2007 | 445 | 2007 |
The shock of aging: molecular chaperones and the heat shock response in longevity and aging–a mini-review SK Calderwood, A Murshid, T Prince Gerontology 55 (5), 550-558, 2009 | 437 | 2009 |
Heat shock protein 70 is secreted from tumor cells by a nonclassical pathway involving lysosomal endosomes SS Mambula, SK Calderwood The Journal of Immunology 177 (11), 7849-7857, 2006 | 433 | 2006 |
Constitutive activation of IκB kinase α and NF-κB in prostate cancer cells is inhibited by ibuprofen ST Palayoor, MY Youmell, SK Calderwood, CN Coleman, BD Price Oncogene 18 (51), 7389-7394, 1999 | 419 | 1999 |
Heat shock proteins promote cancer: it's a protection racket SK Calderwood, J Gong Trends in biochemical sciences 41 (4), 311-323, 2016 | 410 | 2016 |
Tumor-derived heat shock protein 70 peptide complexes are cross-presented by human dendritic cells E Noessner, R Gastpar, V Milani, A Brandl, PJS Hutzler, MC Kuppner, ... The journal of Immunology 169 (10), 5424-5432, 2002 | 372 | 2002 |
The dual immunoregulatory roles of stress proteins AG Pockley, M Muthana, SK Calderwood Trends in biochemical sciences 33 (2), 71-79, 2008 | 340 | 2008 |
Temperature range and selective sensitivity of tumors to hyperthermia: a critical review JA Dickson, SK Calderwood Annals of the New York Academy of Sciences 335 (1), 180-205, 1980 | 335 | 1980 |
X-irradiation, phorbol esters, and H2O2 stimulate mitogen-activated protein kinase activity in NIH-3T3 cells through the formation of reactive oxygen intermediates MA Stevenson, SS Pollock, CN Coleman, SK Calderwood Cancer research 54 (1), 12-15, 1994 | 327 | 1994 |
Heat shock proteins and heat shock factor 1 in carcinogenesis and tumor development: an update DR Ciocca, AP Arrigo, SK Calderwood Archives of toxicology 87, 19-48, 2013 | 322 | 2013 |
Extracellular heat shock proteins in cell signaling and immunity SK Calderwood, SS Mambula, PJ Gray Jr Annals of the New York Academy of Sciences 1113 (1), 28-39, 2007 | 294 | 2007 |
Increases in Sequence Specific DNA Binding by p53 following Treatment with Chemotherapeutic and DNA Damaging Agents RB Tishler, SK Calderwood, CN Coleman, BD Price Cancer Research 53 (10), 2212-2216, 1993 | 289 | 1993 |
Transcriptional repression of the prointerleukin 1β gene by heat shock factor 1 CM Cahill, WR Waterman, Y Xie, PE Auron, SK Calderwood Journal of Biological Chemistry 271 (40), 24874-24879, 1996 | 248 | 1996 |
mTOR is essential for the proteotoxic stress response, HSF1 activation and heat shock protein synthesis SD Chou, T Prince, J Gong, SK Calderwood PloS one 7 (6), e39679, 2012 | 246 | 2012 |
Expression of heat shock proteins and heat shock protein messenger ribonucleic acid in human prostate carcinoma in vitro and in tumors in vivo D Tang, MA Khaleque, EL Jones, JR Theriault, C Li, WH Wong, ... Cell stress & chaperones 10 (1), 46, 2005 | 245 | 2005 |