ROS-dependent activation of the TRAF6-ASK1-p38 pathway is selectively required for TLR4-mediated innate immunity A Matsuzawa, K Saegusa, T Noguchi, C Sadamitsu, H Nishitoh, S Nagai, ... Nature immunology 6 (6), 587-592, 2005 | 761 | 2005 |
ALS-linked mutant SOD1 induces ER stress-and ASK1-dependent motor neuron death by targeting Derlin-1 H Nishitoh, H Kadowaki, A Nagai, T Maruyama, T Yokota, H Fukutomi, ... Genes & development 22 (11), 1451-1464, 2008 | 621 | 2008 |
Thioredoxin and TRAF family proteins regulate reactive oxygen species-dependent activation of ASK1 through reciprocal modulation of the N-terminal homophilic interaction of ASK1 G Fujino, T Noguchi, A Matsuzawa, S Yamauchi, M Saitoh, K Takeda, ... Molecular and cellular biology, 2007 | 341 | 2007 |
Pathophysiological roles of ASK1-MAP kinase signaling pathways H Nagai, T Noguchi, K Takeda, H Ichijo BMB Reports 40 (1), 1-6, 2007 | 333 | 2007 |
Deletion of apoptosis signal-regulating kinase 1 attenuates acetaminophen-induced liver injury by inhibiting c-Jun N-terminal kinase activation H Nakagawa, S Maeda, Y Hikiba, T Ohmae, W Shibata, A Yanai, ... Gastroenterology 135 (4), 1311-1321, 2008 | 281 | 2008 |
Recruitment of tumor necrosis factor receptor-associated factor family proteins to apoptosis signal-regulating kinase 1 signalosome is essential for oxidative stress-induced … T Noguchi, K Takeda, A Matsuzawa, K Saegusa, H Nakano, J Gohda, ... Journal of Biological Chemistry 280 (44), 37033-37040, 2005 | 272 | 2005 |
Apoptosis signal-regulating kinase 1 in stress and immune response K Takeda, T Noguchi, I Naguro, H Ichijo Annu. Rev. Pharmacol. Toxicol. 48 (1), 199-225, 2008 | 271 | 2008 |
Specific recognition of linear polyubiquitin by A20 zinc finger 7 is involved in NF‐κB regulation F Tokunaga, H Nishimasu, R Ishitani, E Goto, T Noguchi, K Mio, K Kamei, ... The EMBO journal 31 (19), 3856-3870, 2012 | 237 | 2012 |
Requirement of reactive oxygen species-dependent activation of ASK1-p38 MAPK pathway for extracellular ATP-induced apoptosis in macrophage T Noguchi, K Ishii, H Fukutomi, I Naguro, A Matsuzawa, K Takeda, H Ichijo Journal of Biological Chemistry 283 (12), 7657-7665, 2008 | 214 | 2008 |
Thioredoxin and protein kinases in redox signaling G Fujino, T Noguchi, K Takeda, H Ichijo Seminars in cancer biology 16 (6), 427-435, 2006 | 198 | 2006 |
Ubiquitin-like sequence in ASK1 plays critical roles in the recognition and stabilization by USP9X and oxidative stress-induced cell death H Nagai, T Noguchi, K Homma, K Katagiri, K Takeda, A Matsuzawa, ... Molecular cell 36 (5), 805-818, 2009 | 182 | 2009 |
ASK1 and ASK2 differentially regulate the counteracting roles of apoptosis and inflammation in tumorigenesis T Iriyama, K Takeda, H Nakamura, Y Morimoto, T Kuroiwa, J Mizukami, ... The EMBO journal 28 (7), 843-853, 2009 | 161 | 2009 |
Mitochondrial phosphoglycerate mutase 5 uses alternate catalytic activity as a protein serine/threonine phosphatase to activate ASK1 K Takeda, Y Komuro, T Hayakawa, H Oguchi, Y Ishida, S Murakami, ... Proceedings of the National Academy of Sciences 106 (30), 12301-12305, 2009 | 158 | 2009 |
Apoptosis signal-regulating kinase (ASK) 2 functions as a mitogen-activated protein kinase kinase kinase in a heteromeric complex with ASK1 K Takeda, R Shimozono, T Noguchi, T Umeda, Y Morimoto, I Naguro, ... Journal of Biological Chemistry 282 (10), 7522-7531, 2007 | 156 | 2007 |
Post-translational modifications of the TAK1-TAB complex Y Hirata, M Takahashi, T Morishita, T Noguchi, A Matsuzawa International journal of molecular sciences 18 (1), 205, 2017 | 147 | 2017 |
The ASK1–MAP kinase pathways in immune and stress responses T Hayakawa, A Matsuzawa, T Noguchi, K Takeda, H Ichijo Microbes and Infection 8 (4), 1098-1107, 2006 | 112 | 2006 |
ASK1-dependent recruitment and activation of macrophages induce hair growth in skin wounds N Osaka, T Takahashi, S Murakami, A Matsuzawa, T Noguchi, T Fujiwara, ... The Journal of cell biology 176 (7), 903-909, 2007 | 102 | 2007 |
ASK3 responds to osmotic stress and regulates blood pressure by suppressing WNK1-SPAK/OSR1 signaling in the kidney I Naguro, T Umeda, Y Kobayashi, J Maruyama, K Hattori, Y Shimizu, ... Nature communications 3 (1), 1285, 2012 | 87 | 2012 |
A TNF- and c-Cbl-dependent FLIPS-degradation pathway and its function in Mycobacterium tuberculosis–induced macrophage apoptosis M Kundu, SK Pathak, K Kumawat, S Basu, G Chatterjee, S Pathak, ... Nature immunology 10 (8), 918-926, 2009 | 82 | 2009 |
TRIM48 promotes ASK1 activation and cell death through ubiquitination-dependent degradation of the ASK1-negative regulator PRMT1 Y Hirata, K Katagiri, K Nagaoka, T Morishita, Y Kudoh, T Hatta, I Naguro, ... Cell reports 21 (9), 2447-2457, 2017 | 63 | 2017 |