| Development and characterization of a microfluidic model of the tumour microenvironment JM Ayuso, M Virumbrales-Muñoz, A Lacueva, PM Lanuza, ... Scientific reports 6 (1), 36086, 2016 | 129 | 2016 |
| Evaluating natural killer cell cytotoxicity against solid tumors using a microfluidic model JM Ayuso, R Truttschel, MM Gong, M Humayun, M Virumbrales-Munoz, ... Oncoimmunology 8 (3), 1553477, 2019 | 125 | 2019 |
| Glioblastoma on a microfluidic chip: Generating pseudopalisades and enhancing aggressiveness through blood vessel obstruction events JM Ayuso, R Monge, A Martínez-González, M Virumbrales-Muñoz, ... Neuro-oncology 19 (4), 503-513, 2017 | 125 | 2017 |
| Microfluidic tumor-on-a-chip model to evaluate the role of tumor environmental stress on NK cell exhaustion JM Ayuso, S Rehman, M Virumbrales-Munoz, PH McMinn, P Geiger, ... Science Advances 7 (8), eabc2331, 2021 | 107 | 2021 |
| A role for microfluidic systems in precision medicine JM Ayuso, M Virumbrales-Muñoz, JM Lang, DJ Beebe Nature communications 13 (1), 3086, 2022 | 97 | 2022 |
| Tumor-on-a-chip: A microfluidic model to study cell response to environmental gradients JM Ayuso, M Virumbrales-Munoz, PH McMinn, S Rehman, I Gomez, ... Lab on a Chip 19 (20), 3461-3471, 2019 | 90 | 2019 |
| Organotypic microfluidic breast cancer model reveals starvation-induced spatial-temporal metabolic adaptations JM Ayuso, A Gillette, K Lugo-Cintrón, S Acevedo-Acevedo, I Gomez, ... EBioMedicine 37, 144-157, 2018 | 81 | 2018 |
| Breast fibroblasts and ECM components modulate breast cancer cell migration through the secretion of MMPs in a 3D microfluidic co-culture model KM Lugo-Cintrón, MM Gong, JM Ayuso, LA Tomko, DJ Beebe, ... Cancers 12 (5), 1173, 2020 | 72 | 2020 |
| Microfluidic lumen-based systems for advancing tubular organ modeling M Virumbrales-Muñoz, JM Ayuso, MM Gong, M Humayun, MK Livingston, ... Chemical Society Reviews 49 (17), 6402-6442, 2020 | 69 | 2020 |
| Human tumor‐lymphatic microfluidic model reveals differential conditioning of lymphatic vessels by breast cancer cells JM Ayuso, MM Gong, MC Skala, PM Harari, DJ Beebe Advanced healthcare materials 9 (3), 1900925, 2020 | 58 | 2020 |
| Activated human primary NK cells efficiently kill colorectal cancer cells in 3D spheroid cultures irrespectively of the level of PD-L1 expression PM Lanuza, A Vigueras, S Olivan, AC Prats, S Costas, G Llamazares, ... Oncoimmunology 7 (4), e1395123, 2018 | 54 | 2018 |
| High-order TRAIL oligomer formation in TRAIL-coated lipid nanoparticles enhances DR5 cross-linking and increases antitumour effect against colon cancer D De Miguel, A Gallego-Lleyda, JM Ayuso, D Pejenaute-Ochoa, V Jarauta, ... Cancer letters 383 (2), 250-260, 2016 | 54 | 2016 |
| Matrix density drives 3D organotypic lymphatic vessel activation in a microfluidic model of the breast tumor microenvironment KM Lugo-Cintrón, JM Ayuso, BR White, PM Harari, SM Ponik, DJ Beebe, ... Lab on a Chip 20 (9), 1586-1600, 2020 | 48 | 2020 |
| Tau protein provides DNA with thermodynamic and structural features which are similar to those found in histone-DNA complex S Camero, MJ Benitez, A Barrantes, JM Ayuso, R Cuadros, J Avila, ... Journal of Alzheimer's Disease 39 (3), 649-660, 2014 | 46 | 2014 |
| TRAIL-coated lipid-nanoparticles overcome resistance to soluble recombinant TRAIL in non-small cell lung cancer cells D De Miguel, A Gallego-Lleyda, JM Ayuso, S Erviti-Ardanaz, R Pazo-Cid, ... Nanotechnology 27 (18), 185101, 2016 | 44 | 2016 |
| Study of the chemotactic response of multicellular spheroids in a microfluidic device JM Ayuso, HA Basheer, R Monge, P Sánchez-Álvarez, M Doblaré, ... PloS one 10 (10), e0139515, 2015 | 42 | 2015 |
| Enabling cell recovery from 3D cell culture microfluidic devices for tumour microenvironment biomarker profiling M Virumbrales-Muñoz, JM Ayuso, A Lacueva, T Randelovic, ... Scientific Reports 9 (1), 6199, 2019 | 38 | 2019 |
| Multiwell capillarity-based microfluidic device for the study of 3D tumour tissue-2D endothelium interactions and drug screening in co-culture models M Virumbrales-Muñoz, JM Ayuso, M Olave, R Monge, D de Miguel, ... Scientific reports 7 (1), 11998, 2017 | 38 | 2017 |
| Agarose Spot as a Comparative Method for in situ Analysis of Simultaneous Chemotactic Responses to Multiple Chemokines M Ahmed, HA Basheer, JM Ayuso, D Ahmet, M Mazzini, R Patel, ... Scientific reports 7 (1), 1075, 2017 | 36 | 2017 |
| Toward improved in vitro models of human cancer JM Ayuso, KY Park, M Virumbrales-Muñoz, DJ Beebe APL bioengineering 5 (1), 2021 | 35 | 2021 |
DAVID J BEEBEUniversity of Wisconsin - MadisonVerified email at wisc.edu