Identification of novel risk loci, causal insights, and heritable risk for Parkinson's disease: a meta-analysis of genome-wide association studies MA Nalls, C Blauwendraat, CL Vallerga, K Heilbron, S Bandres-Ciga, ... The Lancet Neurology 18 (12), 1091-1102, 2019 | 1696 | 2019 |
Tauopathy in Drosophila: neurodegeneration without neurofibrillary tangles CW Wittmann, MF Wszolek, JM Shulman, PM Salvaterra, J Lewis, ... Science 293 (5530), 711-714, 2001 | 1102 | 2001 |
Parkinson's disease: genetics and pathogenesis JM Shulman, PL De Jager, MB Feany Annual Review of Pathology: Mechanisms of Disease 6 (1), 193-222, 2011 | 1042 | 2011 |
Differential recruitment of Dishevelled provides signaling specificity in the planar cell polarity and Wingless signaling pathways JD Axelrod, JR Miller, JM Shulman, RT Moon, N Perrimon Genes & development 12 (16), 2610-2622, 1998 | 823 | 1998 |
Large-scale proteomic analysis of Alzheimer’s disease brain and cerebrospinal fluid reveals early changes in energy metabolism associated with microglia and astrocyte activation ECB Johnson, EB Dammer, DM Duong, L Ping, M Zhou, L Yin, ... Nature medicine 26 (5), 769-780, 2020 | 704 | 2020 |
Prickle mediates feedback amplification to generate asymmetric planar cell polarity signaling DRP Tree, JM Shulman, R Rousset, MP Scott, D Gubb, JD Axelrod Cell 109 (3), 371-381, 2002 | 516 | 2002 |
Functional links between Aβ toxicity, endocytic trafficking, and Alzheimer’s disease risk factors in yeast S Treusch, S Hamamichi, JL Goodman, KES Matlack, CY Chung, V Baru, ... Science 334 (6060), 1241-1245, 2011 | 442 | 2011 |
GWAS of cerebrospinal fluid tau levels identifies risk variants for Alzheimer’s disease C Cruchaga, JSK Kauwe, O Harari, SC Jin, Y Cai, CM Karch, BA Benitez, ... Neuron 78 (2), 256-268, 2013 | 403 | 2013 |
Excessive burden of lysosomal storage disorder gene variants in Parkinson’s disease LA Robak, IE Jansen, J Van Rooij, AG Uitterlinden, R Kraaij, J Jankovic, ... Brain 140 (12), 3191-3203, 2017 | 401 | 2017 |
The Drosophila homolog of C. elegans PAR-1 organizes the oocyte cytoskeleton and directs oskar mRNA localization to the posterior pole JM Shulman, R Benton, D St Johnston Cell 101 (4), 377-388, 2000 | 350 | 2000 |
Parkinson's disease age at onset genome‐wide association study: defining heritability, genetic loci, and α‐synuclein mechanisms C Blauwendraat, K Heilbron, CL Vallerga, S Bandres‐Ciga, R Von Coelln, ... Movement Disorders 34 (6), 866-875, 2019 | 306 | 2019 |
Genetic modifiers of tauopathy in Drosophila JM Shulman, MB Feany Genetics 165 (3), 1233-1242, 2003 | 302 | 2003 |
TOR-mediated cell-cycle activation causes neurodegeneration in a Drosophila tauopathy model V Khurana, Y Lu, ML Steinhilb, S Oldham, JM Shulman, MB Feany Current Biology 16 (3), 230-241, 2006 | 301 | 2006 |
Association of CR1, CLU and PICALM with Alzheimer's disease in a cohort of clinically characterized and neuropathologically verified individuals JJ Corneveaux, AJ Myers, AN Allen, JJ Pruzin, M Ramirez, A Engel, ... Human molecular genetics 19 (16), 3295-3301, 2010 | 299 | 2010 |
Genetic architecture of subcortical brain structures in 38,851 individuals CL Satizabal, HHH Adams, DP Hibar, CC White, MJ Knol, JL Stein, ... Nature genetics 51 (11), 1624-1636, 2019 | 265 | 2019 |
Common variants at 12q14 and 12q24 are associated with hippocampal volume Nature genetics 44 (5), 545-551, 2012 | 261 | 2012 |
Tau activates transposable elements in Alzheimer’s disease C Guo, HH Jeong, YC Hsieh, HU Klein, DA Bennett, PL De Jager, Z Liu, ... Cell reports 23 (10), 2874-2880, 2018 | 260 | 2018 |
A genome-wide association study of depressive symptoms K Hek, A Demirkan, J Lahti, A Terracciano, A Teumer, MC Cornelis, ... Biological psychiatry 73 (7), 667-678, 2013 | 235 | 2013 |
Frizzled signaling and the developmental control of cell polarity JM Shulman, N Perrimon, JD Axelrod Trends in Genetics 14 (11), 452-458, 1998 | 226 | 1998 |
Meta-analysis of the Alzheimer’s disease human brain transcriptome and functional dissection in mouse models YW Wan, R Al-Ouran, CG Mangleburg, TM Perumal, TV Lee, K Allison, ... Cell reports 32 (2), 2020 | 221 | 2020 |