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Not available anywhere: 2
Flotillin-2 deficiency leads to reduced lung metastases in a mouse breast cancer model
T Berger, T Ueda, E Arpaia, IIC Chio, EA Shirdel, I Jurisica, K Hamada, ...
Oncogene 32 (41), 4989-4994, 2013
Mandates: Canadian Institutes of Health Research
TRADD contributes to tumour suppression by regulating ULF-dependent p19Arf ubiquitylation
IIC Chio, M Sasaki, D Ghazarian, J Moreno, S Done, T Ueda, S Inoue, ...
Nature cell biology 14 (6), 625-633, 2012
Mandates: Canadian Institutes of Health Research
Available somewhere: 29
Distinct populations of inflammatory fibroblasts and myofibroblasts in pancreatic cancer
D Öhlund, A Handly-Santana, G Biffi, E Elyada, AS Almeida, ...
Journal of Experimental Medicine 214 (3), 579-596, 2017
Mandates: US Department of Defense, US National Institutes of Health, Swedish Research …
Organoid models of human and mouse ductal pancreatic cancer
SF Boj, CI Hwang, LA Baker, IIC Chio, DD Engle, V Corbo, M Jager, ...
Cell 160 (1), 324-338, 2015
Mandates: US Department of Energy, US National Institutes of Health, Swedish Research …
Transcriptional regulation by Nrf2
C Tonelli, IIC Chio, DA Tuveson
Antioxidants & redox signaling 29 (17), 1727-1745, 2018
Mandates: US Department of Defense, US National Institutes of Health, Dutch Cancer …
Vitamin C selectively kills KRAS and BRAF mutant colorectal cancer cells by targeting GAPDH
J Yun, E Mullarky, C Lu, KN Bosch, A Kavalier, K Rivera, J Roper, IIC Chio, ...
Science 350 (6266), 1391-1396, 2015
Mandates: US National Institutes of Health, Howard Hughes Medical Institute, Damon …
ROS in cancer: the burning question
IIC Chio, DA Tuveson
Trends in molecular medicine 23 (5), 411-429, 2017
Mandates: US National Institutes of Health, V Foundation, USA, Damon Runyon Cancer …
NRF2 promotes tumor maintenance by modulating mRNA translation in pancreatic cancer
IIC Chio, SM Jafarnejad, M Ponz-Sarvise, Y Park, K Rivera, W Palm, ...
Cell 166 (4), 963-976, 2016
Mandates: US Department of Energy, US National Institutes of Health, Canadian …
D-2-hydroxyglutarate produced by mutant IDH1 perturbs collagen maturation and basement membrane function
M Sasaki, CB Knobbe, M Itsumi, AJ Elia, IS Harris, IIC Chio, RA Cairns, ...
Genes & development 26 (18), 2038-2049, 2012
Mandates: US National Institutes of Health, Canadian Institutes of Health Research
Combined deficiency for MAP kinase-interacting kinase 1 and 2 (Mnk1 and Mnk2) delays tumor development
T Ueda, M Sasaki, AJ Elia, IIC Chio, K Hamada, R Fukunaga, TW Mak
Proceedings of the National Academy of Sciences 107 (32), 13984-13990, 2010
Mandates: Canadian Institutes of Health Research
A predictive model for selective targeting of the Warburg effect through GAPDH inhibition with a natural product
MV Liberti, Z Dai, SE Wardell, JA Baccile, X Liu, X Gao, R Baldi, ...
Cell metabolism 26 (4), 648-659. e8, 2017
Mandates: US National Science Foundation, US National Institutes of Health, Canadian …
Mule/Huwe1/Arf-BP1 suppresses Ras-driven tumorigenesis by preventing c-Myc/Miz1-mediated down-regulation of p21 and p15
S Inoue, Z Hao, AJ Elia, D Cescon, L Zhou, J Silvester, B Snow, IS Harris, ...
Genes & development 27 (10), 1101-1114, 2013
Mandates: Canadian Institutes of Health Research, UK Medical Research Council
Beyond tumor necrosis factor receptor: TRADD signaling in toll-like receptors
NJ Chen, IIC Chio, WJ Lin, G Duncan, H Chau, D Katz, HL Huang, ...
Proceedings of the National Academy of Sciences 105 (34), 12429-12434, 2008
Mandates: Canadian Institutes of Health Research
eIF4A supports an oncogenic translation program in pancreatic ductal adenocarcinoma
K Chan, F Robert, C Oertlin, D Kapeller-Libermann, D Avizonis, ...
Nature communications 10 (1), 5151, 2019
Mandates: US National Institutes of Health, Canadian Cancer Society, Canadian …
p53 mutations change phosphatidylinositol acyl chain composition
A Naguib, G Bencze, DD Engle, IIC Chio, T Herzka, K Watrud, S Bencze, ...
Cell reports 10 (1), 8-19, 2015
Mandates: US National Institutes of Health, Damon Runyon Cancer Research Foundation
Bioactivation of napabucasin triggers reactive oxygen species–mediated cancer cell death
FEM Froeling, MM Swamynathan, A Deschênes, IIC Chio, E Brosnan, ...
Clinical Cancer Research 25 (23), 7162-7174, 2019
Mandates: US National Institutes of Health, Pancreatic Cancer Action Network, USA, V …
Identification of resistance pathways specific to malignancy using organoid models of pancreatic cancer
M Ponz-Sarvise, V Corbo, H Tiriac, DD Engle, KK Frese, TE Oni, ...
Clinical Cancer Research 25 (22), 6742-6755, 2019
Mandates: US Department of Energy, US Department of Defense, US National Institutes of …
Metastasis in pancreatic ductal adenocarcinoma: current standing and methodologies
M Ayres Pereira, IIC Chio
Genes 11 (1), 6, 2019
Mandates: US National Institutes of Health, Pancreatic Cancer Action Network, USA
Crucial role for TNF receptor-associated factor 2 (TRAF2) in regulating NFκB2 signaling that contributes to autoimmunity
WJ Lin, YW Su, YC Lu, Z Hao, IIC Chio, NJ Chen, A Brüstle, WY Li, ...
Proceedings of the National Academy of Sciences 108 (45), 18354-18359, 2011
Mandates: Canadian Institutes of Health Research
Methionine oxidation activates pyruvate kinase M2 to promote pancreatic cancer metastasis
D He, H Feng, B Sundberg, J Yang, J Powers, AH Christian, JE Wilkinson, ...
Molecular cell 82 (16), 3045-3060. e11, 2022
Mandates: US National Science Foundation, US National Institutes of Health
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