Hydrogen peroxide inhibits mTOR signaling by activation of AMPKα leading to apoptosis of neuronal cells L Chen, B Xu, L Liu, Y Luo, J Yin, H Zhou, W Chen, T Shen, X Han, ... Laboratory Investigation 90 (5), 762-773, 2010 | 274 | 2010 |
Cadmium induction of reactive oxygen species activates the mTOR pathway, leading to neuronal cell death L Chen, B Xu, L Liu, Y Luo, H Zhou, W Chen, T Shen, X Han, CD Kontos, ... Free Radical Biology and Medicine 50 (5), 624-632, 2011 | 269 | 2011 |
Calcium signaling is involved in cadmium-induced neuronal apoptosis via induction of reactive oxygen species and activation of MAPK/mTOR network B Xu, S Chen, Y Luo, Z Chen, L Liu, H Zhou, W Chen, T Shen, X Han, ... PloS one 6 (4), e19052, 2011 | 226 | 2011 |
Rapamycin inhibits cytoskeleton reorganization and cell motility by suppressing RhoA expression and activity L Liu, Y Luo, L Chen, T Shen, B Xu, W Chen, H Zhou, X Han, S Huang Journal of Biological Chemistry 285 (49), 38362-38373, 2010 | 159 | 2010 |
Ribosomal DNA copy number loss and sequence variation in cancer B Xu, H Li, JM Perry, VP Singh, J Unruh, Z Yu, M Zakari, W McDowell, L Li, ... PLoS genetics 13 (6), e1006771, 2017 | 147 | 2017 |
The antitumor activity of the fungicide ciclopirox H Zhou, T Shen, Y Luo, L Liu, W Chen, B Xu, X Han, J Pang, CA Rivera, ... International Journal of cancer 127 (10), 2467-2477, 2010 | 123 | 2010 |
Cryptotanshinone inhibits cancer cell proliferation by suppressing mammalian target of rapamycin–mediated cyclin D1 expression and Rb phosphorylation W Chen, Y Luo, L Liu, H Zhou, B Xu, X Han, T Shen, Z Liu, Y Lu, S Huang Cancer prevention research 3 (8), 1015-1025, 2010 | 117 | 2010 |
CaMKII is involved in cadmium activation of MAPK and mTOR pathways leading to neuronal cell death S Chen, Y Xu, B Xu, M Guo, Z Zhang, L Liu, H Ma, Z Chen, Y Luo, ... Journal of neurochemistry 119 (5), 1108-1118, 2011 | 114 | 2011 |
Cohesin proteins promote ribosomal RNA production and protein translation in yeast and human cells T Bose, KK Lee, S Lu, B Xu, B Harris, B Slaughter, J Unruh, A Garrett, ... PLoS genetics 8 (6), e1002749, 2012 | 109 | 2012 |
Cadmium exposure induces osteoporosis through cellular senescence, associated with activation of NF-κB pathway and mitochondrial dysfunction H Luo, R Gu, H Ouyang, L Wang, S Shi, Y Ji, B Bao, G Liao, B Xu Environmental Pollution 290, 118043, 2021 | 89 | 2021 |
Stimulation of mTORC1 with L-leucine rescues defects associated with Roberts syndrome B Xu, KK Lee, L Zhang, JL Gerton PLoS genetics 9 (10), e1003857, 2013 | 86 | 2013 |
Epidermal growth factor receptor activation by protein kinase C is necessary for FSH-induced meiotic resumption in porcine cumulus-oocyte complexes X Chen, B Zhou, J Yan, B Xu, P Tai, J Li, S Peng, M Zhang, G Xia Journal of Endocrinology 197 (2), 409-420, 2008 | 85 | 2008 |
Curcumin inhibits protein phosphatases 2A and 5, leading to activation of mitogen-activated protein kinases and death in tumor cells X Han, B Xu, CS Beevers, Y Odaka, L Chen, L Liu, Y Luo, H Zhou, ... Carcinogenesis 33 (4), 868-875, 2012 | 80 | 2012 |
Dihydroartemisinin inhibits the mammalian target of rapamycin-mediated signaling pathways in tumor cells Y Odaka, B Xu, Y Luo, T Shen, C Shang, Y Wu, H Zhou, S Huang Carcinogenesis 35 (1), 192-200, 2014 | 63 | 2014 |
α-Synuclein disrupts stress signaling by inhibiting polo-like kinase Cdc5/Plk2 S Wang, B Xu, LC Liou, Q Ren, S Huang, Y Luo, Z Zhang, SN Witt Proceedings of the National Academy of Sciences 109 (40), 16119-16124, 2012 | 57 | 2012 |
Rapamycin inhibits IGF-1 stimulated cell motility through PP2A pathway L Liu, L Chen, Y Luo, W Chen, H Zhou, B Xu, X Han, T Shen, S Huang PloS one 5 (5), e10578, 2010 | 54 | 2010 |
3′, 5′-cyclic adenosine monophosphate response element binding protein up-regulated cytochrome P450 lanosterol 14α-demethylase expression involved in follicle-stimulating … G Ning, H Ouyang, S Wang, X Chen, B Xu, J Yang, H Zhang, M Zhang, ... Molecular endocrinology 22 (7), 1682-1694, 2008 | 47* | 2008 |
l-leucine partially rescues translational and developmental defects associated with zebrafish models of Cornelia de Lange syndrome B Xu, N Sowa, ME Cardenas, JL Gerton Human molecular genetics 24 (6), 1540-1555, 2015 | 44 | 2015 |
The fungicide ciclopirox inhibits lymphatic endothelial cell tube formation by suppressing VEGFR-3-mediated ERK signaling pathway Y Luo, H Zhou, L Liu, T Shen, W Chen, B Xu, X Han, F Zhang, RS Scott, ... Oncogene 30 (18), 2098-2107, 2011 | 44 | 2011 |
Improved transcription and translation with L-leucine stimulation of mTORC1 in Roberts syndrome B Xu, M Gogol, K Gaudenz, JL Gerton BMC genomics 17, 1-18, 2016 | 42 | 2016 |