| Small-molecule inhibitors of HIV-1 entry block receptor-induced conformational changes in the viral envelope glycoproteins Z Si, N Madani, JM Cox, JJ Chruma, JC Klein, A Schön, N Phan, L Wang, ... Proceedings of the National Academy of Sciences 101 (14), 5036-5041, 2004 | 330 | 2004 |
| Inhibitors of SARS-CoV-2 entry: current and future opportunities S Xiu, A Dick, H Ju, S Mirzaie, F Abdi, S Cocklin, P Zhan, X Liu Journal of medicinal chemistry 63 (21), 12256-12274, 2020 | 218 | 2020 |
| Inhibition of homologous recombination in human cells by targeting RAD51 recombinase F Huang, OM Mazina, IJ Zentner, S Cocklin, AV Mazin Journal of medicinal chemistry 55 (7), 3011-3020, 2012 | 146 | 2012 |
| The structure of the negative transcriptional regulator NmrA reveals a structural superfamily which includes the short-chain dehydrogenase/reductases DK Stammers, J Ren, K Leslie, CE Nichols, HK Lamb, S Cocklin, A Dodds, ... The EMBO journal 20 (23), 6619-6626, 2001 | 136 | 2001 |
| Targeting BRCA1-and BRCA2-deficient cells with RAD52 small molecule inhibitors F Huang, N Goyal, K Sullivan, K Hanamshet, M Patel, OM Mazina, ... Nucleic acids research 44 (9), 4189-4199, 2016 | 117 | 2016 |
| High-resolution crystal structure reveals molecular details of target recognition by bacitracin NJ Economou, S Cocklin, PJ Loll Proceedings of the National Academy of Sciences 110 (35), 14207-14212, 2013 | 101 | 2013 |
| Enhanced EGFR inhibition and distinct epitope recognition by EGFR antagonistic mAbs C225 and 425 V Kamat, JM Donaldson, C Kari, MRD Quadros, PI Lelkes, I Chaiken, ... Cancer biology & therapy 7 (5), 726-733, 2008 | 100 | 2008 |
| Mode of action for linear peptide inhibitors of HIV-1 gp120 interactions AC Biorn, S Cocklin, N Madani, Z Si, T Ivanovic, J Samanen, DI Van Ryk, ... Biochemistry 43 (7), 1928-1938, 2004 | 90 | 2004 |
| Inhibiting early-stage events in HIV-1 replication by small-molecule targeting of the HIV-1 capsid S Kortagere, N Madani, MK Mankowski, A Schön, I Zentner, ... Journal of virology 86 (16), 8472-8481, 2012 | 88 | 2012 |
| Design, synthesis and structure-activity relationships of 4-phenyl-1H-1, 2, 3-triazole phenylalanine derivatives as novel HIV-1 capsid inhibitors with promising antiviral … L Sun, T Huang, A Dick, ME Meuser, WA Zalloum, CH Chen, X Ding, ... European journal of medicinal chemistry 190, 112085, 2020 | 86 | 2020 |
| Structure, function, and interactions of the HIV-1 capsid protein E Rossi, ME Meuser, CJ Cunanan, S Cocklin Life 11 (2), 100, 2021 | 73 | 2021 |
| The V1-V3 region of a brain-derived HIV-1 envelope glycoprotein determines macrophage tropism, low CD4 dependence, increased fusogenicity and altered sensitivity to entry … F Rossi, B Querido, M Nimmagadda, S Cocklin, S Navas-Martín, ... Retrovirology 5, 1-22, 2008 | 70 | 2008 |
| Small Molecule Modulators of HIV-1 Capsid Stability and Methods Thereof S Cocklin, S Kortagere, AB Smith III US Patent App. 13/643,392, 2013 | 69 | 2013 |
| Discovery of phenylalanine derivatives as potent HIV-1 capsid inhibitors from click chemistry-based compound library G Wu, WA Zalloum, ME Meuser, L Jing, D Kang, CH Chen, Y Tian, ... European journal of medicinal chemistry 158, 478-492, 2018 | 62 | 2018 |
| Broad-spectrum anti-human immunodeficiency virus (HIV) potential of a peptide HIV type 1 entry inhibitor S Cocklin, H Gopi, B Querido, M Nimmagadda, S Kuriakose, C Cicala, ... Journal of virology 81 (7), 3645-3648, 2007 | 62 | 2007 |
| PDZ domains facilitate binding of high temperature requirement protease A (HtrA) and tail-specific protease (Tsp) to heterologous substrates through recognition of the small … A Spiers, HK Lamb, S Cocklin, KA Wheeler, J Budworth, AL Dodds, ... Journal of Biological Chemistry 277 (42), 39443-39449, 2002 | 62 | 2002 |
| Introducing metallocene into a triazole peptide conjugate reduces its off‐rate and enhances its affinity and antiviral potency for HIV‐1 gp120 H Gopi, S Cocklin, V Pirrone, K McFadden, F Tuzer, I Zentner, S Ajith, ... Journal of Molecular Recognition: An Interdisciplinary Journal 22 (2), 169-174, 2009 | 60 | 2009 |
| Bioisosteric replacement as a tool in anti-HIV drug design A Dick, S Cocklin Pharmaceuticals 13 (3), 36, 2020 | 58 | 2020 |
| Structural determinants for affinity enhancement of a dual antagonist peptide entry inhibitor of human immunodeficiency virus type-1 H Gopi, M Umashankara, V Pirrone, J LaLonde, N Madani, F Tuzer, ... Journal of medicinal chemistry 51 (9), 2638-2647, 2008 | 58 | 2008 |
| Modulation of the ligand binding properties of the transcription repressor NmrA by GATA‐containing DNA and site‐directed mutagenesis HK Lamb, J Ren, A Park, C Johnson, K Leslie, S Cocklin, P Thompson, ... Protein science 13 (12), 3127-3138, 2004 | 58 | 2004 |