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Nathaniel W. Mabe
Nathaniel W. Mabe
Verified email at purdue.edu
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Cited by
Cited by
Year
Epigenetic silencing of tumor suppressor Par-4 promotes chemoresistance in recurrent breast cancer
NW Mabe, DB Fox, R Lupo, AE Decker, SN Phelps, JW Thompson, ...
The Journal of clinical investigation 128 (10), 4413-4428, 2018
512018
Transition to a mesenchymal state in neuroblastoma confers resistance to anti-GD2 antibody via reduced expression of ST8SIA1
NW Mabe, M Huang, GN Dalton, G Alexe, DA Schaefer, AC Geraghty, ...
Nature cancer 3 (8), 976-993, 2022
492022
RIPK3 upregulation confers robust proliferation and collateral cystine-dependence on breast cancer recurrence
CC Lin, NW Mabe, YT Lin, WH Yang, X Tang, L Hong, T Sun, J Force, ...
Cell Death & Differentiation 27 (7), 2234-2247, 2020
422020
Adaptation and selection shape clonal evolution of tumors during residual disease and recurrence
A Walens, J Lin, JS Damrauer, B McKinney, R Lupo, R Newcomb, DB Fox, ...
Nature communications 11 (1), 5017, 2020
372020
G9a promotes breast cancer recurrence through repression of a pro-inflammatory program
NW Mabe, NMG Garcia, SE Wolery, R Newcomb, RC Meingasner, ...
Cell reports 33 (5), 2020
282020
The ETS transcription factor ETV6 constrains the transcriptional activity of EWS–FLI to promote Ewing sarcoma
DY Lu, JM Ellegast, KN Ross, CF Malone, S Lin, NW Mabe, NV Dharia, ...
Nature Cell Biology 25 (2), 285-297, 2023
212023
Regulator of G protein signaling 6 protects the heart from ischemic injury
BR Rorabaugh, B Chakravarti, NW Mabe, SL Seeley, AD Bui, J Yang, ...
Journal of Pharmacology and Experimental Therapeutics 360 (3), 409-416, 2017
212017
i2-mediated protection from ischaemic injury is modulated by endogenous RGS proteins in the mouse heart
RE Waterson, CG Thompson, NW Mabe, K Kaur, JN Talbot, RR Neubig, ...
Cardiovascular research 91 (1), 45-52, 2011
212011
Foxo-dependent Par-4 upregulation prevents long-term survival of residual cells following PI3K–Akt inhibition
JS Damrauer, SN Phelps, K Amuchastegui, R Lupo, NW Mabe, A Walens, ...
Molecular Cancer Research 16 (4), 599-609, 2018
192018
VRK1 as a synthetic lethal target in VRK2 promoter–methylated cancers of the nervous system
J So, NW Mabe, B Englinger, KH Chow, SM Moyer, S Yerrum, MC Trissal, ...
JCI insight 7 (19), 2022
152022
Myocardial fibrosis, inflammation, and altered cardiac gene expression profiles in rats exposed to a predator-based model of posttraumatic stress disorder
BR Rorabaugh, NW Mabe, SL Seeley, TS Stoops, KE Mucher, CP Ney, ...
Stress 23 (2), 125-135, 2020
142020
Pharmacological targeting of the cancer epigenome
NW Mabe, JA Perry, CF Malone, K Stegmaier
Nature Cancer 5 (6), 844-865, 2024
32024
VRK1 is required in VRK2-methylated cancers of the nervous system
J So, NW Mabe, B Englinger, SM Moyer, MC Trissal, JG Marques, J Kwon, ...
bioRxiv, 2021.12. 28.474386, 2021
22021
The KAT module of the SAGA complex maintains the oncogenic gene expression program in MYCN-amplified neuroblastoma
CF Malone, NW Mabe, AB Forman, G Alexe, KL Engel, YJC Chen, ...
Science Advances 10 (22), eadm9449, 2024
12024
Regulator of G protein signaling protein 6 (RGS6) protects the heart from ischemic injury
B Rorabaugh, N Mabe, S Seeley, A Bui, J Yang, R Neubig, R Fisher
The FASEB Journal 29, 1026.8, 2015
12015
Abstract A062 Therapeutic targeting of the SAGA KAT module impairs MYCN-amplified neuroblastoma growth through reduction of the MYCN oncogenic gene expression program
NW Mabe, CF Malone, AB Forman, G Alexe, KL Engel, YJC Chen, ...
Cancer Research 84 (17_Supplement), A062-A062, 2024
2024
Lineage-dependence of the neuroblastoma surfaceome defines tumor cell state-dependent and independent immunotherapeutic targets
NM Kendsersky, M Odrobina, NW Mabe, A Farrel, L Grossmann, M Tsang, ...
bioRxiv, 2024.06. 27.600865, 2024
2024
244 Targeting gangliosides in pediatric cancer
GN Dalton, WJ Kim, NW Mabe, M Huang, MC Rotiroti, AM Tousley, ...
Journal for ImmunoTherapy of Cancer 11 (Suppl 1), 2023
2023
Abstract PR003: Lineage plasticity dictates responsiveness to anti-GD2 therapy in neuroblastoma
NW Mabe, M Huang, DA Schaefer, GN Dalton, G Digiovanni, G Alexe, ...
Cancer Research 82 (23_Supplement_2), PR003-PR003, 2022
2022
Synthetic lethality of VRK1 in VRK2-methylated cancers
J So, N Mabe, B Englinger, J Kwon, B Shim, M Filbin, K Stegmaier, ...
Cancer Research 82 (12_Supplement), 2147-2147, 2022
2022
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