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Jeffrey Macdonald
Jeffrey Macdonald
Professor of Biomedical Engineering, University of North Carolina
Verified email at med.unc.edu - Homepage
Title
Cited by
Cited by
Year
Combination of ERK and autophagy inhibition as a treatment approach for pancreatic cancer
KL Bryant, CA Stalnecker, D Zeitouni, JE Klomp, S Peng, AP Tikunov, ...
Nature medicine 25 (4), 628-640, 2019
5952019
Citrate as an in vivo marker to discriminate prostate cancer from benign prostatic hyperplasia and normal prostate peripheral zone: detection via localized proton spectroscopy
J Kurhanewicz, DB Vigneron, SJ Nelson, H Hricak, JM MacDonald, ...
Urology 45 (3), 459-466, 1995
2961995
In vivo Hypoxia and a Fungal Alcohol Dehydrogenase Influence the Pathogenesis of Invasive Pulmonary Aspergillosis
N Grahl, S Puttikamonkul, JM Macdonald, MP Gamcsik, LY Ngo, TM Hohl, ...
PLoS pathogens 7 (7), e1002145, 2011
2422011
Chemosensitivity of IDH1-mutated gliomas due to an impairment in PARP1-mediated DNA repair
Y Lu, J Kwintkiewicz, Y Liu, K Tech, LN Frady, YT Su, W Bautista, SI Moon, ...
Cancer research 77 (7), 1709-1718, 2017
2112017
Multi-compound polarization by DNP allows simultaneous assessment of multiple enzymatic activities in vivo
DM Wilson, KR Keshari, PEZ Larson, AP Chen, S Hu, M Van Criekinge, ...
Journal of magnetic resonance 205 (1), 141-147, 2010
2072010
Use of pharmaco‐metabonomics for early prediction of acetaminophen‐induced hepatotoxicity in humans
JH Winnike, Z Li, FA Wright, JM Macdonald, TM O'connell, PB Watkins
Clinical Pharmacology & Therapeutics 88 (1), 45-51, 2010
1802010
Differential dynamical effects of macromolecular crowding on an intrinsically disordered protein and a globular protein: implications for in-cell NMR spectroscopy
C Li, LM Charlton, A Lakkavaram, C Seagle, G Wang, GB Young, ...
Journal of the American Chemical Society 130 (20), 6310-6311, 2008
1702008
Citrate alterations in primary and metastatic human prostatic adenocarcinomas: 1H magnetic resonance spectroscopy and biochemical study
J Kurhanewicz, R Dahiya, JM Macdonald, LH Chang, TL James, ...
Magnetic resonance in medicine 29 (2), 149-157, 1993
1491993
Hyperpolarized [2-13C]-Fructose: A Hemiketal DNP Substrate for In Vivo Metabolic Imaging
KR Keshari, DM Wilson, AP Chen, R Bok, PEZ Larson, S Hu, ...
Journal of the American Chemical Society 131 (48), 17591-17596, 2009
1332009
Ribosomal protein–Mdm2–p53 pathway coordinates nutrient stress with lipid metabolism by regulating MCD and promoting fatty acid oxidation
Y Liu, Y He, A Jin, AP Tikunov, L Zhou, LA Tollini, P Leslie, TH Kim, LO Li, ...
Proceedings of the National Academy of Sciences 111 (23), E2414-E2422, 2014
1282014
Acetaminophen dosing of humans results in blood transcriptome and metabolome changes consistent with impaired oxidative phosphorylation
RD Fannin, M Russo, TM O'Connell, K Gerrish, JH Winnike, J Macdonald, ...
Hepatology 51 (1), 227-236, 2010
1142010
Hexokinase-2-mediated aerobic glycolysis is integral to cerebellar neurogenesis and pathogenesis of medulloblastoma
TR Gershon, AJ Crowther, A Tikunov, I Garcia, R Annis, H Yuan, CR Miller, ...
Cancer & metabolism 1, 1-17, 2013
1082013
A sterol-binding protein integrates endosomal lipid metabolism with TOR signaling and nitrogen sensing
CJ Mousley, P Yuan, NA Gaur, KD Trettin, AH Nile, SJ Deminoff, ...
Cell 148 (4), 702-715, 2012
962012
Closure of VDAC causes oxidative stress and accelerates the Ca2+-induced mitochondrial permeability transition in rat liver mitochondria
A Tikunov, CB Johnson, P Pediaditakis, N Markevich, JM Macdonald, ...
Archives of biochemistry and biophysics 495 (2), 174-181, 2010
952010
Hyperpolarized 13C spectroscopy and an NMR‐compatible bioreactor system for the investigation of real‐time cellular metabolism
KR Keshari, J Kurhanewicz, RE Jeffries, DM Wilson, BJ Dewar, ...
Magnetic Resonance in Medicine: An Official Journal of the International …, 2010
922010
Bioreactor design and process for engineering tissue from cells
JM MacDonald, SP Wolfe
US Patent 6,979,308, 2005
922005
Iron control of erythroid development by a novel aconitase-associated regulatory pathway
GC Bullock, LL Delehanty, AL Talbot, SL Gonias, WH Tong, TA Rouault, ...
Blood, The Journal of the American Society of Hematology 116 (1), 97-108, 2010
892010
p53 coordinates DNA repair with nucleotide synthesis by suppressing PFKFB3 expression and promoting the pentose phosphate pathway
DA Franklin, Y He, PL Leslie, AP Tikunov, N Fenger, JM Macdonald, ...
Scientific reports 6 (1), 38067, 2016
862016
Metabolomic Investigations of American Oysters Using 1H-NMR Spectroscopy
AP Tikunov, CB Johnson, H Lee, MK Stoskopf, JM Macdonald
Marine drugs 8 (10), 2578-2596, 2010
852010
1H NMR-Based Metabolomic Analysis of Liver, Serum, and Brain Following Ethanol Administration in Rats
PC Nicholas, D Kim, FT Crews, JM Macdonald
Chemical Research in Toxicology 21 (2), 408-420, 2008
752008
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