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Genome-wide polygenic scores for common diseases identify individuals with risk equivalent to monogenic mutations AV Khera, M Chaffin, KG Aragam, ME Haas, C Roselli, SH Choi, ... Nature genetics 50 (9), 1219-1224, 2018 | 2638 | 2018 |
Clonal hematopoiesis and risk of atherosclerotic cardiovascular disease S Jaiswal, P Natarajan, AJ Silver, CJ Gibson, AG Bick, E Shvartz, ... New England Journal of Medicine 377 (2), 111-121, 2017 | 2172 | 2017 |
Sequencing of 53,831 diverse genomes from the NHLBI TOPMed Program D Taliun, DN Harris, MD Kessler, J Carlson, ZA Szpiech, R Torres, ... Nature 590 (7845), 290-299, 2021 | 1472 | 2021 |
Genetic risk, adherence to a healthy lifestyle, and coronary disease AV Khera, CA Emdin, I Drake, P Natarajan, AG Bick, NR Cook, ... New England Journal of Medicine 375 (24), 2349-2358, 2016 | 1380 | 2016 |
Diagnostic yield and clinical utility of sequencing familial hypercholesterolemia genes in patients with severe hypercholesterolemia AV Khera, HH Won, GM Peloso, KS Lawson, TM Bartz, X Deng, ... Journal of the American College of Cardiology 67 (22), 2578-2589, 2016 | 941 | 2016 |
Genetics of blood lipids among~ 300,000 multi-ethnic participants of the Million Veteran Program D Klarin, SM Damrauer, K Cho, YV Sun, TM Teslovich, J Honerlaw, ... Nature genetics 50 (11), 1514-1523, 2018 | 578 | 2018 |
Lipoprotein (a) in atherosclerotic cardiovascular disease and aortic stenosis: a European Atherosclerosis Society consensus statement F Kronenberg, S Mora, ESG Stroes, BA Ference, BJ Arsenault, L Berglund, ... European heart journal 43 (39), 3925-3946, 2022 | 550 | 2022 |
Polygenic risk score identifies subgroup with higher burden of atherosclerosis and greater relative benefit from statin therapy in the primary prevention setting P Natarajan, R Young, NO Stitziel, S Padmanabhan, U Baber, R Mehran, ... Circulation 135 (22), 2091-2101, 2017 | 527 | 2017 |
The power of genetic diversity in genome-wide association studies of lipids SE Graham, SL Clarke, KHH Wu, S Kanoni, GJM Zajac, S Ramdas, ... Nature 600 (7890), 675-679, 2021 | 494 | 2021 |
Inherited causes of clonal haematopoiesis in 97,691 whole genomes AG Bick, JS Weinstock, SK Nandakumar, CP Fulco, EL Bao, SM Zekavat, ... Nature 586 (7831), 763-768, 2020 | 486 | 2020 |
Inactivating Mutations in NPC1L1 and Protection from Coronary Heart Disease Myocardial Infarction Genetics Consortium Investigators New England Journal of Medicine 371 (22), 2072-2082, 2014 | 471 | 2014 |
ANGPTL3 deficiency and protection against coronary artery disease NO Stitziel, AV Khera, X Wang, AJ Bierhals, AC Vourakis, AE Sperry, ... Journal of the American College of Cardiology 69 (16), 2054-2063, 2017 | 452 | 2017 |
Genetic association of waist-to-hip ratio with cardiometabolic traits, type 2 diabetes, and coronary heart disease CA Emdin, AV Khera, P Natarajan, D Klarin, SM Zekavat, AJ Hsiao, ... Jama 317 (6), 626-634, 2017 | 410 | 2017 |
Association of premature natural and surgical menopause with incident cardiovascular disease MC Honigberg, SM Zekavat, K Aragam, P Finneran, D Klarin, DL Bhatt, ... Jama 322 (24), 2411-2421, 2019 | 339 | 2019 |
Genetic interleukin 6 signaling deficiency attenuates cardiovascular risk in clonal hematopoiesis AG Bick, JP Pirruccello, GK Griffin, N Gupta, S Gabriel, D Saleheen, ... Circulation 141 (2), 124-131, 2020 | 327 | 2020 |
High-density lipoprotein and coronary heart disease: current and future therapies P Natarajan, KK Ray, CP Cannon Journal of the American College of Cardiology 55 (13), 1283-1299, 2010 | 323 | 2010 |
Human knockouts and phenotypic analysis in a cohort with a high rate of consanguinity D Saleheen, P Natarajan, IM Armean, W Zhao, A Rasheed, SA Khetarpal, ... Nature 544 (7649), 235-239, 2017 | 321 | 2017 |
A statistical framework for cross-tissue transcriptome-wide association analysis Y Hu, M Li, Q Lu, H Weng, J Wang, SM Zekavat, Z Yu, B Li, J Gu, ... Nature genetics 51 (3), 568-576, 2019 | 300 | 2019 |
Whole-genome sequencing to characterize monogenic and polygenic contributions in patients hospitalized with early-onset myocardial infarction AV Khera, M Chaffin, SM Zekavat, RL Collins, C Roselli, P Natarajan, ... Circulation 139 (13), 1593-1602, 2019 | 256 | 2019 |