The transcriptional coactivator PGC-1α mediates exercise-induced angiogenesis in skeletal muscle J Chinsomboon, J Ruas, RK Gupta, R Thom, J Shoag, GC Rowe, ... Proceedings of the national academy of sciences 106 (50), 21401-21406, 2009 | 486 | 2009 |
cGMP-dependent protein kinase phosphorylates and inactivates RhoA N Sawada, H Itoh, J Yamashita, K Doi, M Inoue, K Masatsugu, ... Biochemical and biophysical research communications 280 (3), 798-805, 2001 | 286 | 2001 |
Inhibition of rho-associated kinase results in suppression of neointimal formation of balloon-injured arteries N Sawada, H Itoh, K Ueyama, J Yamashita, K Doi, TH Chun, M Inoue, ... Circulation 101 (17), 2030-2033, 2000 | 268 | 2000 |
Oxidized LDL regulates vascular endothelial growth factor expression in human macrophages and endothelial cells through activation of peroxisome proliferator–activated receptor-γ M Inoue, H Itoh, T Tanaka, TH Chun, K Doi, Y Fukunaga, N Sawada, ... Arteriosclerosis, thrombosis, and vascular biology 21 (4), 560-566, 2001 | 220 | 2001 |
Significance and therapeutic potential of the natriuretic peptides/cGMP/cGMP-dependent protein kinase pathway in vascular regeneration K Yamahara, H Itoh, TH Chun, Y Ogawa, J Yamashita, N Sawada, ... Proceedings of the National Academy of Sciences 100 (6), 3404-3409, 2003 | 205 | 2003 |
ROCK1 mediates leukocyte recruitment and neointima formation following vascular injury K Noma, Y Rikitake, N Oyama, G Yan, P Alcaide, PY Liu, H Wang, D Ahl, ... The Journal of clinical investigation 118 (5), 1632-1644, 2008 | 189 | 2008 |
Obesity increases vascular senescence and susceptibility to ischemic injury through chronic activation of Akt and mTOR CY Wang, HH Kim, Y Hiroi, N Sawada, S Salomone, LE Benjamin, ... Science signaling 2 (62), ra11-ra11, 2009 | 186 | 2009 |
Down regulation of peroxisome proliferator-activated receptorγ expression by inflammatory cytokines and its reversal by thiazolidinediones T Tanaka, H Itoh, K Doi, Y Fukunaga, K Hosoda, M Shintani, J Yamashita, ... Diabetologia 42, 702-710, 1999 | 176 | 1999 |
Pathway for differentiation of human embryonic stem cells to vascular cell components and their potential for vascular regeneration M Sone, H Itoh, K Yamahara, JK Yamashita, T Yurugi-Kobayashi, ... Arteriosclerosis, thrombosis, and vascular biology 27 (10), 2127-2134, 2007 | 173 | 2007 |
Endothelial PGC-1α mediates vascular dysfunction in diabetes N Sawada, A Jiang, F Takizawa, A Safdar, A Manika, Y Tesmenitsky, ... Cell metabolism 19 (2), 246-258, 2014 | 170 | 2014 |
Thiazolidinediones, peroxisome proliferator-activated receptor γ agonists, regulate endothelial cell growth and secretion of vasoactive peptides Y Fukunaga, H Itoh, K Doi, T Tanaka, J Yamashita, TH Chun, M Inoue, ... Atherosclerosis 158 (1), 113-119, 2001 | 158 | 2001 |
Oxidative stress augments secretion of endothelium-derived relaxing peptides, C-type natriuretic peptide and adrenomedullin TH Chun, H Itoh, T Saito, K Yamahara, K Doi, Y Mori, Y Ogawa, ... Journal of hypertension 18 (5), 575-580, 2000 | 118 | 2000 |
Accelerated reendothelialization with suppressed thrombogenic property and neointimal hyperplasia of rabbit jugular vein grafts by adenovirus-mediated gene transfer of C-type … N Ohno, H Itoh, T Ikeda, K Ueyama, K Yamahara, K Doi, J Yamashita, ... Circulation 105 (14), 1623-1626, 2002 | 114 | 2002 |
C-type natriuretic peptide induces redifferentiation of vascular smooth muscle cells with accelerated reendothelialization K Doi, T Ikeda, H Itoh, K Ueyama, K Hosoda, Y Ogawa, J Yamashita, ... Arteriosclerosis, thrombosis, and vascular biology 21 (6), 930-936, 2001 | 114 | 2001 |
Regulation of endothelial nitric oxide synthase and postnatal angiogenesis by Rac1 N Sawada, S Salomone, HH Kim, DJ Kwiatkowski, JK Liao Circulation research 103 (4), 360-368, 2008 | 107 | 2008 |
Different differentiation kinetics of vascular progenitor cells in primate and mouse embryonic stem cells M Sone, H Itoh, J Yamashita, T Yurugi-Kobayashi, Y Suzuki, Y Kondo, ... Circulation 107 (16), 2085-2088, 2003 | 107 | 2003 |
Adrenomedullin promotes proliferation and migration of cultured endothelial cells K Miyashita, H Itoh, N Sawada, Y Fukunaga, M Sone, K Yamahara, ... Hypertension Research 26 (Suppl), S93-S98, 2003 | 105 | 2003 |
Role of transient receptor potential vanilloid 2 in LPS-induced cytokine production in macrophages K Yamashiro, T Sasano, K Tojo, I Namekata, J Kurokawa, N Sawada, ... Biochemical and biophysical research communications 398 (2), 284-289, 2010 | 101 | 2010 |
Physiological concentration of atrial natriuretic peptide induces endothelial regeneration in vitro H Kook, H Itoh, BS Choi, N Sawada, K Doi, TJ Hwang, KK Kim, H Arai, ... American Journal of Physiology-Heart and Circulatory Physiology 284 (4 …, 2003 | 101 | 2003 |
Adrenomedullin provokes endothelial Akt activation and promotes vascular regeneration both in vitro and in vivo K Miyashita, H Itoh, N Sawada, Y Fukunaga, M Sone, K Yamahara, ... FEBS letters 544 (1-3), 86-92, 2003 | 98 | 2003 |