The transcriptional landscape of the mammalian genome P Carninci, T Kasukawa, S Katayama, J Gough, MC Frith, N Maeda, ... science 309 (5740), 1559-1563, 2005 | 4094 | 2005 |
Position-independent, high-level expression of the human β-globin gene in transgenic mice F Grosveld, GB van Assendelft, DR Greaves, G Kollias Cell 51 (6), 975-985, 1987 | 2477 | 1987 |
Transgenic mice expressing human tumour necrosis factor: a predictive genetic model of arthritis. J Keffer, L Probert, H Cazlaris, S Georgopoulos, E Kaslaris, D Kioussis, ... The EMBO journal 10 (13), 4025-4031, 1991 | 2024 | 1991 |
Onset and progression in inherited ALS determined by motor neurons and microglia S Boillée, K Yamanaka, CS Lobsiger, NG Copeland, NA Jenkins, ... Science 312 (5778), 1389-1392, 2006 | 1921 | 2006 |
The transmembrane form of tumor necrosis factor is the prime activating ligand of the 80 kDa tumor necrosis factor receptor M Grell, E Douni, H Wajant, M Löhden, M Clauss, B Maxeiner, ... Cell 83 (5), 793-802, 1995 | 1767 | 1995 |
Impaired on/off regulation of TNF biosynthesis in mice lacking TNF AU-rich elements: implications for joint and gut-associated immunopathologies D Kontoyiannis, M Pasparakis, TT Pizarro, F Cominelli, G Kollias Immunity 10 (3), 387-398, 1999 | 1686 | 1999 |
Immune and inflammatory responses in TNF alpha-deficient mice: a critical requirement for TNF alpha in the formation of primary B cell follicles, follicular dendritic cell … M Pasparakis, L Alexopoulou, V Episkopou, G Kollias The Journal of experimental medicine 184 (4), 1397-1411, 1996 | 1446 | 1996 |
CXCR4-activated astrocyte glutamate release via TNFα: amplification by microglia triggers neurotoxicity P Bezzi, M Domercq, L Brambilla, R Galli, D Schols, E De Clercq, ... Nature neuroscience 4 (7), 702-710, 2001 | 1266 | 2001 |
Mice deficient in tumor necrosis factor-α are resistant to skin carcinogenesis RJ Moore, DM Owens, G Stamp, C Arnott, F Burke, N East, H Holdsworth, ... Nature medicine 5 (7), 828-831, 1999 | 1057 | 1999 |
TNF-α induction by LPS is regulated posttranscriptionally via a Tpl2/ERK-dependent pathway CD Dumitru, JD Ceci, C Tsatsanis, D Kontoyiannis, K Stamatakis, JH Lin, ... Cell 103 (7), 1071-1083, 2000 | 1037 | 2000 |
Interleukin 6 is required for the development of collagen-induced arthritis T Alonzi, E Fattori, D Lazzaro, P Costa, L Probert, G Kollias, ... The Journal of experimental medicine 187 (4), 461, 1998 | 816 | 1998 |
Osteoclasts are essential for TNF-α–mediated joint destruction K Redlich, S Hayer, R Ricci, JP David, M Tohidast-Akrad, G Kollias, ... The Journal of clinical investigation 110 (10), 1419-1427, 2002 | 754 | 2002 |
Transgenic mice expressing the human heat shock protein 70 have improved post-ischemic myocardial recovery. JC Plumier, BM Ross, RW Currie, CE Angelidis, H Kazlaris, G Kollias, ... The Journal of clinical investigation 95 (4), 1854-1860, 1995 | 712 | 1995 |
MK2 targets AU-rich elements and regulates biosynthesis of tumor necrosis factor and interleukin-6 independently at different post-transcriptional levels A Neininger, D Kontoyiannis, A Kotlyarov, R Winzen, R Eckert, HD Volk, ... Journal of Biological Chemistry 277 (5), 3065-3068, 2002 | 513 | 2002 |
Spontaneous inflammatory demyelinating disease in transgenic mice showing central nervous system-specific expression of tumor necrosis factor alpha. L Probert, K Akassoglou, M Pasparakis, G Kontogeorgos, G Kollias Proceedings of the National Academy of Sciences 92 (24), 11294-11298, 1995 | 504 | 1995 |
Predominant pathogenic role of tumor necrosis factor in experimental colitis in mice MF Neurath, I Fuss, M Pasparakis, L Alexopoulou, S Haralambous, ... European journal of immunology 27 (7), 1743-1750, 1997 | 503 | 1997 |
Endothelial cell-specific NF-κB inhibition protects mice from atherosclerosis R Gareus, E Kotsaki, S Xanthoulea, I van der Made, MJJ Gijbels, ... Cell metabolism 8 (5), 372-383, 2008 | 489 | 2008 |
Mast cells control neutrophil recruitment during T cell–mediated delayed-type hypersensitivity reactions through tumor necrosis factor and macrophage inflammatory protein 2 T Biedermann, M Kneilling, R Mailhammer, K Maier, CA Sander, G Kollias, ... The Journal of experimental medicine 192 (10), 1441, 2000 | 483 | 2000 |
Proof of concept: enthesitis and new bone formation in spondyloarthritis are driven by mechanical strain and stromal cells P Jacques, S Lambrecht, E Verheugen, E Pauwels, G Kollias, M Armaka, ... Annals of the rheumatic diseases 73 (2), 437-445, 2014 | 471 | 2014 |
Uncoupling the proinflammatory from the immunosuppressive properties of tumor necrosis factor (TNF) at the p55 TNF receptor level: implications for pathogenesis and therapy of … G Kassiotis, G Kollias The Journal of experimental medicine 193 (4), 427, 2001 | 448 | 2001 |