| Broad neutralization of SARS-related viruses by human monoclonal antibodies AZ Wec, D Wrapp, AS Herbert, DP Maurer, D Haslwanter, M Sakharkar, ... Science 369 (6504), 731-736, 2020 | 554 | 2020 |
| A role for Fc function in therapeutic monoclonal antibody-mediated protection against Ebola virus BM Gunn, WH Yu, MM Karim, JM Brannan, AS Herbert, AZ Wec, ... Cell host & microbe 24 (2), 221-233. e5, 2018 | 230 | 2018 |
| Systematic analysis of monoclonal antibodies against Ebola virus GP defines features that contribute to protection EO Saphire, SL Schendel, ML Fusco, K Gangavarapu, BM Gunn, AZ Wec, ... Cell 174 (4), 938-952. e13, 2018 | 195 | 2018 |
| Prolonged evolution of the human B cell response to SARS-CoV-2 infection M Sakharkar, CG Rappazzo, WF Wieland-Alter, CL Hsieh, D Wrapp, ... Science immunology 6 (56), eabg6916, 2021 | 183 | 2021 |
| Antibodies from a human survivor define sites of vulnerability for broad protection against ebolaviruses AZ Wec, AS Herbert, CD Murin, EK Nyakatura, DM Abelson, JM Fels, ... Cell 169 (5), 878-890. e15, 2017 | 160 | 2017 |
| A “Trojan horse” bispecific-antibody strategy for broad protection against ebolaviruses AZ Wec, EK Nyakatura, AS Herbert, KA Howell, FW Holtsberg, RR Bakken, ... Science 354 (6310), 350-354, 2016 | 130 | 2016 |
| Protocadherin-1 is essential for cell entry by New World hantaviruses RK Jangra, AS Herbert, R Li, LT Jae, LM Kleinfelter, MM Slough, ... Nature 563 (7732), 559-563, 2018 | 114 | 2018 |
| Immunization-elicited broadly protective antibody reveals ebolavirus fusion loop as a site of vulnerability X Zhao, KA Howell, S He, JM Brannan, AZ Wec, E Davidson, HL Turner, ... Cell 169 (5), 891-904. e15, 2017 | 113 | 2017 |
| Development of a human antibody cocktail that deploys multiple functions to confer pan-ebolavirus protection AZ Wec, ZA Bornholdt, S He, AS Herbert, E Goodwin, AS Wirchnianski, ... Cell host & microbe 25 (1), 39-48. e5, 2019 | 104 | 2019 |
| A two-antibody pan-ebolavirus cocktail confers broad therapeutic protection in ferrets and nonhuman primates ZA Bornholdt, AS Herbert, CE Mire, S He, RW Cross, AZ Wec, ... Cell host & microbe 25 (1), 49-58. e5, 2019 | 97 | 2019 |
| Longitudinal dynamics of the human B cell response to the yellow fever 17D vaccine AZ Wec, D Haslwanter, YN Abdiche, L Shehata, N Pedreño-Lopez, ... Proceedings of the National Academy of Sciences 117 (12), 6675-6685, 2020 | 90 | 2020 |
| Antibody treatment of Ebola and Sudan virus infection via a uniquely exposed epitope within the glycoprotein receptor-binding site KA Howell, X Qiu, JM Brannan, C Bryan, E Davidson, FW Holtsberg, ... Cell reports 15 (7), 1514-1526, 2016 | 90 | 2016 |
| Affinity maturation enhances antibody specificity but compromises conformational stability L Shehata, DP Maurer, AZ Wec, A Lilov, E Champney, T Sun, ... Cell reports 28 (13), 3300-3308. e4, 2019 | 81 | 2019 |
| A combination of receptor-binding domain and N-terminal domain neutralizing antibodies limits the generation of SARS-CoV-2 spike neutralization-escape mutants D Haslwanter, ME Dieterle, AZ Wec, CM O’brien, M Sakharkar, C Florez, ... Mbio 12 (5), 10.1128/mbio. 02473-21, 2021 | 43 | 2021 |
| Structural basis of broad ebolavirus neutralization by a human survivor antibody BR West, AZ Wec, CL Moyer, ML Fusco, PA Ilinykh, K Huang, ... Nature structural & molecular biology 26 (3), 204-212, 2019 | 38 | 2019 |
| Generation and characterization of protective antibodies to Marburg virus JW Froude, T Pelat, S Miethe, SE Zak, AZ Wec, K Chandran, JM Brannan, ... MAbs 9 (4), 696-703, 2017 | 28 | 2017 |
| Broad sarbecovirus neutralizing antibodies define a key site of vulnerability on the SARS-CoV-2 spike protein AZ Wec, D Wrapp, AS Herbert, D Maurer, D Haslwanter, M Sakharkar, ... BioRxiv, 2020 | 26 | 2020 |
| Development of an antibody cocktail for treatment of Sudan virus infection AS Herbert, JW Froude, RA Ortiz, AI Kuehne, DE Dorosky, RR Bakken, ... Proceedings of the National Academy of Sciences 117 (7), 3768-3778, 2020 | 23 | 2020 |
| Human antibody recognizing a quaternary epitope in the Puumala virus glycoprotein provides broad protection against orthohantaviruses E Mittler, AZ Wec, J Tynell, P Guardado-Calvo, J Wigren-Byström, ... Science translational medicine 14 (636), eabl5399, 2022 | 22 | 2022 |
| Viral Hemorrhagic Fever Immunotherapeutic Consortium Systematic analysis of monoclonal antibodies against Ebola virus GP defines features that contribute to protection EO Saphire, SL Schendel, ML Fusco, K Gangavarapu, BM Gunn, AZ Wec, ... Cell 174 (4), 938-952, 2018 | 19 | 2018 |
Kartik ChandranAlbert Einstein College of MedicineVerified email at einsteinmed.edu