Senescence is a developmental mechanism that contributes to embryonic growth and patterning M Storer, A Mas, A Robert-Moreno, M Pecoraro, MC Ortells, V Di Giacomo, ... Cell 155 (5), 1119-1130, 2013 | 1196 | 2013 |
The senescence-associated secretory phenotype induces cellular plasticity and tissue regeneration B Ritschka, M Storer, A Mas, F Heinzmann, MC Ortells, JP Morton, ... Genes & development 31 (2), 172-183, 2017 | 617 | 2017 |
p63 deficiency activates a program of cellular senescence and leads to accelerated aging WM Keyes, Y Wu, H Vogel, X Guo, SW Lowe, AA Mills Genes & development 19 (17), 1986-1999, 2005 | 383 | 2005 |
TAp63 induces senescence and suppresses tumorigenesis in vivo X Guo, WM Keyes, C Papazoglu, J Zuber, W Li, SW Lowe, H Vogel, ... Nature cell biology 11 (12), 1451-1457, 2009 | 303 | 2009 |
Cellular senescence in development, regeneration and disease M Rhinn, B Ritschka, WM Keyes Development 146 (20), dev151837, 2019 | 249 | 2019 |
ΔNp63α is an oncogene that targets chromatin remodeler Lsh to drive skin stem cell proliferation and tumorigenesis WM Keyes, M Pecoraro, V Aranda, E Vernersson-Lindahl, W Li, H Vogel, ... Cell stem cell 8 (2), 164-176, 2011 | 221 | 2011 |
Age-associated inflammation inhibits epidermal stem cell function J Doles, M Storer, L Cozzuto, G Roma, WM Keyes Genes & development 26 (19), 2144-2153, 2012 | 189 | 2012 |
p63 is an essential proapoptotic protein during neural development WB Jacobs, G Govoni, D Ho, JK Atwal, F Barnabe-Heider, WM Keyes, ... Neuron 48 (5), 743-756, 2005 | 154 | 2005 |
p63 heterozygous mutant mice are not prone to spontaneous or chemically induced tumors WM Keyes, H Vogel, MI Koster, X Guo, Y Qi, KM Petherbridge, DR Roop, ... Proceedings of the National Academy of Sciences 103 (22), 8435-8440, 2006 | 120 | 2006 |
Neural potential of a stem cell population in the hair follicle JL Mignone, JL Roig-Lopez, N Fedtsova, DE Schones, LN Manganas, ... Cell cycle 6 (17), 2161-2170, 2007 | 100 | 2007 |
The senotherapeutic drug ABT-737 disrupts aberrant p21 expression to restore liver regeneration in adult mice B Ritschka, T Knauer-Meyer, DS Gonçalves, A Mas, JL Plassat, M Durik, ... Genes & development 34 (7-8), 489-494, 2020 | 81 | 2020 |
Chromatin-bound IκBα regulates a subset of polycomb target genes in differentiation and cancer MC Mulero, D Ferres-Marco, A Islam, P Margalef, M Pecoraro, A Toll, ... Cancer cell 24 (2), 151-166, 2013 | 64 | 2013 |
p63: a new link between senescence and aging WM Keyes, AA Mills Cell Cycle 5 (3), 260-265, 2006 | 53 | 2006 |
Cell cycle gene regulation dynamics revealed by RNA velocity and deep-learning A Riba, A Oravecz, M Durik, S Jiménez, V Alunni, M Cerciat, M Jung, ... Nature communications 13 (1), 2865, 2022 | 45 | 2022 |
ZRF1 controls oncogene-induced senescence through the INK4-ARF locus JD Ribeiro, L Morey, A Mas, A Gutierrez, NM Luis, S Mejetta, H Richly, ... Oncogene 32 (17), 2161-2168, 2013 | 38 | 2013 |
Regulation of apoptosis in the endocardial cushions of the developing chick heart WM Keyes, EJ Sanders American Journal of Physiology-Cell Physiology 282 (6), C1348-C1360, 2002 | 36 | 2002 |
DPY30 regulates pathways in cellular senescence through ID protein expression E Simboeck, A Gutierrez, L Cozzuto, M Beringer, L Caizzi, W M Keyes, ... The EMBO journal 32 (16), 2217-2230, 2013 | 35 | 2013 |
Expression and function of bone morphogenetic proteins in the development of the embryonic endocardial cushions WM Keyes, C Logan, E Parker, EJ Sanders Anatomy and embryology 207, 135-147, 2003 | 35 | 2003 |
ΔNp63α promotes adhesion of metastatic prostate cancer cells to the bone through regulation of CD82 V Di Giacomo, TV Tian, A Mas, M Pecoraro, L Batlle-Morera, L Noya, ... Oncogene 36 (31), 4381-4392, 2017 | 21 | 2017 |
Inducible systems see the light WM Keyes, AA Mills Trends in biotechnology 21 (2), 53-55, 2003 | 17 | 2003 |