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Alpesh Thakker
Alpesh Thakker
Research Fellow in Cancer Metabolism, university of Birmingham
Verified email at bham.ac.uk
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Cited by
Year
Analysis of SMALP co-extracted phospholipids shows distinct membrane environments for three classes of bacterial membrane protein
ACK Teo, SC Lee, NL Pollock, Z Stroud, S Hall, A Thakker, AR Pitt, ...
Scientific Reports 9 (1), 1813, 2019
912019
Oncogenic IDH1 mutations promote enhanced proline synthesis through PYCR1 to support the maintenance of mitochondrial redox homeostasis
KER Hollinshead, H Munford, KL Eales, C Bardella, C Li, ...
Cell reports 22 (12), 3107-3114, 2018
862018
The effects of oxygenation on ex vivo kidneys undergoing hypothermic machine perfusion
K Patel, TB Smith, DAH Neil, A Thakker, Y Tsuchiya, EB Higgs, ...
Transplantation 103 (2), 314-322, 2019
662019
Intracellular sodium elevation reprograms cardiac metabolism
D Aksentijević, A Karlstaedt, MV Basalay, BA O’Brien, D Sanchez-Tatay, ...
Nature communications 11 (1), 4337, 2020
542020
Anti-myeloperoxidase antibodies attenuate the monocyte response to LPS and shape macrophage development
RJ Popat, S Hakki, A Thakker, AM Coughlan, J Watson, MA Little, ...
JCI insight 2 (2), 2017
372017
Ligand-induced conformational changes in a SMALP-encapsulated GPCR.
SJ Routledge, M Jamshad, HA Little, YP Lin, J Simms, A Thakker, ...
Biochimica et Biophysica Acta (BBA)-Biomembranes 1862 (6), 183235, 2020
342020
Loss of SDHB promotes dysregulated iron homeostasis, oxidative stress, and sensitivity to ascorbate
J Goncalves, S Moog, A Morin, G Gentric, S Müller, AP Morrell, ...
Cancer Research 81 (13), 3480-3494, 2021
332021
Metabolic tracing reveals novel adaptations to skeletal muscle cell energy production pathways in response to NAD+ depletion
LA Oakey, RS Fletcher, YS Elhassan, DM Cartwright, CL Doig, A Garten, ...
Wellcome open research 3, 2018
262018
Succinate dehydrogenase deficiency in a chromaffin cell model retains metabolic fitness through the maintenance of mitochondrial NADH oxidoreductase function
K Kľučková, A Thakker, L Vettore, C Escribano-Gonzalez, RL Hindshaw, ...
The FASEB Journal 34 (1), 303-315, 2020
232020
A human pluripotent stem cell model for the analysis of metabolic dysfunction in hepatic steatosis
MC Sinton, J Meseguer-Ripolles, B Lucendo-Villarin, S Wernig-Zorc, ...
Iscience 24 (1), 2021
212021
HOCl-modified phosphatidylcholines induce apoptosis and redox imbalance in HUVEC-ST cells
A Robaszkiewicz, G Bartosz, AR Pitt, A Thakker, RA Armstrong, ...
Archives of biochemistry and biophysics 548, 1-10, 2014
172014
Tolerogenic effects of 1, 25-dihydroxyvitamin D on dendritic cells involve induction of fatty acid synthesis
AM Garcia, EL Bishop, D Li, LE Jeffery, A Garten, A Thakker, M Certo, ...
The Journal of Steroid Biochemistry and Molecular Biology 211, 105891, 2021
132021
Prolyl-4-hydroxylase 3 maintains β cell glucose metabolism during fatty acid excess in mice
D Nasteska, F Cuozzo, K Viloria, EM Johnson, A Thakker, RB Bakar, ...
JCI insight 6 (16), 2021
72021
Dafforn. T. R, Spickett. CM, Roper, DI (2019). Analysis of SMALP co-extracted phospholipids shows distinct membrane environments for three classes of bacterial membrane protein
ACK Teo, SC Lee, NL Pollock, Z Stroud, S Hall, A Thakker, AR Pitt
Scientific Reports 9 (1), 1-10, 0
6
Oncogenic IDH1 mutations promote enhanced proline synthesis through PYCR1 to support the maintenance of mitochondrial redox homeostasis. Cell Rep 22 (12): 3107–3114
KER Hollinshead, H Munford, KL Eales, C Bardella, C Li, ...
pubmed. ncbi. nlm. nih. gov/29562167, 2018
52018
A Targeted Mass Spectrometry Approach to detect and quantify Oxidised Phospholipids in plasma samples of Diabetic patients
A Thakker, CM Spickett, A Pitt
BioRxiv, 741132, 2019
22019
VHL-deficiency leads to reductive stress in renal cells
H Vellama, KL Eskla, H Eichelmann, A Hüva, DA Tennant, A Thakker, ...
Free Radical Biology and Medicine 208, 1-12, 2023
12023
Macrovesicular steatosis in nonalcoholic fatty liver disease is a consequence of purine nucleotide cycle driven fumarate accumulation
MC Sinton, B Lucendo Villarin, J Meseguer Ripolles, S Wernig-Zorc, ...
bioRxiv, 2020.06. 23.166728, 2020
12020
The prolyl hydroxylase PHD3 maintains β-cell glucose metabolism during fatty acid excess
D Nasteska, F Cuozzo, A Thakker, RB Bakar, R Westbrook, I Akerman, ...
bioRxiv, 2020.04. 30.068106, 2020
12020
Prolyl-hydroxylase 3 maintains [beta]-cell glucose-sensing under metabolic stress
F Cuozzo, D Nasteska, A Thakker, R Westbrook, RB Bakar, J Cantley, ...
Endocrine Abstracts 65, 2019
12019
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