Human monocytes engage an alternative inflammasome pathway MM Gaidt, TS Ebert, D Chauhan, T Schmidt, JL Schmid-Burgk, F Rapino, ... Immunity 44 (4), 833-846, 2016 | 787 | 2016 |
Cell intrinsic immunity spreads to bystander cells via the intercellular transfer of cGAMP A Ablasser, JL Schmid-Burgk, I Hemmerling, GL Horvath, T Schmidt, ... Nature 503 (7477), 530-534, 2013 | 649 | 2013 |
RNA-guided DNA insertion with CRISPR-associated transposases J Strecker, A Ladha, Z Gardner, JL Schmid-Burgk, KS Makarova, ... Science 365 (6448), 48-53, 2019 | 587 | 2019 |
The DNA inflammasome in human myeloid cells is initiated by a STING-cell death program upstream of NLRP3 MM Gaidt, TS Ebert, D Chauhan, K Ramshorn, F Pinci, S Zuber, F O’Duill, ... Cell 171 (5), 1110-1124. e18, 2017 | 518 | 2017 |
NLRP3 inflammasome activity is negatively controlled by miR-223 F Bauernfeind, A Rieger, FA Schildberg, PA Knolle, JL Schmid-Burgk, ... The Journal of Immunology 189 (8), 4175-4181, 2012 | 497 | 2012 |
Inflammasomes: current understanding and open questions F Bauernfeind, A Ablasser, E Bartok, S Kim, J Schmid-Burgk, T Cavlar, ... Cellular and Molecular Life Sciences 68, 765-783, 2011 | 481 | 2011 |
A genome-wide CRISPR (clustered regularly interspaced short palindromic repeats) screen identifies NEK7 as an essential component of NLRP3 inflammasome activation JL Schmid-Burgk, D Chauhan, T Schmidt, TS Ebert, J Reinhardt, E Endl, ... Journal of Biological Chemistry 291 (1), 103-109, 2016 | 438 | 2016 |
Mycobacterium tuberculosis differentially activates cGAS-and inflammasome-dependent intracellular immune responses through ESX-1 R Wassermann, MF Gulen, C Sala, SG Perin, Y Lou, J Rybniker, ... Cell host & microbe 17 (6), 799-810, 2015 | 398 | 2015 |
Engineering of CRISPR-Cas12b for human genome editing J Strecker, S Jones, B Koopal, J Schmid-Burgk, B Zetsche, L Gao, ... Nature communications 10 (1), 212, 2019 | 358 | 2019 |
Diverse enzymatic activities mediate antiviral immunity in prokaryotes L Gao, H Altae-Tran, F Böhning, KS Makarova, M Segel, JL Schmid-Burgk, ... Science 369 (6507), 1077-1084, 2020 | 353 | 2020 |
Structure-guided multivalent nanobodies block SARS-CoV-2 infection and suppress mutational escape PA Koenig, H Das, H Liu, BM Kümmerer, FN Gohr, LM Jenster, ... Science 371 (6530), eabe6230, 2021 | 347 | 2021 |
A ligation-independent cloning technique for high-throughput assembly of transcription activator–like effector genes JL Schmid-Burgk, T Schmidt, V Kaiser, K Höning, V Hornung Nature biotechnology 31 (1), 76-81, 2013 | 339 | 2013 |
Caspase‐4 mediates non‐canonical activation of the NLRP3 inflammasome in human myeloid cells JL Schmid‐Burgk, MM Gaidt, T Schmidt, TS Ebert, E Bartok, V Hornung European journal of immunology 45 (10), 2911-2917, 2015 | 331 | 2015 |
A conserved histidine in the RNA sensor RIG-I controls immune tolerance to N1-2′ O-methylated self RNA C Schuberth-Wagner, J Ludwig, AK Bruder, AM Herzner, T Zillinger, ... Immunity 43 (1), 41-51, 2015 | 294 | 2015 |
Antiviral activity of human OASL protein is mediated by enhancing signaling of the RIG-I RNA sensor J Zhu, Y Zhang, A Ghosh, RA Cuevas, A Forero, J Dhar, MS Ibsen, ... Immunity 40 (6), 936-948, 2014 | 251 | 2014 |
TREX1 deficiency triggers cell-autonomous immunity in a cGAS-dependent manner A Ablasser, I Hemmerling, JL Schmid-Burgk, R Behrendt, A Roers, ... The Journal of Immunology 192 (12), 5993-5997, 2014 | 249 | 2014 |
Optical pooled screens in human cells D Feldman, A Singh, JL Schmid-Burgk, RJ Carlson, A Mezger, AJ Garrity, ... Cell 179 (3), 787-799. e17, 2019 | 229 | 2019 |
Early IFN-α signatures and persistent dysfunction are distinguishing features of NK cells in severe COVID-19 B Krämer, R Knoll, L Bonaguro, M ToVinh, J Raabe, ... Immunity 54 (11), 2650-2669. e14, 2021 | 187 | 2021 |
Influenza virus adaptation PB2-627K modulates nucleocapsid inhibition by the pathogen sensor RIG-I M Weber, H Sediri, U Felgenhauer, I Binzen, S Bänfer, R Jacob, ... Cell host & microbe 17 (3), 309-319, 2015 | 171 | 2015 |
CRISPaint allows modular base-specific gene tagging using a ligase-4-dependent mechanism JL Schmid-Burgk, K Höning, TS Ebert, V Hornung Nature communications 7 (1), 12338, 2016 | 170 | 2016 |