Kinase-inactivated ULK proteins inhibit autophagy via their conserved C-terminal domains using an Atg13-independent mechanism EYW Chan, A Longatti, NC McKnight, SA Tooze Molecular and cellular biology 29 (1), 157-171, 2009 | 536 | 2009 |
SOX9 is expressed in normal prostate basal cells and regulates androgen receptor expression in prostate cancer cells H Wang, NC McKnight, T Zhang, ML Lu, SP Balk, X Yuan Cancer research 67 (2), 528-536, 2007 | 172 | 2007 |
Beclin 1, an essential component and master regulator of PI3K-III in health and disease NC McKnight, Z Yue Current pathobiology reports 1, 231-238, 2013 | 161 | 2013 |
Beclin 1 is required for neuron viability and regulates endosome pathways via the UVRAG-VPS34 complex NC McKnight, Y Zhong, MS Wold, S Gong, GR Phillips, Z Dou, Y Zhao, ... PLoS genetics 10 (10), e1004626, 2014 | 144 | 2014 |
Genome‐wide siRNA screen reveals amino acid starvation‐induced autophagy requires SCOC and WAC NC McKnight, HBJ Jefferies, EA Alemu, RE Saunders, M Howell, ... The EMBO journal 31 (8), 1931-1946, 2012 | 130 | 2012 |
A direct β-catenin-independent interaction between androgen receptor and T cell factor 4 AL Amir, M Barua, NC McKnight, S Cheng, X Yuan, SP Balk Journal of Biological Chemistry 278 (33), 30828-30834, 2003 | 105 | 2003 |
CERT depletion predicts chemotherapy benefit and mediates cytotoxic and polyploid‐specific cancer cell death through autophagy induction AJX Lee, R Roylance, J Sander, P Gorman, D Endesfelder, M Kschischo, ... The Journal of pathology 226 (3), 482-494, 2012 | 59 | 2012 |
Trafficking and signaling in mammalian autophagy SA Tooze, HBJ Jefferies, E Kalie, A Longatti, FE Mcalpine, NC Mcknight, ... IUBMB life 62 (7), 503-508, 2010 | 51 | 2010 |
Activation of nonreceptor tyrosine kinase Bmx/Etk mediated by phosphoinositide 3-kinase, epidermal growth factor receptor, and ErbB3 in prostate cancer cells X Jiang, RA Borgesi, NC McKnight, R Kaur, CL Carpenter, SP Balk Journal of Biological Chemistry 282 (45), 32689-32698, 2007 | 46 | 2007 |
Combining an mTOR antagonist and receptor tyrosine kinase inhibitors for the treatment of prostate cancer D Masiello, MG Mohi, NC McKnight, B Smith, BG Neel, SP Balk, ... Cancer Biology & Therapy 6 (2), 195-201, 2007 | 30 | 2007 |
High-throughput screening approaches to identify regulators of mammalian autophagy J Joachim, M Jiang, NC McKnight, M Howell, SA Tooze Methods 75, 96-104, 2015 | 20 | 2015 |
Coiling up with SCOC and WAC: two new regulators of starvation-induced autophagy J Joachim, M Wirth, NC McKnight, SA Tooze Autophagy 8 (9), 1397-1400, 2012 | 18 | 2012 |
The cellular process of autophagy and control of autophagy in neurons NC McKnight, N Mizushima, Z Yue Autophagy of the Nervous System: Cellular Self-Digestion in Neurons and …, 2012 | 4 | 2012 |
The effect of combination growth factor receptor and mTOR inhibitors in androgen-independent prostate cancer cell tines. GJ Bubley, D Masiello, N McKnight, B Smith, G Mohi, B Neel, S Balk CLINICAL CANCER RESEARCH 9 (16), 6179S-6180S, 2003 | 2 | 2003 |
WAC is a positive regulator of autophagy that interacts with GM130 on the cis Golgi J Joachim, N McKnight, H Jefferies, S Tooze FEBS JOURNAL 281, 703-704, 2014 | | 2014 |
AUTOPHAGY IN HUNTINGTON’S AND PARKINSON’S DISEASES: PATHOGENIC MECHANISMS AND THERAPEUTIC POTENTIALS J Lim, LG Friedman, NC McKnight, Z Yue Autophagy of the Nervous System: Cellular Self-Digestion in Neurons and …, 2012 | | 2012 |
Molecular insights into autophagy SA Tooze, E Kalie, A Longatti, NC McKnight, A Orsi, HEJ Polson FEBS JOURNAL 278, 21-21, 2011 | | 2011 |
A genome-wide screen for starvation-induced autophagy identifies new modulators of autophagy NC McKnight UCL (University College London), 2011 | | 2011 |
Elucidating the role of WAC in autophagy J Joachim, N McKnight, H Jefferies, S Tooze | | |