A cancer cell program promotes T cell exclusion and resistance to checkpoint blockade L Jerby-Arnon, P Shah, MS Cuoco, C Rodman, MJ Su, JC Melms, ... Cell 175 (4), 984-997. e24, 2018 | 1086 | 2018 |
The neuropeptide NMU amplifies ILC2-driven allergic lung inflammation A Wallrapp, SJ Riesenfeld, PR Burkett, REE Abdulnour, J Nyman, ... Nature 549 (7672), 351-356, 2017 | 555 | 2017 |
The human and mouse enteric nervous system at single-cell resolution E Drokhlyansky, CS Smillie, N Van Wittenberghe, M Ericsson, GK Griffin, ... Cell 182 (6), 1606-1622. e23, 2020 | 381 | 2020 |
Spatially organized multicellular immune hubs in human colorectal cancer K Pelka, M Hofree, JH Chen, S Sarkizova, JD Pirl, V Jorgji, A Bejnood, ... Cell 184 (18), 4734-4752. e20, 2021 | 372 | 2021 |
Tumor and immune reprogramming during immunotherapy in advanced renal cell carcinoma K Bi, MX He, Z Bakouny, A Kanodia, S Napolitano, J Wu, G Grimaldi, ... Cancer cell 39 (5), 649-661. e5, 2021 | 359 | 2021 |
A single-cell landscape of high-grade serous ovarian cancer B Izar, I Tirosh, EH Stover, I Wakiro, MS Cuoco, I Alter, C Rodman, ... Nature medicine 26 (8), 1271-1279, 2020 | 349 | 2020 |
Single-cell meta-analysis of SARS-CoV-2 entry genes across tissues and demographics C Muus, MD Luecken, G Eraslan, L Sikkema, A Waghray, G Heimberg, ... Nature medicine 27 (3), 546-559, 2021 | 315 | 2021 |
Cycling cancer persister cells arise from lineages with distinct programs Y Oren, M Tsabar, MS Cuoco, L Amir-Zilberstein, HF Cabanos, JC Hütter, ... Nature 596 (7873), 576-582, 2021 | 300 | 2021 |
Pan-cancer single-cell RNA-seq identifies recurring programs of cellular heterogeneity GS Kinker, AC Greenwald, R Tal, Z Orlova, MS Cuoco, JM McFarland, ... Nature genetics 52 (11), 1208-1218, 2020 | 287 | 2020 |
Integrated analyses of single-cell atlases reveal age, gender, and smoking status associations with cell type-specific expression of mediators of SARS-CoV-2 viral entry and … C Muus, MD Luecken, G Eraslan, A Waghray, G Heimberg, L Sikkema, ... BioRxiv, 2020.04. 19.049254, 2020 | 259 | 2020 |
Single-nucleus cross-tissue molecular reference maps toward understanding disease gene function G Eraslan, E Drokhlyansky, S Anand, E Fiskin, A Subramanian, M Slyper, ... Science 376 (6594), eabl4290, 2022 | 249 | 2022 |
Acquired HER2 mutations in ER+ metastatic breast cancer confer resistance to estrogen receptor–directed therapies U Nayar, O Cohen, C Kapstad, MS Cuoco, AG Waks, SA Wander, ... Nature genetics 51 (2), 207-216, 2019 | 229 | 2019 |
Single-nucleus and spatial transcriptome profiling of pancreatic cancer identifies multicellular dynamics associated with neoadjuvant treatment WL Hwang, KA Jagadeesh, JA Guo, HI Hoffman, P Yadollahpour, ... Nature genetics 54 (8), 1178-1191, 2022 | 174 | 2022 |
Conventional type I dendritic cells maintain a reservoir of proliferative tumor-antigen specific TCF-1+ CD8+ T cells in tumor-draining lymph nodes JM Schenkel, RH Herbst, D Canner, A Li, M Hillman, SL Shanahan, ... Immunity 54 (10), 2338-2353. e6, 2021 | 169 | 2021 |
Multimodal pooled Perturb-CITE-seq screens in patient models define mechanisms of cancer immune evasion CJ Frangieh, JC Melms, PI Thakore, KR Geiger-Schuller, P Ho, ... Nature genetics 53 (3), 332-341, 2021 | 163 | 2021 |
Transcriptional mediators of treatment resistance in lethal prostate cancer MX He, MS Cuoco, J Crowdis, A Bosma-Moody, Z Zhang, K Bi, A Kanodia, ... Nature medicine 27 (3), 426-433, 2021 | 118 | 2021 |
Acquired FGFR and FGF Alterations Confer Resistance to Estrogen Receptor (ER) Targeted Therapy in ER+ Metastatic Breast Cancer P Mao, O Cohen, KJ Kowalski, JG Kusiel, JE Buendia-Buendia, ... Clinical Cancer Research 26 (22), 5974-5989, 2020 | 118 | 2020 |
Opposing immune and genetic mechanisms shape oncogenic programs in synovial sarcoma L Jerby-Arnon, C Neftel, ME Shore, HR Weisman, ND Mathewson, ... Nature medicine 27 (2), 289-300, 2021 | 87 | 2021 |
IL-33 signaling alters regulatory T cell diversity in support of tumor development A Li, RH Herbst, D Canner, JM Schenkel, OC Smith, JY Kim, M Hillman, ... Cell reports 29 (10), 2998-3008. e8, 2019 | 72 | 2019 |
Single-nucleus and spatial transcriptomics of archival pancreatic cancer reveals multi-compartment reprogramming after neoadjuvant treatment WL Hwang, KA Jagadeesh, JA Guo, HI Hoffman, P Yadollahpour, ... BioRxiv, 2020.08. 25.267336, 2020 | 37 | 2020 |