Advantages of Single-Nucleus over Single-Cell RNA Sequencing of Adult Kidney: Rare Cell Types and Novel Cell States Revealed in Fibrosis H Wu, Y Kirita, EL Donnelly, BD Humphreys Journal of the American Society of Nephrology 30 (1), 23-32, 2019 | 605 | 2019 |
Comparative Analysis and Refinement of Human PSC-Derived Kidney Organoid Differentiation with Single-Cell Transcriptomics H Wu, K Uchimura, EL Donnelly, Y Kirita, SA Morris, BD Humphreys Cell Stem Cell 23 (6), 869-881, 2018 | 520 | 2018 |
Toll-like receptor 4 promotes tubular inflammation in diabetic nephropathy M Lin, WH Yiu, H Wu, LYY Chan, JCK Leung, WS Au, KW Chan, KN Lai, ... Journal of the American Society of Nephrology 23 (1), 86-102, 2012 | 437 | 2012 |
The single-cell transcriptomic landscape of early human diabetic nephropathy PC Wilson, H Wu, Y Kirita, K Uchimura, N Ledru, HG Rennke, PA Welling, ... Proceedings of the National Academy of Sciences 116 (39), 19619-19625, 2019 | 402 | 2019 |
Cell profiling of mouse acute kidney injury reveals conserved cellular responses to injury Y Kirita, H Wu, K Uchimura, PC Wilson, BD Humphreys Proceedings of the National Academy of Sciences, 2020 | 390 | 2020 |
Single-Cell Transcriptomics of a Human Kidney Allograft Biopsy Specimen Defines a Diverse Inflammatory Response H Wu, AF Malone, EL Donnelly, Y Kirita, K Uchimura, SM Ramakrishnan, ... Journal of the American Society of Nephrology 29 (8), 2069-2080, 2018 | 330 | 2018 |
Single cell transcriptional and chromatin accessibility profiling redefine cellular heterogeneity in the adult human kidney Y Muto, PC Wilson, N Ledru, H Wu, H Dimke, W Sushrut S., ... Nature Communications 12, 2190 (2021), 2021 | 282 | 2021 |
Trans-ethnic kidney function association study reveals putative causal genes and effects on kidney-specific disease aetiologies AP Morris, TH Le, H Wu, A Akbarov, PPJ Most, A Mahajan, G Hemani, ... Nature Communications 10 (1), 29, 2019 | 143 | 2019 |
The TLR4 antagonist CRX-526 protects against advanced diabetic nephropathy M Lin, WH Yiu, RX Li, H Wu, DWL Wong, LYY Chan, JCK Leung, KN Lai, ... Kidney international 83 (5), 887-900, 2013 | 136 | 2013 |
FOXM1 drives proximal tubule proliferation during repair from acute ischemic kidney injury M Chang-Panesso, FF Kadyrov, M Lalli, H Wu, S Ikeda, E Kefaloyianni, ... The Journal of Clinical Investigation 129 (12), 5501-5517, 2019 | 132 | 2019 |
Mapping the single-cell transcriptomic response of murine diabetic kidney disease to therapies H Wu, RG Villalobos, X Yao, D Reilly, T Chen, M Rankin, E Myshkin, ... Cell Metabolism, 2022 | 119 | 2022 |
Kallistatin protects against diabetic nephropathy in db/db mice by suppressing AGE-RAGE-induced oxidative stress WH Yiu, DWL Wong, H Wu, RX Li, I Yam, LYY Chan, JCK Leung, HY Lan, ... Kidney international 89 (2), 386-398, 2016 | 104 | 2016 |
Isolation and culture of primary bovine embryonic stem cell colonies by a novel method S Cao, F Wang, Z Chen, Z Liu, C Mei, H Wu, J Huang, C Li, L Zhou, L Liu Journal of Experimental Zoology Part A: Ecological Genetics and Physiology …, 2009 | 96 | 2009 |
Human Pluripotent Stem Cell-Derived Kidney Organoids with Improved Collecting Duct Maturation and Injury Modeling K Uchimura, H Wu, Y Yoshimura, BD Humphreys Cell Reports 33 (11), 108514, 2020 | 93 | 2020 |
Comprehensive single-cell transcriptional profiling defines shared and unique epithelial injury responses during kidney fibrosis H Li, EE Dixon, H Wu, BD Humphreys Cell metabolism 34 (12), 1977-1998. e9, 2022 | 92 | 2022 |
Spatially Resolved Transcriptomic Analysis of Acute Kidney Injury in a Female Murine Model EE Dixon, H Wu, Y Muto, PC Wilson, BD Humphreys Journal of the American Society of Nephrology 33 (2), 279-289, 2022 | 92 | 2022 |
Parabiosis and single-cell RNA sequencing reveal a limited contribution of monocytes to myofibroblasts in kidney fibrosis R Kramann, F Machado, H Wu, T Kusaba, K Hoeft, RK Schneider, ... JCI Insight 3 (9), 2018 | 90 | 2018 |
Mesenchymal stem cells modulate albumin-induced renal tubular inflammation and fibrosis H Wu, WH Yiu, RX Li, DWL Wong, JCK Leung, LYY Chan, Y Zhang, ... PLoS One 9 (3), e90883, 2014 | 90 | 2014 |
The promise of single-cell RNA sequencing for kidney disease investigation H Wu, BD Humphreys Kidney international 92 (6), 1334-1342, 2017 | 87 | 2017 |
Complement C5a inhibition moderates lipid metabolism and reduces tubulointerstitial fibrosis in diabetic nephropathy WH Yiu, RX Li, DWL Wong, H Wu, KW Chan, LYY Chan, JCK Leung, ... Nephrology Dialysis Transplantation 33 (8), 1323-1332, 2017 | 85 | 2017 |