Biochemical engineering of the N-acyl side chain of sialic acid: biological implications OT Keppler, R Horstkorte, M Pawlita, C Schmidt, W Reutter Glycobiology 11 (2), 11R-18R, 2001 | 577 | 2001 |
Sialylation is essential for early development in mice M Schwarzkopf, KP Knobeloch, E Rohde, S Hinderlich, N Wiechens, ... Proceedings of the National Academy of Sciences 99 (8), 5267-5270, 2002 | 430 | 2002 |
Increasing the sialylation of therapeutic glycoproteins: the potential of the sialic acid biosynthetic pathway K Bork, R Horstkorte, W Weidemann Journal of pharmaceutical sciences 98 (10), 3499-3508, 2009 | 209 | 2009 |
Metabolic Glycoengineering with N‐Acyl Side Chain Modified Mannosamines PR Wratil, R Horstkorte, W Reutter Angewandte Chemie International Edition 55 (33), 9482-9512, 2016 | 119 | 2016 |
UDP-GlcNAc 2-epimerase/ManNAc kinase (GNE): a master regulator of sialic acid synthesis R Gerardy-Schahn, P Delannoy, M von Itzstein, S Hinderlich, ... SialoGlyco Chemistry and Biology I: Biosynthesis, structural diversity and …, 2015 | 112 | 2015 |
Recombinant glycoproteins, method for the production thereof, medicaments containing said glycoproteins and use thereof W Reutter, R Tauber, R Horstkorte, S Nöhring, M Gohlke, R Nuck, ... US Patent 6,692,931, 2004 | 109 | 2004 |
Biochemical Engineering of Neural Cell Surfaces by the SyntheticN-Propanoyl-substituted Neuraminic Acid Precursor C Schmidt, P Stehling, J Schnitzer, W Reutter, R Horstkorte Journal of Biological Chemistry 273 (30), 19146-19152, 1998 | 103 | 1998 |
The intracellular concentration of sialic acid regulates the polysialylation of the neural cell adhesion molecule K Bork, W Reutter, R Gerardy-Schahn, R Horstkorte FEBS letters 579 (22), 5079-5083, 2005 | 102 | 2005 |
The homozygous M712T mutation of UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase results in reduced enzyme activities but not in altered overall cellular … S Hinderlich, I Salama, I Eisenberg, T Potikha, LR Mantey, KJ Yarema, ... FEBS letters 566 (1-3), 105-109, 2004 | 94 | 2004 |
Localization of UDP-GlcNAc 2-epimerase/ManAc kinase (GNE) in the Golgi complex and the nucleus of mammalian cells S Krause, S Hinderlich, S Amsili, R Horstkorte, H Wiendl, Z Argov, ... Experimental cell research 304 (2), 365-379, 2005 | 91 | 2005 |
The neural cell adhesion molecule is associated with major components of the cytoskeleton B Büttner, C Kannicht, W Reutter, R Horstkorte Biochemical and biophysical research communications 310 (3), 967-971, 2003 | 84 | 2003 |
Enhanced sialylation of EPO by overexpression of UDP-GlcNAc 2-epimerase/ManAc kinase containing a sialuria mutation in CHO cells K Bork, W Reutter, W Weidemann, R Horstkorte FEBS letters 581 (22), 4195-4198, 2007 | 80 | 2007 |
Biochemical engineering of cell surface sialic acids stimulates axonal growth B Büttner, C Kannicht, C Schmidt, K Löster, W Reutter, HY Lee, S Nöhring, ... Journal of Neuroscience 22 (20), 8869-8875, 2002 | 79 | 2002 |
Primary structure and expression analysis of human UDP-N-acetyl-glucosamine-2-epimerase/N-acetylmannosamine kinase, the bifunctional enzyme in neuraminic acid biosynthesis L Lucka, M Krause, K Danker, W Reutter, R Horstkorte FEBS letters 454 (3), 341-344, 1999 | 78 | 1999 |
Evidence for Cis Interaction and Cooperative Signalling by the Heat‐stable Antigen Nectadrin (murine CD24) and the Cell Adhesion Molecule L1 in Neurons G Kadmon, F von Bohlen und Halbach, R Horstkorte, M Eckert, P Altevogt, ... European Journal of Neuroscience 7 (5), 993-1004, 1995 | 74 | 1995 |
Selective inhibition of polysialyltransferase ST8SiaII by unnatural sialic acids R Horstkorte, M Mühlenhoff, W Reutter, S Nöhring, ... Experimental cell research 298 (1), 268-274, 2004 | 65 | 2004 |
Reduced sialylation status in UDP-N-acetylglucosamine-2-epimerase/N-acetylmannosamine kinase (GNE)-deficient mice D Gagiannis, A Orthmann, I Danßmann, M Schwarzkopf, W Weidemann, ... Glycoconjugate journal 24 (2), 125-130, 2007 | 64 | 2007 |
Increasing batch-to-batch reproducibility of CHO-cell cultures using a model predictive control approach M Aehle, K Bork, S Schaepe, A Kuprijanov, R Horstkorte, R Simutis, ... Cytotechnology 64, 623-634, 2012 | 63 | 2012 |
Engineering the sialic acid in organs of mice using N-propanoylmannosamine D Gagiannis, R Gossrau, W Reutter, M Zimmermann-Kordmann, ... Biochimica et Biophysica Acta (BBA)-General Subjects 1770 (2), 297-306, 2007 | 63 | 2007 |
Tissue expression and amino acid sequence of murine UDP‐N‐acetylglucosamine‐2‐epimerase/N‐acetylmannosamine kinase R Horstkorte, S Nöhring, N Wiechens, M Schwarzkopf, K Danker, ... European journal of biochemistry 260 (3), 923-927, 1999 | 60 | 1999 |